Tiina-Kaisa Kukko-Lukjanov
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Tiina-Kaisa Kukko-Lukjanov has a total of 12 co-authors. Here are the top co-authors by number of shared publications:
- Anna Hielm-Björkman
University of Helsinki, Helsinki, Finland
1 shared publication Anne Muhle
Evidensia Espoo Animal Hospital , Espoo
1 shared publication- Johanna Anturaniemi
Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki
1 shared publication - Kristiina A. Vuori
Faculty of Veterinary Medicine, University of Helsinki Department of Equine and Small Animal Medicine Helsinki
1 shared publication - Manal Hemida
Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland
1 shared publication - Robin Moore
Department of Equine and Small Animal Medicine, University of Helsinki, Finland
1 shared publication
Latest Publications
- Open Access
- 10 October 2025
- Published by Elsevier in Neuroscience
- Vol. 588, 160-173
Physiological and kainate-induced network activity of organotypic hippocampal slices depends on culture medium on multielectrode array
- 10 October 2025
- Published by Elsevier in Neuroscience
- Vol. 588, 160-173
Open AccessPhysiological and kainate-induced network activity of organotypic hippocampal slices depends on culture medium on multielectrode array
- Open Access
- 1 May 2023
- Published by Oxford University Press (OUP) in Journal of Veterinary Internal Medicine
- Vol. 37 (3) , 1100-1110
Mineral, trace element, and toxic metal concentration in hair from dogs with idiopathic epilepsy compared to healthy controls
Background: Altered trace element status is associated with epilepsy in humans and dogs with idiopathic epilepsy (IE). Objectives: Compare hair element concentrations in epileptic and healthy dogs. Animals: Sixty-three dogs with IE (53 treated, 10 untreated) and 42 controls. Methods: Case-control study using ICP-MS to determine hair calcium, magnesium, phosphorus, sodium, potassium, iron, copper, manganese, zinc, selenium, chromium, lead, mercury, cadmium, arsenic, aluminum, and nickel concentration. Groups were compared using nonparametric tests. Results were controlled for diet, sex, age, and hair color using generalized linear mixed models. Results: Compared to healthy controls, dogs with IE had lower hair phosphorus (mean ± SD; IE: 286.19 ± 69.62 μg/g, healthy: 324.52 ± 58.69 μg/g; P = .001), higher hair copper (IE: 10.97 ± 3.51 μg/g, healthy: 8.41 ± 1.27 μg/g; P < .001), zinc (IE: 158.25 ± 19.64 μg/g, healthy: 144.76 ± 32.18 μg/g; P < .001), copper/zinc ratio (IE: 0.07 ± 0.02, healthy: 0.06 ± 0.01; P = .003), selenium (IE: 1.65 ± 0.43 μg/g, healthy: 0.94 ± 0.73 μg/g; P < .001), and arsenic (IE: 0.40 ± 0.78 μg/g, healthy: 0.05 ± 0.08 μg/g; P < .001). When comparing treated and untreated epileptic dogs with healthy dogs, the differences in phosphorus and selenium remained significant for both groups, whereas the differences in copper, zinc, and arsenic were significant only for treated dogs. Potassium bromide treatment was strongly associated with high hair arsenic (P = .000). Conclusions and Clinical Importance: Altered trace element status could be involved in the pathophysiology of IE in dogs. Antiseizure drugs might affect trace element and arsenic metabolism.
- 1 May 2023
- Published by Oxford University Press (OUP) in Journal of Veterinary Internal Medicine
- Vol. 37 (3) , 1100-1110
Open AccessMineral, trace element, and toxic metal concentration in hair from dogs with idiopathic epilepsy compared to healthy controls
Background: Altered trace element status is associated with epilepsy in humans and dogs with idiopathic epilepsy (IE). Objectives: Compare hair element concentrations in epileptic and healthy dogs. Animals: Sixty-three dogs with IE (53 treated, 10 untreated) and 42 controls. Methods: Case-control study using ICP-MS to determine hair calcium, magnesium, phosphorus, sodium, potassium, iron, copper, manganese, zinc, selenium, chromium, lead, mercury, cadmium, arsenic, aluminum, and nickel concentration. Groups were compared using nonparametric tests. Results were controlled for diet, sex, age, and hair color using generalized linear mixed models. Results: Compared to healthy controls, dogs with IE had lower hair phosphorus (mean ± SD; IE: 286.19 ± 69.62 μg/g, healthy: 324.52 ± 58.69 μg/g; P = .001), higher hair copper (IE: 10.97 ± 3.51 μg/g, healthy: 8.41 ± 1.27 μg/g; P < .001), zinc (IE: 158.25 ± 19.64 μg/g, healthy: 144.76 ± 32.18 μg/g; P < .001), copper/zinc ratio (IE: 0.07 ± 0.02, healthy: 0.06 ± 0.01; P = .003), selenium (IE: 1.65 ± 0.43 μg/g, healthy: 0.94 ± 0.73 μg/g; P < .001), and arsenic (IE: 0.40 ± 0.78 μg/g, healthy: 0.05 ± 0.08 μg/g; P < .001). When comparing treated and untreated epileptic dogs with healthy dogs, the differences in phosphorus and selenium remained significant for both groups, whereas the differences in copper, zinc, and arsenic were significant only for treated dogs. Potassium bromide treatment was strongly associated with high hair arsenic (P = .000). Conclusions and Clinical Importance: Altered trace element status could be involved in the pathophysiology of IE in dogs. Antiseizure drugs might affect trace element and arsenic metabolism.