Gabriela Fabiana Soares Alegre
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Gabriela Fabiana Soares Alegre has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
Glaucia Maria Pastore
3 shared publications- Augusto César Costa-Santos
Department of Food Science and Nutrition, School of Food, Engineering, University of Campinas, Monteiro Lobato Street, 80, Campinas 13083-862, SP, Brazil
1 shared publication - Cynthia Tereza Corrêa da Silva Miranda
Laboratory of Bioflavours and Bioactive Compounds, Department of Food Science, Faculty of Food Engineering, University of Campinas, Campinas 13083-862, SP, Brazil
1 shared publication Eduardo Adilson Orlando
1 shared publication- Felipe Tecchio Borsoi
Bioflavors and Bioactive Compounds Laboratory, Department of Food Science and Nutrition (DECAN), School of Food Engineering (FEA), University of Campinas (UNICAMP), Monteiro Lobato Street 80, Campinas 13083-862, São Paulo, Brazil
1 shared publication Grasieli Beloni de Melo
1 shared publication
Latest Publications
- 9 September 2023
- Published by Elsevier in Food Bioscience
- Vol. 56
The emerging importance of NAD+ metabolome for nutrition and food sciences: A bibliometric analysis
- 9 September 2023
- Published by Elsevier in Food Bioscience
- Vol. 56
The emerging importance of NAD+ metabolome for nutrition and food sciences: A bibliometric analysis
- 5 June 2023
- Published by Springer Nature in Current Nutrition Reports
- Vol. 12 (3) , 445-464
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
Purpose of Review NAD+ is a vital molecule that takes part as a redox cofactor in several metabolic reactions besides being used as a substrate in important cellular signaling in regulation pathways for energetic, genotoxic, and infectious stress. In stress conditions, NAD+ biosynthesis and levels decrease as well as the activity of consuming enzymes rises. Dietary precursors can promote NAD+ biosynthesis and increase intracellular levels, being a potential strategy for reversing physiological decline and preventing diseases. In this review, we will show the biochemistry and metabolism of NAD+ precursors NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide), the latest findings on their beneficial physiological effects, their interplay with gut microbiota, and the future perspectives for research in nutrition and food science fields. Recent Findings NMN and NR demonstrated protect against diabetes, Alzheimer disease, endothelial dysfunction, and inflammation. They also reverse gut dysbiosis and promote beneficial effects at intestinal and extraintestinal levels. NR and NMN have been found in vegetables, meat, and milk, and microorganisms in fermented beverages can also produce them. Summary NMN and NR can be obtained through the diet either in their free form or as metabolites derivate from the digestion of NAD+. The prospection of NR and NMN to find potential food sources and their dietary contribution in increasing NAD+ levels are still an unexplored field of research. Moreover, it could enable the development of new functional foods and processing strategies to maintain and enhance their physiological benefits, besides the studies of new raw materials for extraction and biotechnological development.
- 5 June 2023
- Published by Springer Nature in Current Nutrition Reports
- Vol. 12 (3) , 445-464
NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health
Purpose of Review NAD+ is a vital molecule that takes part as a redox cofactor in several metabolic reactions besides being used as a substrate in important cellular signaling in regulation pathways for energetic, genotoxic, and infectious stress. In stress conditions, NAD+ biosynthesis and levels decrease as well as the activity of consuming enzymes rises. Dietary precursors can promote NAD+ biosynthesis and increase intracellular levels, being a potential strategy for reversing physiological decline and preventing diseases. In this review, we will show the biochemistry and metabolism of NAD+ precursors NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide), the latest findings on their beneficial physiological effects, their interplay with gut microbiota, and the future perspectives for research in nutrition and food science fields. Recent Findings NMN and NR demonstrated protect against diabetes, Alzheimer disease, endothelial dysfunction, and inflammation. They also reverse gut dysbiosis and promote beneficial effects at intestinal and extraintestinal levels. NR and NMN have been found in vegetables, meat, and milk, and microorganisms in fermented beverages can also produce them. Summary NMN and NR can be obtained through the diet either in their free form or as metabolites derivate from the digestion of NAD+. The prospection of NR and NMN to find potential food sources and their dietary contribution in increasing NAD+ levels are still an unexplored field of research. Moreover, it could enable the development of new functional foods and processing strategies to maintain and enhance their physiological benefits, besides the studies of new raw materials for extraction and biotechnological development.