Leonardo Mendolicchio

Background/Objectives: Existing literature has consistently identified perfectionism as a core feature of anorexia nervosa (AN). However, much of the research has focused primarily on its association with eating disorder-related symptoms. At the same time, less attention has been paid to understanding how perfectionism affects the overall psychological functioning of individuals with eating disorders, and in particular AN. The present study aimed at investigating the association between perfectionism and both eating disorder-specific symptomatology and general psychological symptoms in a sample of young adult Italian women diagnosed with AN. Methods: Thirty-five Italian females diagnosed with AN (mean age ± SD: 21.9 ± 4.18 years; mean body mass index: body mass index ± SD: 14.5 ± 1.77 kg/m²) were consecutively recruited at the Division of Eating and Nutrition Disorders, Istituto Auxologico Italiano, IRCCS, Piancavallo-Verbania, a third-level clinical centre for the rehabilitation of obesity and eating disorders located in northern Italy. Once informed about the research, screened for inclusion/exclusion criteria, and enrolled, participants were asked to complete the Eating Disorder Inventory—third edition, the Symptoms Checklist-90 revised, and the Frost Multidimensional Perfectionism Scale to collect demographic and clinical variables of interest for the study. Three hierarchical linear regression models were tested to explore the role of perfectionism in both eating disorder-specific symptomatology and general psychological symptoms. Results: The analyses showed a significant influence of perfectionism in all tested models, suggesting that perfectionism was significantly associated with both eating disorder-specific symptomatology and general psychological symptoms in a sample of young adult Italian women diagnosed with AN. Conclusions: The findings of this study provide further support for the role of perfectionism in the psychopathology of eating disorders, particularly among young adult women with AN. Consistent with prior research, perfectionism was associated with both disorder-specific symptoms and broader psychological symptoms. Notably, its association remained robust even after controlling for key variables such as age and body mass index, underscoring its potential as an independent risk factor.

Background/Objectives: Anorexia nervosa (AN) is marked by cognitive deficits, particularly reduced mental flexibility and weak central coherence, which may sustain the core psychopathological symptoms. While cognitive remediation therapy (CRT) has shown efficacy in improving these cognitive processes in AN, evidence on computer-based CRT remains limited. This study aims to evaluate the feasibility and efficacy of integrating computer-assisted cognitive remediation therapy (CA-CRT) into standard nutritional rehabilitation (treatment as usual, TAU) to improve the targeted cognitive and psychological parameters among inpatients with AN in a more personalized and scalable way. Methods: A multicenter randomized controlled trial (RCT) will be conducted. At least 54 participants with a diagnosis of AN will be recruited at each site and randomized into either the experimental or control group after initial screening. The intervention will last five weeks and include 15 individual CA-CRT sessions alongside 10 individual CR sessions, delivered in addition to standard care. The primary and secondary outcomes will be assessed at the end of the intervention to evaluate the changes in cognitive flexibility, central coherence, and psychological functioning. Results: Participants receiving CA-CRT are expected to develop more flexible and integrated thinking styles and achieve greater improvements in clinical outcomes compared to those receiving standard care alone, supporting a more personalized therapeutic approach. Conclusions: These findings would underscore the feasibility and clinical value of incorporating CA-CRT into standard inpatient treatment for AN. By specifically targeting cognitive inflexibility and poor central coherence in a scalable, individualized format, CA-CRT may enhance treatment effectiveness and support the development of patient-centered interventions tailored to the cognitive profiles of individuals with AN.

Perceptual illusions of having extra body parts offer an experimental method to investigate the limits of body perception. It is well established that the illusory perception of an artificial hand as one’s own is dependent on spatial congruency. That is, the seen hand needs to be in a posture congruent with the actual hand. In this study, we aimed to investigate how constrained the representation of a supernumerary body part is by systematically varying the perceived rotation of an illusory sixth finger. Surprisingly, participants felt a sixth finger on their hand consistently for all induced orientations of finger extension and abduction (0°, 90°, 135°, 180°). The illusion showed no apparent decrease with increased induced rotation of the extra finger. We also measured the perceived orientation of the sixth finger, and our results show that participants felt an extended and an abducted sixth finger increasingly more rotated as the induced rotation also increased, while feeling their actual little finger in a normal position. Our results indicate that one can feel a supernumerary finger in an incongruent spatial location from one’s actual fingers and hand, to an extent of 180° of extension (finger up) and 180° of abduction (finger to the side). We therefore propose that the representation of the supernumerary finger has a strong independence from the actual finger and hand-frame reference.

Introduction. Anorexia nervosa severely impacts the physical body and mental body (i.e., body image). In this retrospective study, we investigated the relationship between the perceived body image and body composition in women with anorexia nervosa. Specifically, we aimed to verify what components (i.e., weight, body composition, and micronutrients) may predict a higher number of symptoms of negative body image in this clinical condition. Methods. Weight status and body composition, including the expressions of vitamins, and body image concerns were measured in a sample of 112 women with anorexia nervosa (age in years M = 26.78; SD = 12; range = 14–67). Results. According to the regression analysis, a higher skeletal muscle mass and a higher concentration of vitamin B6 seemed to predict a higher number of symptoms of negative body image in our sample. Conclusions. This study pointed out muscle mass and the concentration of vitamin B6 as involved in the psychological expression of body image concerns in anorexia nervosa, especially at the beginning of the disease. Thus, we may suggest including and monitoring these parameters in routine care for anorexia nervosa.

Background: There is growing support for considering Dance Movement Therapy (DMT) as an effective approach to improving physical and psychological symptoms in eating disorders (ED), but additional evidence is needed. The current study aims to investigate the effectiveness of a DMT intervention for inpatients with ED during an in-hospital rehabilitation program for ED in reducing emotion dysregulation and alexithymia and improving interoceptive awareness. Methods: Forty-nine consecutive inpatient young women with ED (aged between 18 and 34 years) recruited from a clinical center for the rehabilitation of obesity and ED received four group sessions of DMT intervention. All participants completed the Difficulties in Emotion Regulation Scale (DERS), the Toronto Alexithymia Scale (TAS), and the Multidimensional Assessment of Interoceptive Awareness Scale (MAIA) before (Time 0) and after the intervention (Time 1). Paired-sample t-tests were run to assess differences between Time 0 to Time 1. Results: From pre-to-post interventions, there was a significant reduction in the means of all of the subscales of DERS, suggesting an improvement in emotion regulation competencies, with the only exception for difficulties in awareness that increased (p = 0.016). We also found a significant reduction in alexithymia, as proved by significant differences in all of the subscales and the total score of TAS (p < 0.001), and significant improvements in interoceptive awareness as suggested by increased scores of the noticing (p = 0.043), emotional awareness (p < 0.001), body listening (p < 0.001), and trusting (p < 0.001) subscales of MAIA. Conclusion: Overall, our results point towards the efficacy of dance/movement in reducing symptoms of eating disorders. Our findings also suggest that dancing can be considered a useful intervention to increase emotional regulation, reduce alexithymia, and enhance interoceptive awareness.

Anorexia nervosa (AN) and bulimia nervosa (BN) are eating diseases characterized by extreme eating behaviours impacting both mental and physical health. Aberrant musculoskeletal adaptations due to malnutrition affect motor abilities such as postural control and gait. To date, limited data is available with regards to gait symmetry in AN and BN. The aim of this study was to characterize inter-limb asymmetry during gait in two cohorts affected by AN and BN, respectively, using the synchronized cyclograms and to compare it with a healthy weight group. A total of 14 AN, 17 BN, and 11 healthy-weight females were assessed via 3D gait analysis. Gait spatio-temporal parameters were computed together with angle–angle diagrams, which were characterized in terms of their geometric features. Individuals with AN and BN were characterized by reduced speed and cadence and an abnormal increase in the duration of the double support phase with respect to the healthy controls. With respect to inter-limb symmetry, asymmetries were detected in both groups, with individuals with BN exhibiting significantly larger cyclogram areas at the hip joint with respect to the other groups (323.43 degrees² vs. 253.74 degrees² vs. 136.37 degrees²) and significantly higher orientation angle and Trend Symmetry at both knee and ankle joint. The cyclogram analysis suggests the presence of an altered gait symmetry in individuals with BN. In the AN group, it is possible to observe a similar trend; however, this is not statistically significant. Overall, the findings of this study may provide a novel perspective on the motor control dysfunction linked to eating disorders and aid clinicians in selecting a suitable rehabilitation scheme targeted at enhancing motor stability and control.

The aim of this systematic review was to synthesise the impact of the COVID-19 pandemic on binge eating disorder (BED) the new onset and course. Inclusion criteria: original articles and BED diagnosis; and the main outcomes: relationships between the COVID-19 pandemic and the new onset/clinical changes in BED, and specific results for BED. Exclusion criteria: mixed/inaccurate diagnoses and articles not written in English. We searched four databases and one registry until 5 May 2023. The quality appraisal was conducted using the Effective Public Health Practice Project (EPHPP) tool. Twelve studies with 4326 participants were included. All studies were observational with nine cross-sectional and three longitudinal. Four of the included studies investigated new-onset BED, while eight examined the BED clinical course of patients with a previous diagnosis. With the exception of one study, the available literature indicates both an increase in BED diagnoses and a clinical worsening during COVID-19. Major limitations include study quality (weak-to-moderate) and high heterogeneity in terms of pandemic phase, population, geographical areas, and psychometric tools. Our findings indicate that BED patients are particularly vulnerable to events characterised by social distancing and over-worry, and should be, therefore, carefully monitored. Further studies are needed to corroborate our findings, implement preventive strategies, and promote personalised treatments. PROSPERO registration number: CRD42023434106