Tran Hong Tram

Background: Mixing vaccines was proposed as a solution to tackle supply chain interruptions during the crisis of the COVID-19 pandemic. This study aimed to investigate the safety of mixing COVID-19 vaccines for a booster dose in Hanoi, Vietnam. Method: A cross-sectional study was conducted via a telephone-based interview to identify the adverse events following COVID-19 vaccination among 719 participants in Hanoi, Vietnam. Results: In total, 45.76% of participants experienced at least one adverse event following two doses of the COVID-19 vaccine. Most of the adverse events were local effects with mild symptoms such as fever, headache, muscle pain, and/or pain at the site. In general, matching two doses in the same vaccines was not associated with the adverse events as compared to mixing vaccines (OR = 1.43, 96%CI: 0.93–2.2), except matching two doses of Pfizer (OR = 2.25, 95%CI: 1.33–3.82). Conclusion: The findings of this study suggest the overall safety of mixed vaccination. In light of the vaccine shortage, mixing vaccinations for COVID-19 prevention is a good solution. Further studies with larger cohorts and investigating immunity following mixing vaccines are needed to elucidate the mechanism.

The role of sleep deprivation in affecting on social behavior like aggression is not yet fully understood. This study shows how interactions between social factors affect on sleep and the aggressive behavior of adolescents. Data collected from 8,115 survey participants were analyzed by the linear regression model and the mediation model to find links between social factors, sleep deprivation and aggressive behavior by controlling key variables. The results of study show a significant increase in the aggressive behavior of young people who lack of sleep, abuse on-screen time, and are influenced by other factors like age, gender and family. Conclusions: The results demonstrate that on-screen time is an important factor that affects aggressive behavior through sleep deprivation.