Kosuke Otake
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Kosuke Otake has a total of 15 co-authors. Here are the top co-authors by number of shared publications:
- Atsuo Nakamura
Emergency and Critical Care Medicine, Iizuka City Hospital, Iizuka, JPN
1 shared publication - Chie Tanaka
Department of Emergency and Critical Care Medicine, Nippon Medical School Tama Nagayama Hospital, Tokyo, Japan
1 shared publication - Hiroshi Kamijo
Department of Emergency and Critical Care Medicine, Shinshu University School of Medicine, Nagano, Japan
1 shared publication - Hiroyasu Ishikura
Department of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan
1 shared publication - Hiroyuki Ohbe
Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, Japan
1 shared publication J-STAD (Japan Sepsis Treatment and Diagnosis) Study Group
1 shared publication
Latest Publications
- Open Access
- 11 December 2024
- Published by Springer Nature in Cureus
- Vol. 16 (12) , e75528
A Treatment Strategy for Severe Legionella Pneumonia Using Veno-Venous Extracorporeal Membrane Oxygenation
Legionella pneumophila can cause acute respiratory distress syndrome (ARDS), which often requires intense ventilatory management. L. pneumophila is an aerobic bacterium that prefers a high-oxygen environment. However, existing treatment strategies, including veno-venous extracorporeal membrane oxygenation (V-V ECMO), have not considered the pathogen's preference for high-oxygen environments. Herein, we report two cases of patients with severe legionella pneumonia treated with V-V ECMO. The treatment strategy in these two cases was to maintain the lowest possible oxygen concentrations to inhibit the activity of L. pneumophila. This strategy was successful, indicating that V-V ECMO may be useful to improve outcomes in severe ARDS caused by L. pneumophila, especially when introduced earlier.
- 11 December 2024
- Published by Springer Nature in Cureus
- Vol. 16 (12) , e75528
Open AccessA Treatment Strategy for Severe Legionella Pneumonia Using Veno-Venous Extracorporeal Membrane Oxygenation
Legionella pneumophila can cause acute respiratory distress syndrome (ARDS), which often requires intense ventilatory management. L. pneumophila is an aerobic bacterium that prefers a high-oxygen environment. However, existing treatment strategies, including veno-venous extracorporeal membrane oxygenation (V-V ECMO), have not considered the pathogen's preference for high-oxygen environments. Herein, we report two cases of patients with severe legionella pneumonia treated with V-V ECMO. The treatment strategy in these two cases was to maintain the lowest possible oxygen concentrations to inhibit the activity of L. pneumophila. This strategy was successful, indicating that V-V ECMO may be useful to improve outcomes in severe ARDS caused by L. pneumophila, especially when introduced earlier.
- Open Access
- 6 February 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (4) , 1273
Sepsis-Associated Delirium: A Narrative Review
Delirium is characterized by an acutely altered mental status accompanied by reductions in cognitive function and attention. Delirium in septic patients, termed sepsis-associated delirium (SAD), differs in several specific aspects from the other types of delirium that are typically encountered in intensive care units. Since sepsis and delirium are both closely associated with increased morbidity and mortality, it is important to not only prevent but also promptly diagnose and treat SAD. We herein reviewed the etiology, pathogenesis, risk factors, prevention, diagnosis, treatment, and prognosis of SAD, including coronavirus disease 2019 (COVID-19)-related delirium. Delirium by itself not only worsens long-term prognosis, but it is also regarded as an important factor affecting the outcome of post-intensive care syndrome. In COVID-19 patients, the difficulties associated with adequately implementing the ABCDEF bundle (Assess, prevent, and manage pain; Both spontaneous awakening and breathing trials: Choice of analgesia and sedation; Delirium assess, prevent, and manage; Early mobility and exercise; Family engagement/empowerment) and the need for social isolation are issues that require the development of conventional care for SAD.
- 6 February 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (4) , 1273
Open AccessSepsis-Associated Delirium: A Narrative Review
Delirium is characterized by an acutely altered mental status accompanied by reductions in cognitive function and attention. Delirium in septic patients, termed sepsis-associated delirium (SAD), differs in several specific aspects from the other types of delirium that are typically encountered in intensive care units. Since sepsis and delirium are both closely associated with increased morbidity and mortality, it is important to not only prevent but also promptly diagnose and treat SAD. We herein reviewed the etiology, pathogenesis, risk factors, prevention, diagnosis, treatment, and prognosis of SAD, including coronavirus disease 2019 (COVID-19)-related delirium. Delirium by itself not only worsens long-term prognosis, but it is also regarded as an important factor affecting the outcome of post-intensive care syndrome. In COVID-19 patients, the difficulties associated with adequately implementing the ABCDEF bundle (Assess, prevent, and manage pain; Both spontaneous awakening and breathing trials: Choice of analgesia and sedation; Delirium assess, prevent, and manage; Early mobility and exercise; Family engagement/empowerment) and the need for social isolation are issues that require the development of conventional care for SAD.