Yu-Chun Lin
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Yu-Chun Lin has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Ching-Yu Huang
Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County, Taiwan
1 shared publication - En-Wei Hsing
Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County 35053, Taiwan
1 shared publication - Fang-Hsuean Liao
Institute of Biomedical Engineering and Nanomedicine National Health Research Institutes (NHRI) Zhunan Town Miaoli County 35053 Taiwan
1 shared publication - Jr-Wen Shui
Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas 77030, USA
1 shared publication - Tse-Hua Tan
Immunology Research Center, National Health Research Institutes, 35 Keyan Road, Zhunan, 35053, Taiwan.
1 shared publication - Wan-Yi Hsiao
Immunology Research Center, National Health Research Institutes, Zhunan, Miaoli County 35053, Taiwan
1 shared publication
Latest Publications
- Open Access
- 7 May 2014
- Published by Springer Nature in Cell & Bioscience
- Vol. 4 (1) , 25
Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity
Protein phosphates 4 (PP4), encoded by the ppp4c gene, is a ubiquitously expressed phosphatase that has been implicated in the regulation of cytokine signaling and lymphocyte survival; recent reports suggest that PP4 may be involved in pre-TCR signaling and B cell development. However, whether PP4 also modulates the functions of peripheral T cells has not been investigated due to the lack of a suitable in vivo model. Treg cells are a specialized subset of CD4 helper T cells that can suppress the proliferation of activated effector T cells. In the absence of this negative regulation, autoimmune syndromes and inflammatory diseases, such as human Crohn’s disease, will arise.
- 7 May 2014
- Published by Springer Nature in Cell & Bioscience
- Vol. 4 (1) , 25
Open AccessProtein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity
Protein phosphates 4 (PP4), encoded by the ppp4c gene, is a ubiquitously expressed phosphatase that has been implicated in the regulation of cytokine signaling and lymphocyte survival; recent reports suggest that PP4 may be involved in pre-TCR signaling and B cell development. However, whether PP4 also modulates the functions of peripheral T cells has not been investigated due to the lack of a suitable in vivo model. Treg cells are a specialized subset of CD4 helper T cells that can suppress the proliferation of activated effector T cells. In the absence of this negative regulation, autoimmune syndromes and inflammatory diseases, such as human Crohn’s disease, will arise.