Kihak Lee

Microneedles (MNs) have emerged as a promising tool for pain-free drug delivery, offering an alternative to traditional syringe-based methods. Among various types of MNs, dissolving microneedles fabricated from hyaluronic acid (HA) have gained attention due to their biocompatibility and ability to deliver drugs with minimal discomfort. However, conventional HA MN fabrication techniques often limit needle lengths to a few hundred micrometers, which is insufficient for deeper drug penetration. This study introduces a novel fabrication method using bidirectional drawing lithography to extend the length of HA-based MNs. By adjusting the viscosity of HA solutions and employing a controlled pulling process, we demonstrate the feasibility of producing MNs with lengths ranging from millimeters to micrometers. An average height of 15 mm and tip diameters of approximately 80 μm were successfully produced. This advancement enhances the potential of HA MNs for transdermal drug delivery and interstitial fluid sampling.

In this study, we developed a cost-effective and rapid method for fabricating force-sensing resistor (FSR) sensors as an alternative to commercial force sensors. Our aim was to achieve performance characteristics comparable to existing commercial products while significantly reducing costs and fabrication time. We analyzed the material composition of two widely used commercial force sensors: Interlink FSR-402 and Flexiforce A201-1. Based on this analysis, we selected 4B and 9B pencils, which contain high concentrations of graphite, and silicone sealant to replicate these material properties. The fabrication process involved creating piezoresistive sheets by shading A4 copy paper with 4B and 9B pencils to form a uniform layer of graphite. Additionally, we prepared a mixture of 9B pencil lead powder and silicone sealant, ensuring a consistent application on the paper substrate. Measurement results indicated that the force sensor fabricated using a mixture of 9B pencil powder and silicone sealant exhibited electrical and mechanical characteristics closely resembling those of commercial sensors. Load tests revealed that the hand-made sensors provided a proportional voltage output in response to increasing and decreasing loads, similar to commercial FSR sensors. These results suggest that our fabrication method can produce reliable and accurate FSR sensors suitable for various applications, including wearable technology, robotics, and force-sensing interfaces. Overall, this study demonstrates the potential for creating cost-effective and high-performance FSR sensors using readily available materials and simple fabrication techniques.

In this study, we thoroughly analyzed the linearity and repeatability of force-sensing resistor (FSR) sensors through static load tests to ensure their reliability. The novelty of this research lies in its comprehensive evaluation and direct comparison of two widely used FSR sensors, i.e., Flexiforce A201-1 and Interlink FSR-402, under various loading conditions by employing a robust calibration methodology. This study provides detailed insights into the sensors’ performances, offering practical calibration equations that enhance measurement precision and reliability, which have not been extensively documented in previous studies. Our results demonstrate that the linearity of thin film FSR sensors is highly accurate, closely resembling a straight line. We employed M1 Class weights, applying loads ranging from 20 g to 300 g. The resistance of the FSR sensors, which varies with the applied load, was measured using a voltage divider circuit and an analog-to-digital converter of a microcontroller. MATLAB was used to calculate the average output voltage for each applied load and fixed resistance. Additionally, we examined the relationships among load, FSR sensor resistance, and conductivity. Our research indicates that with precise calibration, thin film FSR sensors can be highly reliable for force measurement applications.

In this context, the open-circuit voltage generated by either poly (vinylidene fluoride) or PVDF and ZnO composite sample before being enhanced to 4.2 V compared to 1.2 V for the samples of pure PVDF. The spin coating method was used to create a composite film, which served as a piezoelectric nanogenerator (PNG). Zinc oxide (ZnO) nanoparticles and PVDF serve as the matrix for the coating structure. Thin films were created that employed the spin coating method to achieve the desired results of ZnO’s non-brittle outcome and piezoelectric characteristics, as well as PVDF for use in self-powered devices. Scanning electron microscopy (SEM), X-ray diffraction (XRD), and fourier transform infrared (FT-IR) were used to evaluate the properties of these formations. The electrical properties of the film were measured using an oscilloscope. Results indicated that by adding ZnO nanoparticles to the PVDF samples, piezoelectric capabilities were enhanced compared to samples containing PVDF only. These results point to promising uses for various wearable devices, such as water strider robot systems and self-operating equipment.