Caspar W. J. Hulleman
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Caspar W. J. Hulleman has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Frank-Christiaan Wagenaar
European Knee Society (EKS), Europe
1 shared publication - Gijs van Hellemondt
Department of Orthopaedic Surgery, Sint Maartenskliniek, Nijmegen, Netherlands
1 shared publication - Jon H. M. Goosen
Department of Orthopedic Surgery, Sint Maartenskliniek, 6574 NA Ubbergen, Gelderland, The Netherlands
1 shared publication - Karin Veerman
Department of Internal Medicine, Sint Maartenskliniek, Hengstdal 3, 6574NA Ubbergen, the Netherlands
1 shared publication - Tommy S. de Windt
Orthopedisch Centrum Oost Nederland, Orthopedic Center, 7555 DL Hengelo, The Netherlands
1 shared publication
Latest Publications
- Open Access
- 31 July 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (15) , 5026
Debridement, Antibiotics and Implant Retention: A Systematic Review of Strategies for Treatment of Early Infections after Revision Total Knee Arthroplasty
Goal: The purpose of this review is to provide a systematic and comprehensive overview of the available literature on the treatment of an early prosthetic joint infection (PJI) after revision total knee arthroplasty (TKA) and provide treatment guidelines. Methods: This systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The search was conducted using the electronic databases of PubMed, Trip, Cochrane, Embase, LILACS and SciElo. After the inclusion of the relevant articles, we extracted the data and results to compose a treatment algorithm for early and acute PJI after revision TKA. Results: After applying the in- and exclusion criteria, seven articles were included in this systematic review focusing on debridement, antibiotics and implant retention (DAIR) for PJI following revision TKA, of which one was prospective and six were retrospective. All studies were qualified as level IV evidence. Conclusions: The current literature suggests that DAIR is a valid treatment option for early infections after revision TKA with success rates of 50–70%. Repeat DAIR shows success rates of around 50%. Further research should be aimed at predicting successful (repeat/two-stage) DAIRs in larger study populations, antibiotic regimes and the cost effectiveness of a second DAIR after revision TKA.
- 31 July 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (15) , 5026
Open AccessDebridement, Antibiotics and Implant Retention: A Systematic Review of Strategies for Treatment of Early Infections after Revision Total Knee Arthroplasty
Goal: The purpose of this review is to provide a systematic and comprehensive overview of the available literature on the treatment of an early prosthetic joint infection (PJI) after revision total knee arthroplasty (TKA) and provide treatment guidelines. Methods: This systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. The search was conducted using the electronic databases of PubMed, Trip, Cochrane, Embase, LILACS and SciElo. After the inclusion of the relevant articles, we extracted the data and results to compose a treatment algorithm for early and acute PJI after revision TKA. Results: After applying the in- and exclusion criteria, seven articles were included in this systematic review focusing on debridement, antibiotics and implant retention (DAIR) for PJI following revision TKA, of which one was prospective and six were retrospective. All studies were qualified as level IV evidence. Conclusions: The current literature suggests that DAIR is a valid treatment option for early infections after revision TKA with success rates of 50–70%. Repeat DAIR shows success rates of around 50%. Further research should be aimed at predicting successful (repeat/two-stage) DAIRs in larger study populations, antibiotic regimes and the cost effectiveness of a second DAIR after revision TKA.