Chi-Chia Hsieh
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Chi-Chia Hsieh has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Chia-Chun Hsia
Department of Education, China Medical University Hospital, Taichung 404327, Taiwan
1 shared publication - Nien-En Ku
Department of Education, China Medical University Hospital, Taichung 404327, Taiwan
1 shared publication - Shu-Jui Kuo
School of Medicine, China Medical University, Taichung
1 shared publication - Sung-Hsiung Chen
Department of Orthopedic Surgery, College of Medicine, Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 833401, Taiwan
1 shared publication - Tzu-Ju Hsu
Management Office for Health Data, China Medical University Hospital, Taichung 404327, Taiwan
1 shared publication - Yi-Hsiu Fu
Department of Education, Taichung Veterans General Hospital, Taichung 407219, Taiwan
1 shared publication
Latest Publications
- Open Access
- 3 August 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (15) , 5102
The Impact of Chronic Pancreatitis on the Occurrences of Human Cancers: Real-World Data
Chronic pancreatitis (CP) may induce systemic inflammation, potentially increasing cancer susceptibility. However, the link between CP and extra-pancreatic cancer remains underexplored. Employing Taiwanese National Health Insurance Database data from 2000 to 2017, we compared 5394 CP patients with 21,576 non-CP individuals through propensity score matching. CP patients exhibited a significantly higher cancer risk (adjusted hazard ratio (aHR) of 1.32 for females and 1.68 for males) and cumulative incidence (p < 0.001) compared to non-CP individuals. CP showed notable associations with pancreatic (aHR = 3.51), liver (aHR = 1.62), stomach (aHR = 2.01), and other cancers (aHR = 2.09). In terms of liver cancer, CP was significantly associated with patients without viral hepatitis, regardless of gender (aHR = 2.01 for women; aHR = 1.54 for men). No significant cancer occurrences were observed within the first year following CP diagnosis. Pancreatic or liver cancer developed in approximately half of CP patients within 2–3 years, while gastric cancer in male CP patients predominantly occurred around the fifth year after diagnosis. These findings inform potential cancer-screening plans for CP patients.
- 3 August 2023
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 12 (15) , 5102
Open AccessThe Impact of Chronic Pancreatitis on the Occurrences of Human Cancers: Real-World Data
Chronic pancreatitis (CP) may induce systemic inflammation, potentially increasing cancer susceptibility. However, the link between CP and extra-pancreatic cancer remains underexplored. Employing Taiwanese National Health Insurance Database data from 2000 to 2017, we compared 5394 CP patients with 21,576 non-CP individuals through propensity score matching. CP patients exhibited a significantly higher cancer risk (adjusted hazard ratio (aHR) of 1.32 for females and 1.68 for males) and cumulative incidence (p < 0.001) compared to non-CP individuals. CP showed notable associations with pancreatic (aHR = 3.51), liver (aHR = 1.62), stomach (aHR = 2.01), and other cancers (aHR = 2.09). In terms of liver cancer, CP was significantly associated with patients without viral hepatitis, regardless of gender (aHR = 2.01 for women; aHR = 1.54 for men). No significant cancer occurrences were observed within the first year following CP diagnosis. Pancreatic or liver cancer developed in approximately half of CP patients within 2–3 years, while gastric cancer in male CP patients predominantly occurred around the fifth year after diagnosis. These findings inform potential cancer-screening plans for CP patients.