Krishna Pal Singh
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Research Interests
Krishna Pal Singh has a total of 19 co-authors. Here are the top co-authors by number of shared publications:
- Anu Puri
Basic Research Laboratory, Centre for Cancer Research, National Cancer Institute-Frederick, National Institute of Health, Post Office Box. Building 469, Room No. 216A, Frederick, MD 21702-1201, USA
1 shared publication - Anuj Nehra
Bio-Nanotechnology Research Laboratory, Biophysics Unit, College of Basic Science & Humanities, G.B. Pant University of Agriculture and Technology, Pantnagar 263145, Uttarakhand, India
1 shared publication Anuj Rana
Department of Microbiology, College of Basic Sciences and Humanities, Chaudhary Charan Singh Haryana Agricultural University (CCS HAU), Hisar, India
1 shared publication- Ashutosh Sharma
Department of Materials Science and Engineering, Ajou University, Suwon 16499, Republic of Korea
1 shared publication - Brajesh Kumar
Department of Computer Science & Information Technology, MJP Rohilkhand University, Bareilly, India
1 shared publication - Krishan Kumar
Department of Computer Science, Gurukula Kangri Vishwavidyalaya, Haridwar, India
1 shared publication
Latest Publications
- Open Access
- 20 October 2026
- Published by Springer Nature in Discover Nano
- Vol. 21 (1) , 535
Current understanding and future scope of nanotechnology enabled epidermal care using cosmetics and cosmeceuticals
- 20 October 2026
- Published by Springer Nature in Discover Nano
- Vol. 21 (1) , 535
Open AccessCurrent understanding and future scope of nanotechnology enabled epidermal care using cosmetics and cosmeceuticals
- 4 October 2023
- Published by Springer Nature in The Visual Computer
- Vol. 40 (6) , 4457-4471
Paddy yield prediction based on 2D images of rice panicles using regression techniques
- 4 October 2023
- Published by Springer Nature in The Visual Computer
- Vol. 40 (6) , 4457-4471
Paddy yield prediction based on 2D images of rice panicles using regression techniques
- Open Access
- 15 February 2023
- Published by MDPI AG in Pharmaceutics
- Vol. 15 (2) , 649
Chlorambucil-Loaded Graphene-Oxide-Based Nano-Vesicles for Cancer Therapy
In this study, the authors have designed biocompatible nano-vesicles using graphene oxide (GO) for the release of chlorambucil (CHL) drugs targeting cancerous cells. The GO sheets were first sulfonated and conjugated with folic acid (FA) molecules for controlled release and high loading efficiency of CHL. The chlorambucil (CHL) drug loading onto the functionalized GO surface was performed through π-π stacking and hydrophobic interactions with the aromatic planes of GO. The drug loading and “in vitro” release from the nano-vesicles at different pH were studied. The average particle size, absorption, and loading efficiency (%) of FA-conjugated GO sheets (CHL-GO) were observed to be 300 nm, 58%, and 77%, respectively. The drug release study at different pH (i.e., 7.4 and 5.5) showed a slight deceleration at pH 7.4 over pH 5.5. The amount of drug released was very small at pH 7.4 in the first hour which progressively increased to 24% after 8 h. The rate of drug release was faster at pH 5.5; initially, 16% to 27% in the first 3 h, and finally it reached 73% after 9 h. These observations indicate that the drug is released more rapidly at acidic pH with a larger amount of drug-loading ability. The rate of drug release from the CHL-loaded GO was 25% and 75% after 24 h. The biotoxicity study in terms of % cell viability of CHL-free and CHL-loaded GO against human cervical adenocarcinoma cell line was found to have lower cytotoxicity of CHL-loaded nano-vesicles (IC50 = 18 μM) as compared to CHL-free (IC50 = 8 μM). It is concluded that a high drug-loading efficiency and controlled release with excellent biotoxicity of CHL-GO offers an excellent application in the biomedical field.
- 15 February 2023
- Published by MDPI AG in Pharmaceutics
- Vol. 15 (2) , 649
Open AccessChlorambucil-Loaded Graphene-Oxide-Based Nano-Vesicles for Cancer Therapy
In this study, the authors have designed biocompatible nano-vesicles using graphene oxide (GO) for the release of chlorambucil (CHL) drugs targeting cancerous cells. The GO sheets were first sulfonated and conjugated with folic acid (FA) molecules for controlled release and high loading efficiency of CHL. The chlorambucil (CHL) drug loading onto the functionalized GO surface was performed through π-π stacking and hydrophobic interactions with the aromatic planes of GO. The drug loading and “in vitro” release from the nano-vesicles at different pH were studied. The average particle size, absorption, and loading efficiency (%) of FA-conjugated GO sheets (CHL-GO) were observed to be 300 nm, 58%, and 77%, respectively. The drug release study at different pH (i.e., 7.4 and 5.5) showed a slight deceleration at pH 7.4 over pH 5.5. The amount of drug released was very small at pH 7.4 in the first hour which progressively increased to 24% after 8 h. The rate of drug release was faster at pH 5.5; initially, 16% to 27% in the first 3 h, and finally it reached 73% after 9 h. These observations indicate that the drug is released more rapidly at acidic pH with a larger amount of drug-loading ability. The rate of drug release from the CHL-loaded GO was 25% and 75% after 24 h. The biotoxicity study in terms of % cell viability of CHL-free and CHL-loaded GO against human cervical adenocarcinoma cell line was found to have lower cytotoxicity of CHL-loaded nano-vesicles (IC50 = 18 μM) as compared to CHL-free (IC50 = 8 μM). It is concluded that a high drug-loading efficiency and controlled release with excellent biotoxicity of CHL-GO offers an excellent application in the biomedical field.