Shengyou Shi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Shengyou Shi has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Chongbing Zhou
School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408100, China
1 shared publication - Gangjun Luo
School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408100, China
1 shared publication - Si Tan
School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408100, China
1 shared publication - Wenfeng Li
School of Life Science and Biotechnology, Yangtze Normal University, Chongqing 408100, China
1 shared publication - Xiaobo Ding
Luzhou Academy of Agricultural Sciences, Luzhou 646000, China
1 shared publication - Yuping Luo
School of Advanced Agriculture and Bioengineering, Yangtze Normal University, Chongqing 408100, China
1 shared publication
Latest Publications
- Open Access
Polyphenol Profile, Antioxidant Activity, and Hypolipidemic Effect of Longan Byproducts
Longan, a popular fruit in Asia, has been used in traditional Chinese medicine to treat several diseases for centuries. Recent studies have indicated that longan byproducts are rich in polyphenols. The aim of this study was to analyze the phenolic composition of longan byproduct polyphenol extracts (LPPE), evaluate their antioxidant activity in vitro, and investigate their regulating effect on lipid metabolism in vivo. The results indicated that the antioxidant activity of LPPE was 231.350 ± 21.640, 252.380 ± 31.150, and 558.220 ± 59.810 (mg Vc/g) as determined by DPPH, ABTS, and FRAP, respectively. UPLC-QqQ-MS/MS analysis indicated that the main compounds in LPPE were gallic acid, proanthocyanidin, epicatechin, and phlorizin. LPPE supplementation prevented the body weight gain and decreased serum and liver lipids in high-fat diet-induced-obese mice. Furthermore, RT-PCR and Western blot analysis indicated that LPPE upregulated the expression of PPARα and LXRα and then regulated their target genes, including FAS, CYP7A1, and CYP27A1, which are involved in lipid homeostasis. Taken together, this study supports the concept that LPPE can be used as a dietary supplement in regulating lipid metabolism.
Open AccessPolyphenol Profile, Antioxidant Activity, and Hypolipidemic Effect of Longan Byproducts
Longan, a popular fruit in Asia, has been used in traditional Chinese medicine to treat several diseases for centuries. Recent studies have indicated that longan byproducts are rich in polyphenols. The aim of this study was to analyze the phenolic composition of longan byproduct polyphenol extracts (LPPE), evaluate their antioxidant activity in vitro, and investigate their regulating effect on lipid metabolism in vivo. The results indicated that the antioxidant activity of LPPE was 231.350 ± 21.640, 252.380 ± 31.150, and 558.220 ± 59.810 (mg Vc/g) as determined by DPPH, ABTS, and FRAP, respectively. UPLC-QqQ-MS/MS analysis indicated that the main compounds in LPPE were gallic acid, proanthocyanidin, epicatechin, and phlorizin. LPPE supplementation prevented the body weight gain and decreased serum and liver lipids in high-fat diet-induced-obese mice. Furthermore, RT-PCR and Western blot analysis indicated that LPPE upregulated the expression of PPARα and LXRα and then regulated their target genes, including FAS, CYP7A1, and CYP27A1, which are involved in lipid homeostasis. Taken together, this study supports the concept that LPPE can be used as a dietary supplement in regulating lipid metabolism.