Mateja Peršić

Mateja Peršić

*This is an algorithmically generated author record based on publicly available information.

Current Organizations / Institutes

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Mateja Peršić has a total of 5 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Development of the New Sensor Based on Functionalized Carbon Nanomaterials for Promethazine Hydrochloride Determination

    by Mirela Samardžić, Mateja Peršić, Aleksandar Széchenyi, Marija Jozanović, Iva Pukleš, Mateja Budetić

    Promethazine hydrochloride (PM) is a widely used drug so its determination is important. Solid-contact potentiometric sensors could be an appropriate solution for that purpose due to their analytical properties. The aim of this research was to develop solid-contact sensor for potentiometric determination of PM. It had a liquid membrane containing hybrid sensing material based on functionalized carbon nanomaterials and PM ions. The membrane composition for the new PM sensor was optimized by varying different membrane plasticizers and the content of the sensing material. The plasticizer was selected based on calculations of Hansen solubility parameters (HSP) and experimental data. The best analytical performances were obtained using a sensor with 2-nitrophenyl phenyl ether (NPPE) as the plasticizer and 4% of the sensing material. It had a Nernstian slope (59.4 mV/decade of activity), a wide working range (6.2 × 10−7 M–5.0 × 10−3 M), a low limit of detection (1.5 × 10−7 M), fast response time (6 s), low signal drift (−1.2 mV/h), and good selectivity. The working pH range of the sensor was between 2 and 7. The new PM sensor was successfully used for accurate PM determination in a pure aqueous PM solution and pharmaceutical products. For that purpose, the Gran method and potentiometric titration were used.