Deeksha Bharti
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Deeksha Bharti has a total of 4 co-authors. Here are the top co-authors by number of shared publications:
- Jerusha Stephen
ICAR-Central Institute of Fisheries Education (CIFE), Mumbai 400061, India
1 shared publication - Manjusha Lekshmi
Fish Processing Technology Department, ICAR-Central Institute of Fisheries Education, Mumbai, India
1 shared publication - Manuel F. Varela
Department of Biology, Eastern New Mexico University, Portales, USA
1 shared publication - Sanath Hirekudel Kumar
QC Laboratory, Fish Processing Technology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
1 shared publication
Latest Publications
- Open Access
- 15 May 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (5) , 1448
Inhibition of Multidrug Efflux Pumps Belonging to the Major Facilitator Superfamily in Bacterial Pathogens
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are causative agents of infectious disease, and they thus constitute a serious concern for public health. Of the various bacterial mechanisms for antimicrobial resistance, active efflux is a well-known system that extrudes clinically relevant antimicrobial agents, rendering specific pathogens recalcitrant to the growth-inhibitory effects of multiple drugs. In particular, multidrug efflux pump members of the major facilitator superfamily constitute central resistance systems in bacterial pathogens. This review article addresses the recent efforts to modulate these antimicrobial efflux transporters from a molecular perspective. Such investigations can potentially restore the clinical efficacy of infectious disease chemotherapy.
- 15 May 2023
- Published by MDPI AG in Biomedicines
- Vol. 11 (5) , 1448
Open AccessInhibition of Multidrug Efflux Pumps Belonging to the Major Facilitator Superfamily in Bacterial Pathogens
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are causative agents of infectious disease, and they thus constitute a serious concern for public health. Of the various bacterial mechanisms for antimicrobial resistance, active efflux is a well-known system that extrudes clinically relevant antimicrobial agents, rendering specific pathogens recalcitrant to the growth-inhibitory effects of multiple drugs. In particular, multidrug efflux pump members of the major facilitator superfamily constitute central resistance systems in bacterial pathogens. This review article addresses the recent efforts to modulate these antimicrobial efflux transporters from a molecular perspective. Such investigations can potentially restore the clinical efficacy of infectious disease chemotherapy.