Alma María Mejía Fernández de Velasco
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Alma María Mejía Fernández de Velasco has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Ana Cornejo Gutiérrez
Health Center Barcelona. Móstoles. Ministry of Health of Community of Madrid, Madrid, Spain
1 shared publication - Encarnación Donoso Navarro
Clinical Analysis and Biochemistry Service, Puerta de Hierro University Hospital, Madrid, Spain
1 shared publication - Gloria Cabañas Pujadas
Cardiovascular Disease Surveillance Technical Unit, Directorate-General of Public Health. Ministry of Health of Community of Madrid, Madrid, Spain
1 shared publication - Honorato Ortiz-Marrón
Servicio de Epidemiología, Dirección General de Salud Pública, Consejería de Sanidad, Madrid, Spain
1 shared publication - Iñaki Galán
National Centre for Epidemiology, Instituto de Salud Carlos III (ISCIII), Madrid, Spain
1 shared publication - Mar Burreros García
Health Center Collado Mediano. Collado Mediano, Ministry of Health of Community of Madrid, Madrid, Spain
1 shared publication
Latest Publications
- Open Access
- 11 October 2023
- Published by Springer Nature in European Journal of Pediatrics
- Vol. 182 (12) , 5649-5659
Association between biomarkers of iron status and cardiometabolic risk in Spanish children aged 9–10 years. The ELOIN study
The relationship between iron metabolism and cardiometabolic risk factors has been scarcely studied in children, and the results are controversial. The objective of this study was to evaluate the association between iron parameters and lipid, glycemic and blood pressure alterations in the pediatric population. This was a cross-sectional study of 1954 children between 9 and 10 years of age in Madrid (Spain), participants in a longitudinal study of childhood obesity. Iron metabolism parameters, i.e., serum iron (Is), ferritin (Fs), transferrin (Tf) and transferrin saturation (STf) and lipid, glycemic and blood pressure profiles were evaluated. Odds ratios (ORs) were estimated using logistic regression models adjusted for sociodemographic characteristics, diet, physical activity, C-reactive protein and body mass index. Compared with the participants in the low Is and STf tertiles, those in the upper tertiles had a lower risk of low HDL-Chol (OR: 0.34; 95%CI: 0.17; 0.67) and OR: 0.44 (95%CI: 0.23; 0.84), respectively, and children in the upper Fs tertile had an OR of 2.07 (95%CI: 1.16; 3.68) for low HDL-Chol. Children in the highest Is and STf tertiles had a lower risk of prediabetes [OR: 0.63 (95%CI: 0.41; 0.97) and OR: 0.53 (95%CI: 0.34; 0.82)] and insulin resistance (IR) (OR: 0.37; 95%CI: 0.22; 0.64), and those in the upper Tf tertile had a higher risk of IR (OR: 1.90; 95%CI: 1.16; 3.12). An increased risk of hypertension was found only in children in the upper Fs tertile (OR: 1.46; 95%CI: 1.01; 2.13). Conclusions: Biomarkers of iron metabolism are associated with cardiometabolic alterations in the pediatric population, with a variable direction and magnitude depending on the indicators used. What is Known:• Iron metabolism is related to important cardiometabolic alterations such as metabolic syndrome and its components.• Association between biomarkers of iron status and cardiometabolic risk have been less explored in children. What is New:• Biomarkers of iron metabolism are associated with cardiometabolic alterations in the pediatric population.• Iron parameters in the pediatric population could be of great help to detect and prevent cardiometabolic abnormalities early.
- 11 October 2023
- Published by Springer Nature in European Journal of Pediatrics
- Vol. 182 (12) , 5649-5659
Open AccessAssociation between biomarkers of iron status and cardiometabolic risk in Spanish children aged 9–10 years. The ELOIN study
The relationship between iron metabolism and cardiometabolic risk factors has been scarcely studied in children, and the results are controversial. The objective of this study was to evaluate the association between iron parameters and lipid, glycemic and blood pressure alterations in the pediatric population. This was a cross-sectional study of 1954 children between 9 and 10 years of age in Madrid (Spain), participants in a longitudinal study of childhood obesity. Iron metabolism parameters, i.e., serum iron (Is), ferritin (Fs), transferrin (Tf) and transferrin saturation (STf) and lipid, glycemic and blood pressure profiles were evaluated. Odds ratios (ORs) were estimated using logistic regression models adjusted for sociodemographic characteristics, diet, physical activity, C-reactive protein and body mass index. Compared with the participants in the low Is and STf tertiles, those in the upper tertiles had a lower risk of low HDL-Chol (OR: 0.34; 95%CI: 0.17; 0.67) and OR: 0.44 (95%CI: 0.23; 0.84), respectively, and children in the upper Fs tertile had an OR of 2.07 (95%CI: 1.16; 3.68) for low HDL-Chol. Children in the highest Is and STf tertiles had a lower risk of prediabetes [OR: 0.63 (95%CI: 0.41; 0.97) and OR: 0.53 (95%CI: 0.34; 0.82)] and insulin resistance (IR) (OR: 0.37; 95%CI: 0.22; 0.64), and those in the upper Tf tertile had a higher risk of IR (OR: 1.90; 95%CI: 1.16; 3.12). An increased risk of hypertension was found only in children in the upper Fs tertile (OR: 1.46; 95%CI: 1.01; 2.13). Conclusions: Biomarkers of iron metabolism are associated with cardiometabolic alterations in the pediatric population, with a variable direction and magnitude depending on the indicators used. What is Known:• Iron metabolism is related to important cardiometabolic alterations such as metabolic syndrome and its components.• Association between biomarkers of iron status and cardiometabolic risk have been less explored in children. What is New:• Biomarkers of iron metabolism are associated with cardiometabolic alterations in the pediatric population.• Iron parameters in the pediatric population could be of great help to detect and prevent cardiometabolic abnormalities early.