Mohammed Hassan
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Mohammed Hassan has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Bradley E. Britigan
Department of Pathology, Microbiology and Immunology, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA
2 shared publications - Prabagaran Narayanasamy
Department of Internal Medicine, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA
2 shared publications - Seoung-Ryoung Choi
Department of Pathology, Microbiology and Immunology, College of Medicine, University of Nebraska Medical Center, Omaha, NE 68198, USA
2 shared publications - Wena Shafeeq Tawfeeq2 shared publications
- Ghafoor Ahmed Mam Rasul1 shared publication
- Hassan Hussein Hama Amin1 shared publication
Latest Publications
- Open Access
- 1 January 2025
- Published by Wiley in Applied and Environmental Soil Science
- Vol. 2025 (1)
Impact of Crop Residue Burning on Soil Properties, Microbial Activity, and CO 2 Emissions
Crop residue burning, a common agricultural practice in wheat cultivation, has significant implications for soil health, nutrient cycling, and microbial communities. This study evaluates the effects of residue burning on soil physicochemical properties, microbial populations, and CO 2 emissions in wheat fields across Wazha village and Sitak, Sulaymaniyah Province, Kurdistan, Iraq. Post‐burning analysis revealed a consistent shift in soil texture from silty clay loam to clay loam due to reduced silt content. Soil organic matter significantly declined from 15.63 ± 0.87 to 11.78 ± 0.28 g/kg ( p ≤ 0.05), alongside a marked decrease in magnesium concentration from 0.18 ± 0.02 to 0.06 ± 0.02 mmol/L ( p ≤ 0.05). In contrast, other parameters such as pH, electrical conductivity, calcium, potassium, and nitrogen remained largely unaffected. Microbial populations, including bacteria, fungi, and actinomycetes, exhibited resilience, showing no significant changes in abundance. CO 2 emissions demonstrated an initial rapid release of CO 2 ‐C due to microbial degradation of organic matter, followed by a slower mineralization rate over time. These findings highlight the detrimental impact of crop residue burning on essential soil properties, particularly organic matter and magnesium, which are critical for maintaining soil fertility. The study emphasizes the need for sustainable agricultural practices to mitigate the negative effects of residue burning, enhance soil health, and support long‐term agricultural productivity.
- 1 January 2025
- Published by Wiley in Applied and Environmental Soil Science
- Vol. 2025 (1)
Open AccessImpact of Crop Residue Burning on Soil Properties, Microbial Activity, and CO 2 Emissions
Crop residue burning, a common agricultural practice in wheat cultivation, has significant implications for soil health, nutrient cycling, and microbial communities. This study evaluates the effects of residue burning on soil physicochemical properties, microbial populations, and CO 2 emissions in wheat fields across Wazha village and Sitak, Sulaymaniyah Province, Kurdistan, Iraq. Post‐burning analysis revealed a consistent shift in soil texture from silty clay loam to clay loam due to reduced silt content. Soil organic matter significantly declined from 15.63 ± 0.87 to 11.78 ± 0.28 g/kg ( p ≤ 0.05), alongside a marked decrease in magnesium concentration from 0.18 ± 0.02 to 0.06 ± 0.02 mmol/L ( p ≤ 0.05). In contrast, other parameters such as pH, electrical conductivity, calcium, potassium, and nitrogen remained largely unaffected. Microbial populations, including bacteria, fungi, and actinomycetes, exhibited resilience, showing no significant changes in abundance. CO 2 emissions demonstrated an initial rapid release of CO 2 ‐C due to microbial degradation of organic matter, followed by a slower mineralization rate over time. These findings highlight the detrimental impact of crop residue burning on essential soil properties, particularly organic matter and magnesium, which are critical for maintaining soil fertility. The study emphasizes the need for sustainable agricultural practices to mitigate the negative effects of residue burning, enhance soil health, and support long‐term agricultural productivity.
- Open Access
- 22 August 2024
- Published by MDPI AG in Current Issues in Molecular Biology
- Vol. 46 (8) , 9149-9161
Antimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes
Metals play vital roles in biological systems, with iron/heme being essential for cellular and metabolic functions necessary for survival and/or virulence in many bacterial pathogens. Given the rise of bacterial resistance to current antibiotics, there is an urgent need for the development of non-toxic and novel antibiotics that do not contribute to resistance to other antibiotics. Gallium, which mimics iron, has emerged as a promising antimicrobial agent, offering a novel approach to combat bacterial infections. Gallium does not have any known functions in biological systems. Gallium exerts its effects primarily by replacing iron in redox enzymes, effectively inhibiting bacterial growth by targeting multiple iron/heme-dependent biological processes and suppressing the development of drug resistance. The aim of this review is to highlight recent findings on the mechanisms of action of gallium and provide further insights into the development of gallium-based compounds. Understanding the mechanisms underlying gallium’s biological activities is crucial for designing drugs that enhance their therapeutic therapies while minimizing side effects, offering promising avenues for the treatment of infectious diseases.
- 22 August 2024
- Published by MDPI AG in Current Issues in Molecular Biology
- Vol. 46 (8) , 9149-9161
Open AccessAntimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes
Metals play vital roles in biological systems, with iron/heme being essential for cellular and metabolic functions necessary for survival and/or virulence in many bacterial pathogens. Given the rise of bacterial resistance to current antibiotics, there is an urgent need for the development of non-toxic and novel antibiotics that do not contribute to resistance to other antibiotics. Gallium, which mimics iron, has emerged as a promising antimicrobial agent, offering a novel approach to combat bacterial infections. Gallium does not have any known functions in biological systems. Gallium exerts its effects primarily by replacing iron in redox enzymes, effectively inhibiting bacterial growth by targeting multiple iron/heme-dependent biological processes and suppressing the development of drug resistance. The aim of this review is to highlight recent findings on the mechanisms of action of gallium and provide further insights into the development of gallium-based compounds. Understanding the mechanisms underlying gallium’s biological activities is crucial for designing drugs that enhance their therapeutic therapies while minimizing side effects, offering promising avenues for the treatment of infectious diseases.
- Open Access
- 1 August 2024
- Published by MDPI AG in Preprints.org
Antimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes
Metals play vital roles in biological systems, with iron/heme being essential for cellular and metabolic functions necessary for survival and/or virulence in many bacterial pathogens. Given the rise of bacterial resistance to current antibiotics, there is an urgent need for the development of non-toxic and novel antibiotics that do not contribute to resistance to other antibiotics. Gallium, which mimics iron, has emerged as a promising antimicrobial agent, offering a novel approach to combat bacterial infections. Gallium does not have any known functions in biological systems. Gallium exerts its effects primarily by replacing iron in redox enzymes, effectively inhibiting bacterial growth by targeting multiple iron/heme-dependent biological processes and suppressing the development of drug resistance. The aim of this review is to highlight recent findings on the mechanisms of action of gallium and provide further insights into the development of gallium-based compounds. Understanding the mechanisms underlying gallium’s biological activities will enhance its therapeutic application across various medical fields, offering promising avenues for the treatment of infectious diseases, cancer, and inflammatory conditions.
- 1 August 2024
- Published by MDPI AG in Preprints.org
Open AccessAntimicrobial Activity of Gallium(III) Compounds: Pathogen-Dependent Targeting of Multiple Iron/Heme-Dependent Biological Processes
Metals play vital roles in biological systems, with iron/heme being essential for cellular and metabolic functions necessary for survival and/or virulence in many bacterial pathogens. Given the rise of bacterial resistance to current antibiotics, there is an urgent need for the development of non-toxic and novel antibiotics that do not contribute to resistance to other antibiotics. Gallium, which mimics iron, has emerged as a promising antimicrobial agent, offering a novel approach to combat bacterial infections. Gallium does not have any known functions in biological systems. Gallium exerts its effects primarily by replacing iron in redox enzymes, effectively inhibiting bacterial growth by targeting multiple iron/heme-dependent biological processes and suppressing the development of drug resistance. The aim of this review is to highlight recent findings on the mechanisms of action of gallium and provide further insights into the development of gallium-based compounds. Understanding the mechanisms underlying gallium’s biological activities will enhance its therapeutic application across various medical fields, offering promising avenues for the treatment of infectious diseases, cancer, and inflammatory conditions.
- 23 November 2023
- Published by Elsevier in Bioresource Technology Reports
- Vol. 25
Bioremediation of heavy metals in contaminated environments using Comamonas species: A narrative review
- 23 November 2023
- Published by Elsevier in Bioresource Technology Reports
- Vol. 25
Bioremediation of heavy metals in contaminated environments using Comamonas species: A narrative review