Juan Rojas
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Juan Rojas has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Cristina Puig-Ram
Institut de Recerca Sant Joan de Déu
1 shared publication - David Hervás
Department of Applied Statistics and Operational Research and Quality, Universitat Politècnica de València, València, Spain
1 shared publication - Eugenia Ibáñez Albert
Department of Physical Medicine & Rehabilitation, Hospital Universitario y Politécnico la Fe, 46026 Valencia, Spain
1 shared publication - Inmaculada Pitarch-Castellano
Department of Pediatrics, Hospital Universitario y Politécnico la Fe, 46026 Valencia, Spain
1 shared publication - Marcos Madruga-Garrido
Hospital Viamed Santa Angela de la Cruz, Sevilla and Neurolinkia, 41018 Seville, Spain
1 shared publication - Maria Grazia Cattinari
Fundación Atrofia Muscular Espinal España (FundAME), Madrid, Spain
1 shared publication
Latest Publications
- Open Access
Pain in Children and Adolescents with Spinal Muscular Atrophy: A Longitudinal Study from a Patient Registry
Spinal muscular atrophy (SMA) is a devastating genetic neurodegenerative disease caused by the insufficient production of Survival Motor Neuron (SMN) protein. It presents different phenotypes with frequent contractures and dislocations, scoliosis, and pain. This study aims to report the prevalence and description of pain and how it affects daily life by analyzing a new ad hoc questionnaire. An observational study of patients under 18 years of age with SMA was conducted at two referral centers in Spain. Data were analyzed using a descriptive analysis and a Bayesian ordinal regression model to assess the association with clinical and demographic variables. Fifty-one individuals were included in this study, 43% of whom reported pain with a median duration of 5.2 years and a mean Visual Analogic Scale (VAS) score of 5. Notably, 77% were receiving disease-modifying treatment, with more than 50% receiving analgesic treatment. The Bayesian model showed that functional status, lower limb contractures, and number of visits have a high probability (>90%) of influencing pain. Thus, the prevalence of pain in the SMA population under 18 years is substantial, and its presence could be associated with lower limb contractures, better functional status, and higher RULM (Revised Upper Limb Module) scores.
Open AccessPain in Children and Adolescents with Spinal Muscular Atrophy: A Longitudinal Study from a Patient Registry
Spinal muscular atrophy (SMA) is a devastating genetic neurodegenerative disease caused by the insufficient production of Survival Motor Neuron (SMN) protein. It presents different phenotypes with frequent contractures and dislocations, scoliosis, and pain. This study aims to report the prevalence and description of pain and how it affects daily life by analyzing a new ad hoc questionnaire. An observational study of patients under 18 years of age with SMA was conducted at two referral centers in Spain. Data were analyzed using a descriptive analysis and a Bayesian ordinal regression model to assess the association with clinical and demographic variables. Fifty-one individuals were included in this study, 43% of whom reported pain with a median duration of 5.2 years and a mean Visual Analogic Scale (VAS) score of 5. Notably, 77% were receiving disease-modifying treatment, with more than 50% receiving analgesic treatment. The Bayesian model showed that functional status, lower limb contractures, and number of visits have a high probability (>90%) of influencing pain. Thus, the prevalence of pain in the SMA population under 18 years is substantial, and its presence could be associated with lower limb contractures, better functional status, and higher RULM (Revised Upper Limb Module) scores.