Feidan Yu
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Feidan Yu has a total of 16 co-authors. Here are the top co-authors by number of shared publications:
- Cailing Pu
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3# East Qingchun Road, Hangzhou 310016, China
1 shared publication - Chao Ren
Key Laboratory of Quantum Precision Measurement of Zhejiang Province, School of Physics and Optical Engineering, Zhejiang University of Technology, Hangzhou 310023, China
1 shared publication - Dongzi Zhang
Key Laboratory of Quantum Precision Measurement of Zhejiang Province, School of Physics and Optical Engineering, Zhejiang University of Technology, Hangzhou 310023, China
1 shared publication - Fuyan Wang
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 3# East Qingchun Road, Hangzhou 310016, China
1 shared publication - Hongjie Hu
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China
1 shared publication - Junhao Zheng
Key Laboratory of Multi-Omics Precision Diagnosis and Treatment of Liver Diseases, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China
1 shared publication
Latest Publications
- Open Access
- 7 November 2026
- Published by MDPI AG in Biosensors
- Vol. 16 (11) , 639
Magnetic Relaxation Measurements of Ex Vivo Human Liver Specimens Using a SERF Magnetometer
Reliable assessment of liver iron concentration (LIC) is important for diagnosing and monitoring iron overload disorders. We used a spin exchange relaxation free (SERF) atomic magnetometer to record magnetic relaxation signals from resected human liver tissue. A total of 23 specimens from 20 patients, including normal, fatty, cirrhotic, and hepatocellular carcinoma (HCC) liver, were polarized with a Helmholtz coil inside a magnetic shield, and the field decay after switch off was recorded. For each specimen, a water-referenced, mass-normalized relaxation amplitude ΔB (pT/g) was derived. ΔB was compared with the HISTO-derived water transverse relaxation rates, , from the patients’ clinical MRI. For HCC, SERF measurements were made on resected tumor tissue, whereas MRI sampled non-cancerous liver parenchyma in the same patient. Within each category, ΔB increased with and rank order agreed fully in three of the four categories. Slope differences between categories were significant with conventional standard errors but not with heteroscedasticity-consistent (HC3) standard errors and are therefore regarded as exploratory. These measurements establish a SERF workflow for comparing post-polarization magnetic relaxation amplitudes across resected human liver specimens.- 7 November 2026
- Published by MDPI AG in Biosensors
- Vol. 16 (11) , 639
Open AccessMagnetic Relaxation Measurements of Ex Vivo Human Liver Specimens Using a SERF Magnetometer
Reliable assessment of liver iron concentration (LIC) is important for diagnosing and monitoring iron overload disorders. We used a spin exchange relaxation free (SERF) atomic magnetometer to record magnetic relaxation signals from resected human liver tissue. A total of 23 specimens from 20 patients, including normal, fatty, cirrhotic, and hepatocellular carcinoma (HCC) liver, were polarized with a Helmholtz coil inside a magnetic shield, and the field decay after switch off was recorded. For each specimen, a water-referenced, mass-normalized relaxation amplitude ΔB (pT/g) was derived. ΔB was compared with the HISTO-derived water transverse relaxation rates, , from the patients’ clinical MRI. For HCC, SERF measurements were made on resected tumor tissue, whereas MRI sampled non-cancerous liver parenchyma in the same patient. Within each category, ΔB increased with and rank order agreed fully in three of the four categories. Slope differences between categories were significant with conventional standard errors but not with heteroscedasticity-consistent (HC3) standard errors and are therefore regarded as exploratory. These measurements establish a SERF workflow for comparing post-polarization magnetic relaxation amplitudes across resected human liver specimens. - Open Access
- 28 January 2024
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 13 (3) , 753
Optimizing Clinical Cardiac MRI Workflow through Single Breath-Hold Compressed Sensing Cine: An Evaluation of Feasibility and Efficiency
Background: Although compressed sensing (CS) accelerated cine holds immense potential to replace conventional cardiovascular magnetic resonance (CMR) cine, how to use CS-based cine appropriately during clinical CMR examinations still needs exploring. Methods: A total of 104 patients (46.5 ± 17.1 years) participated in this prospective study. For each participant, a balanced steady state free precession (bSSFP) cine was acquired as a reference, followed by two CS accelerated cine sequences with identical parameters before and after contrast injection. Lastly, a CS accelerated cine sequence with an increased flip angle was obtained. We subsequently compared scanning time, image quality, and biventricular function parameters between these sequences. Results: All CS cine sequences demonstrated significantly shorter acquisition times compared to bSSFPref cine (p < 0.001). The bSSFPref cine showed higher left ventricular ejection fraction (LVEF) than all CS cine sequences (all p < 0.001), but no significant differences in LVEF were observed among the three CS cine sequences. Additionally, CS cine sequences displayed superior global image quality (p < 0.05) and fewer artifacts than bSSFPref cine (p < 0.005). Unenhanced CS cine and enhanced CS cine with increased flip angle showed higher global image quality than other cine sequences (p < 0.005). Conclusion: Single breath-hold CS cine delivers precise biventricular function parameters and offers a range of benefits including shorter scan time, better global image quality, and diminished motion artifacts. This innovative approach holds great promise in replacing conventional bSSFP cine and optimizing the CMR examination workflow.
- 28 January 2024
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 13 (3) , 753
Open AccessOptimizing Clinical Cardiac MRI Workflow through Single Breath-Hold Compressed Sensing Cine: An Evaluation of Feasibility and Efficiency
Background: Although compressed sensing (CS) accelerated cine holds immense potential to replace conventional cardiovascular magnetic resonance (CMR) cine, how to use CS-based cine appropriately during clinical CMR examinations still needs exploring. Methods: A total of 104 patients (46.5 ± 17.1 years) participated in this prospective study. For each participant, a balanced steady state free precession (bSSFP) cine was acquired as a reference, followed by two CS accelerated cine sequences with identical parameters before and after contrast injection. Lastly, a CS accelerated cine sequence with an increased flip angle was obtained. We subsequently compared scanning time, image quality, and biventricular function parameters between these sequences. Results: All CS cine sequences demonstrated significantly shorter acquisition times compared to bSSFPref cine (p < 0.001). The bSSFPref cine showed higher left ventricular ejection fraction (LVEF) than all CS cine sequences (all p < 0.001), but no significant differences in LVEF were observed among the three CS cine sequences. Additionally, CS cine sequences displayed superior global image quality (p < 0.05) and fewer artifacts than bSSFPref cine (p < 0.005). Unenhanced CS cine and enhanced CS cine with increased flip angle showed higher global image quality than other cine sequences (p < 0.005). Conclusion: Single breath-hold CS cine delivers precise biventricular function parameters and offers a range of benefits including shorter scan time, better global image quality, and diminished motion artifacts. This innovative approach holds great promise in replacing conventional bSSFP cine and optimizing the CMR examination workflow.