Woo Jin Lee
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Research Subjects
Woo Jin Lee has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Jae-Chul Jung
Life Science Research Institute, NOVAREX Co., Ltd., Cheongju 28220, Chungbuk, Republic of Korea
3 shared publications - Kyungmi Kim
Life Science Research Institute, NOVAREX Co., Ltd., Cheongju, Korea
2 shared publications - Seong-Min Kim
Department of Foods and Nutrition, Kookmin University, Seoul 02707, Korea
2 shared publications - Singeun Kim
R&D Center, NOVAREX. Co., Ltd., Cheongju, Korea
2 shared publications - Ha-Jin Kim
Department of Foods & Nutrition, Kookmin University, 77 Jeongneung-ro, Seongbuk-gu, Seoul 02707, Republic of Korea
1 shared publication - Jee-Young Imm
Department of Foods and Nutrition, Kookmin University, Seoul, Korea
1 shared publication
Latest Publications
- Open Access
- 19 May 2024
- Published by MDPI AG in Applied Sciences
- Vol. 14 (10) , 4301
Alleviating Effect of a Flower Extract of Styphnolobium japonicum L. on Symptoms of Experimentally Induced Osteoarthritis in Rats
In the present study, we prepared an ethanol extract from the flowers of Styphnolobium japonicum L. (SJFE) and found that it contains rutin as a major constituent as well as quercetin kaempferol and isorhamnetin as minor components. In lipopolysaccharide-stimulated RAW 264.7 macrophages, we observed that SJFE significantly inhibited the production of nitric oxide and the expression of major inflammatory biomarkers such as inducible NO synthase, cyclooxygenase-2, interleukin (IL)-6, and IL-1β significantly. Based on these in vitro results, we investigated the anti-inflammatory properties of SJFE on osteoarthritis (OA) of the left hind knee joints induced by monosodium iodoacetate in rats. SJFE was orally administered to the rats with arthritis for 4 weeks, and the following results were obtained. The rats treated with SJFE exhibited a 24% improvement in the weight-bearing index of their affected legs, as well as reductions of 31.5% and 23.2% in serum levels of cartilage oligomeric matrix protein and C-terminal telopeptide 2, respectively. Additionally, Mankin’s score, an indicator used to assess the severity of joint cartilage damage, decreased by 2.75 points compared to the control with no treatment. These findings suggest that SJFE possesses anti-inflammatory properties and can alleviate symptoms of OA, indicating its potential to offer relief to individuals suffering from arthritis.
- 19 May 2024
- Published by MDPI AG in Applied Sciences
- Vol. 14 (10) , 4301
Open AccessAlleviating Effect of a Flower Extract of Styphnolobium japonicum L. on Symptoms of Experimentally Induced Osteoarthritis in Rats
In the present study, we prepared an ethanol extract from the flowers of Styphnolobium japonicum L. (SJFE) and found that it contains rutin as a major constituent as well as quercetin kaempferol and isorhamnetin as minor components. In lipopolysaccharide-stimulated RAW 264.7 macrophages, we observed that SJFE significantly inhibited the production of nitric oxide and the expression of major inflammatory biomarkers such as inducible NO synthase, cyclooxygenase-2, interleukin (IL)-6, and IL-1β significantly. Based on these in vitro results, we investigated the anti-inflammatory properties of SJFE on osteoarthritis (OA) of the left hind knee joints induced by monosodium iodoacetate in rats. SJFE was orally administered to the rats with arthritis for 4 weeks, and the following results were obtained. The rats treated with SJFE exhibited a 24% improvement in the weight-bearing index of their affected legs, as well as reductions of 31.5% and 23.2% in serum levels of cartilage oligomeric matrix protein and C-terminal telopeptide 2, respectively. Additionally, Mankin’s score, an indicator used to assess the severity of joint cartilage damage, decreased by 2.75 points compared to the control with no treatment. These findings suggest that SJFE possesses anti-inflammatory properties and can alleviate symptoms of OA, indicating its potential to offer relief to individuals suffering from arthritis.
- Open Access
- 1 January 2023
- Published by XMLink in Food Supplements and Biomaterials for Health
- Vol. 3 (4)
Alleviating Effect of the Salt-Out Extract of Styphnolobium japonicum Fruit on Photo-Aging in the Skin of Hairless Mice
Kim SM, et al. Food Suppl Biomater Health. 2023 Dec;3(4):e25. https://doi.org/10.52361/fsbh.2023.3.e25
- 1 January 2023
- Published by XMLink in Food Supplements and Biomaterials for Health
- Vol. 3 (4)
Open AccessAlleviating Effect of the Salt-Out Extract of Styphnolobium japonicum Fruit on Photo-Aging in the Skin of Hairless Mice
Kim SM, et al. Food Suppl Biomater Health. 2023 Dec;3(4):e25. https://doi.org/10.52361/fsbh.2023.3.e25
- Open Access
- 1 January 2023
- Published by XMLink in Food Supplements and Biomaterials for Health
- Vol. 3 (4)
Effect of the Extract of Styphnolobium japonicum Fruit on the Secretion of Tissue-Damaging Mediators From Macrophages and Keratinocytes Following Exposure to External Triggers
Kim SM, et al. Food Suppl Biomater Health. 2024 Dec;3(4):e28. https://doi.org/10.52361/fsbh.2023.3.e28
- 1 January 2023
- Published by XMLink in Food Supplements and Biomaterials for Health
- Vol. 3 (4)
Open AccessEffect of the Extract of Styphnolobium japonicum Fruit on the Secretion of Tissue-Damaging Mediators From Macrophages and Keratinocytes Following Exposure to External Triggers
Kim SM, et al. Food Suppl Biomater Health. 2024 Dec;3(4):e28. https://doi.org/10.52361/fsbh.2023.3.e28
- 1 July 2017
- Published by Institute of Electrical and Electronics Engineers (IEEE)
- Vol. 46, 278-283
An automated testing method for AUTOSAR software components based on SiL simulation
Testing automotive software using Software-in-the-Loop (SiL) simulation doesn't require the hardware such as test vehicles and ECUs. Existing testing techniques based on SiL rely on manual processes because automation techniques of testing AUTOSAR components using SiL simulation have not yet been established. In this paper, we present an automated testing technique and its implementation based on SiL simulation. We have evaluated the effectiveness and efficiency of the presented technique through a case study.
- 1 July 2017
- Published by Institute of Electrical and Electronics Engineers (IEEE)
- Vol. 46, 278-283
An automated testing method for AUTOSAR software components based on SiL simulation
Testing automotive software using Software-in-the-Loop (SiL) simulation doesn't require the hardware such as test vehicles and ECUs. Existing testing techniques based on SiL rely on manual processes because automation techniques of testing AUTOSAR components using SiL simulation have not yet been established. In this paper, we present an automated testing technique and its implementation based on SiL simulation. We have evaluated the effectiveness and efficiency of the presented technique through a case study.