Jasmin Preiß

In humans, the first year of life is characterized by rapid developmental changes, including substantial brain maturation. As a result, neural responses to auditory stimuli undergo marked changes during this period. In this study, we followed 69 infants across their first year of life and recorded high-density electroencephalography (hdEEG) at 2 weeks, 6 months, and 12 months postpartum. Infants were presented with pure beep tones to examine the development of neural responses to auditory stimulation. We analysed event-related potentials (ERPs), inter-trial phase coherence (ITPC), and time-frequency (TF) responses to the beep tones and controlled for arousal state during stimulus presentation. We found that with increasing age, neural responses became more pronounced and showed reduced trial-to-trial variability. Phase synchronization increased from 2 weeks to later developmental stages in a broad low-frequency range (0 to 11 Hz), indicating improved temporal alignment of brain responses over time. However, phase synchronization decreased from 6 to 12 months, suggesting a developmental transition towards more differentiated brain activity. Taken together, these findings demonstrate that auditory maturation during the first year of life follows a non-linear trajectory driven by dynamic changes in neural synchronization, reflecting the progressive refinement of functional neural circuits. Our results thus provide a critical benchmark for understanding the neural dynamics underlying sensory development during this period.

Objective: Sex hormones testosterone and estradiol have been related to children’s language development. Expanding the focus on dehydroepiandrosterone (DHEA), which has not yet been considered as a biological marker of language ability, may provide novel insights, as emerging evidence suggests that fetal DHEA plays a critical role in the organization of the neonatal brain, potentially shaping later language development. The present study investigated whether fetal DHEA, compared to fetal testosterone, is associated with infant language development. Design and methods: DHEA and testosterone concentrations were measured in newborn hair strands ( n = 63) collected two weeks after birth, capturing fetal long-term hormone secretions during the third trimester of pregnancy. At six months of age, children’s language abilities were assessed using the German version of the Bayley Scales of Infant Development. Results. Linear regression analysis revealed fetal DHEA levels to be significantly associated with language abilities at six months of age, with lower DHEA levels corresponding to higher language scores. Control analyses assessing general cognitive abilities showed no association of fetal DHEA levels with infant cognitive function. Testosterone levels were not associated with language. Conclusions: The current study identifies fetal DHEA levels extracted from newborn hair samples as a potential biological factor influencing infant language development.

Early mother-infant interaction is believed to have a significant impact on the social, cognitive, and emotional development of children. These interactions are not only influenced by child and contextual factors but also by the mother’s personality traits and strain. In this study, we investigated the relation between maternal factors such as personality, depressive symptoms, or experiencing of emotions, and (i) children’s early cognitive development and (ii) interaction patterns in a sample of 116 mother-child dyads (mean child age = 18.63 months ± 6.42). Maternal factors were assessed using standardized questionnaires and toddlers’ cognitive development was measured using the Bayley Scales of Infant and Toddler Development. Interaction patterns were evaluated using the CARE-Index. The study found that children of mothers who scored higher in agreeableness, a personality trait reflecting compassion and cooperation, performed better in cognitive assessments. Additionally, mothers who placed significant importance on their bodily signals to assess their overall well-being had higher scores in the quality of interaction with their child. Statistical trends suggested that mothers with higher levels of conscientiousness, indicative of being organized and responsible, tended to be more responsive in the interaction with their infants, while those with higher levels of neuroticism, characterized by a tendency towards negative emotions, were more likely to have toddlers who inhibit their true negative affect. Finally, there was a trend indicating that maternal depression was associated with increased maternal controlling behavior towards toddlers. Overall, these findings show the intricate relation between maternal behavior and state with dyadic interaction quality. This should underline that optimal infant development is only possible if mothers are well supported especially if in need due to various burdens such as depressive symptoms.

The quality of early interactions between parents and their children is essential for fostering healthy development. This study investigates the relationship between parent-infant interaction, language development and infant regulation, as well as the distinct roles of mothers and fathers.A total of 40 mother-child dyads were examined at six months postpartum. Self-report questionnaires were used to evaluate maternal depressive symptoms (Edinburgh Postnatal Depression Scale), parental attachment-related attitudes (Revised Adult Attachment Scale), and infant regulation (Questionnaire for Crying, Feeding and Sleeping). Mother-infant interactions were recorded on video and subsequently evaluated using the Infant CARE-Index, with an additional assessment of father-infant interaction in a smaller subsample of 20 dyads.The findings indicate that higher maternal depressive symptoms were linked to an increased prevalence of infant regulatory challenges, such as crying and sleep difficulties. Notably, fathers demonstrated significantly higher interaction quality than mothers, despite similar co-regulatory behaviors between parents. These results underscore the impact of maternal mental health on infant regulation and emphasize the importance of father involvement in early child development.

Early mother-infant interaction is believed to have a significant impact on the social, cognitive, and emotional development of children. These interactions are not only influenced by child and contextual factors but also by the mother’s personality traits and strain. In this study, we investigated the relation between maternal factors such as personality, depressive symptoms, or experiencing of emotions, with (i) children’s early cognitive development and (ii) interaction patterns in a sample of 116 mother-child dyads (mean child age = 18.63 months ± 6.42). Maternal factors were assessed using standardized questionnaires, children’s cognitive development was measured using the Bayley Scales of Infant and Toddler Development, and interaction patterns were evaluated using the CARE-Index. The study found that children of mothers who scored higher in agreeableness performed better in cognitive assessments. Additionally, our analysis revealed statistical trends indicating that mothers with higher levels of conscientiousness tended to be less unresponsive in the interaction with their infants, while those with higher levels of neuroticism were more likely to exhibit compulsive behavior in their toddlers. Additionally, there was a trend indicating that maternal depression was associated with increased maternal controlling behavior towards toddlers. Finally, mothers who placed significant importance on their bodily signals to assess their overall well-being had higher scores in the quality of interaction with their child. Overall, these findings show the intricate relation between maternal behavior and state with dyadic interaction quality. This should underline that optimal infant development is only possible if mothers are well supported especially if in need due to various burdens such as depressive symptoms.

Introduction Postpartum suicidal ideation is a significant concern, as it poses a risk for future suicide attempts, particularly in high income countries, where suicide ranks among the leading causes of death for postpartum mothers. The literature indicates a global average prevalence of postpartum suicidal ideation of approximately 7%, but for Austria and Germany there are few studies on this subject. Methods In a web-based survey for Austrian and German mothers of children born during the COVID-19 pandemic, several measures of mental health (depression, stress), social support and other parenting and pandemic-related questions were assessed in 1964 mothers. Based on the answers for the last item of the Edinburgh Postpartum Depression Scale, the suicidality risk and the presence or absence of suicidal ideation were computed. Furthermore, possible risk or protective factors for suicidality were investigated. Results The prevalence of suicidal ideation was 7.3%, which is in the range of the global prevalence reported in the literature, but two times higher than previous reports on German mothers. The three strongest risk factors for suicidal ideation were (i) high levels of stress (increased risk by 350%), (ii) a lack of perceived social support (increased risk by 265%), and (iii) a perceived negative effect of the pandemic on the relationship with the partner (increased risk by 223%). Not receiving help from family and friends, having a lower income, and feeling negatively impacted by the pandemic also significantly increased the risk of suicidal ideation. Discussion and conclusion The results indicate a higher prevalence of suicidality than previously reported in German mothers, and confirm the risk factors previously associated with depression and suicidality. These risk and protective factors could be targets of social and public health policies, while the first step should be a general screening program for suicidality in this population group.

Background: Becoming parents can be a big challenge, but how is this experience affected by the COVID-19 pandemic and its measures? Methods: Between 18.05.2021 and 01.07.2021, we conducted an online-survey to gain insight into becoming parents during the COVID-19 pandemic in Germany and Austria. The sample mentioned in this report consists of biological mothers living in Austria (n = 952) and Germany (n = 1012) who gave birth between the 16th of March 2020 (the beginning of the first lockdown in Austria) and the time of completion of the study. The mothers’ current stress levels were assessed with the Perceived Stress Scale (PSS), and postnatal depression symptoms were quantified with the Edinburgh Postnatal Depression Scale (EPDS). Furthermore, we included questions to measure perceived social support and pandemic-related stress. Results: Current stress levels (U = 555677.50, z = 5.90, p < .001) and postnatal depression symptoms (U = 546354.00, z = 5.15, p < .001) were significantly higher in the German sample as compared to the Austrian sample. Yet, Austrian mothers reported higher social support as compared to the German mothers (U = 387834.00, z = -7.48, p < .001). Furthermore, we found higher levels of perceived social support to be associated with lower current stress levels (rs = -.40, p < .001). On average, perceived stress was moderately high in both samples (MGermany = 18.58, SDGermany = 6.60; MAustria = 16.76, SDAustria = 6.57). Conclusions: Stress levels and depression symptoms seem to be high and prevalent due to the pandemic and it is highly indicated to take action such as supporting families in need and emphasising social support in order to reduce mental health problems of parents as well as their children in the aftermath of the pandemic. Key messages: • Findings underpin the protective role of social support against psychological distress in new parents and show the high strain at current. • Action needs to be taken in order to support parents and children at risk.