Giovanni Spagna
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Previous Organizations / Institutes
The organizations / institutes from the scholar's other articles in the past ten years
Giovanni Spagna has a total of 27 co-authors. Here are the top co-authors by number of shared publications:
- Anita Ierna
Institute of BioEconomy, National Research Council (CNR-IBE), Via P. Gaifami 18, 95126 Catania, Italy
2 shared publications - Giovanni Mauromicale
Department of Agriculture, Food and Environment (Di3A), University of Catania, Catania, Italy
2 shared publications - Laurent Audigé
Surgical Outcome Research Center, University Hospital Basel, Basel, Switzerland
2 shared publications Markus Scheibel
Department of Shoulder and Elbow Surgery, Schulthess Clinic, Zurich, Switzerland
2 shared publicationsPhilipp Moroder
Department of Shoulder and Elbow Surgery, Schulthess Clinic, Zurich, Switzerland
2 shared publications- Riccardo Nunzio Barbagallo
Dipartimento di Orticoltura, Floricoltura, Arboricoltura e Tecnologie Alimentari (DOFATA), University of Catania, Catania, Italy
2 shared publications
Latest Publications
- Open Access
- 11 August 2025
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 14 (16) , 5679
Lateralized Reverse Shoulder Arthroplasty vs. Medialized Design with Latissimus Dorsi Transfer for Cuff Tear Arthropathy with Loss of External Rotation and ER Lag Sign
Background: The management of irreparable posterosuperior rotator cuff tears with an isolated loss of external rotation presents significant challenges. Latissimus dorsi tendon transfer in conjunction with medialized reverse total shoulder arthroplasty has been employed to rectify external rotation deficits; however, lateralized RTSA designs may yield similar outcomes with a reduced incidence of complications. The objective of this study was to compare the clinical outcomes of lateralized reverse total shoulder arthroplasty without latissimus dorsi tendon transfer against medialized RTSA with LDT in patients with ILER and a positive external rotation lag sign. Methods: This retrospective cohort study involved 34 patients diagnosed with CTA and severe external rotation deficiency, characterized by a positive ER lag sign and 0° active ER. The patients were treated with either lateralized reverse total shoulder arthroplasty (n = 21) or medialized RTSA with LDT (n = 13). Outcomes evaluated preoperatively and at the 24-month follow-up comprised range of motion, ER lag sign, Constant–Murley Score, SPADI, and radiographic offset parameters. Statistical analyses were adjusted for age, sex, and baseline values. Results: At follow-up, 70% of patients undergoing lateralized RTSA exhibited resolution of ER lag, compared to 23% in the LDT group (p < 0.05). Active external rotation improvement was more significant in the LDT group (34.6° compared to 18.5°, p < 0.05). However, both groups exhibited comparable final external rotation and functional scores (CMS: 63 ± 9 vs. 63 ± 16; SPADI: 73 ± 20 vs. 74 ± 22). Lateralized RTSA demonstrated superior preservation of internal rotation, as evidenced by a higher percentage of patients achieving a negative Apley scratch test (67% compared to 23%, p < 0.05). A greater glenoidal offset correlated with improved postoperative external rotation and resolution of external rotation lag. The influence of teres minor integrity was more significant in the LDT group. Conclusions: Lateralized reverse total shoulder arthroplasty without latissimus dorsi tendon transfer provides similar functional restoration of external rotation in irreparable posterosuperior rotator cuff tear patients, accompanied by reduced complications, shorter surgical durations, and improved preservation of internal rotation. LDT has the potential to provide enhanced ER gains from a low baseline; however, it is characterized by increased invasiveness and technical complexity. Prosthetic lateralization is a biomechanically effective method for restoring external rotation in patients with rotator cuff arthropathy and external rotation deficits.
- 11 August 2025
- Published by MDPI AG in Journal of Clinical Medicine
- Vol. 14 (16) , 5679
Open AccessLateralized Reverse Shoulder Arthroplasty vs. Medialized Design with Latissimus Dorsi Transfer for Cuff Tear Arthropathy with Loss of External Rotation and ER Lag Sign
Background: The management of irreparable posterosuperior rotator cuff tears with an isolated loss of external rotation presents significant challenges. Latissimus dorsi tendon transfer in conjunction with medialized reverse total shoulder arthroplasty has been employed to rectify external rotation deficits; however, lateralized RTSA designs may yield similar outcomes with a reduced incidence of complications. The objective of this study was to compare the clinical outcomes of lateralized reverse total shoulder arthroplasty without latissimus dorsi tendon transfer against medialized RTSA with LDT in patients with ILER and a positive external rotation lag sign. Methods: This retrospective cohort study involved 34 patients diagnosed with CTA and severe external rotation deficiency, characterized by a positive ER lag sign and 0° active ER. The patients were treated with either lateralized reverse total shoulder arthroplasty (n = 21) or medialized RTSA with LDT (n = 13). Outcomes evaluated preoperatively and at the 24-month follow-up comprised range of motion, ER lag sign, Constant–Murley Score, SPADI, and radiographic offset parameters. Statistical analyses were adjusted for age, sex, and baseline values. Results: At follow-up, 70% of patients undergoing lateralized RTSA exhibited resolution of ER lag, compared to 23% in the LDT group (p < 0.05). Active external rotation improvement was more significant in the LDT group (34.6° compared to 18.5°, p < 0.05). However, both groups exhibited comparable final external rotation and functional scores (CMS: 63 ± 9 vs. 63 ± 16; SPADI: 73 ± 20 vs. 74 ± 22). Lateralized RTSA demonstrated superior preservation of internal rotation, as evidenced by a higher percentage of patients achieving a negative Apley scratch test (67% compared to 23%, p < 0.05). A greater glenoidal offset correlated with improved postoperative external rotation and resolution of external rotation lag. The influence of teres minor integrity was more significant in the LDT group. Conclusions: Lateralized reverse total shoulder arthroplasty without latissimus dorsi tendon transfer provides similar functional restoration of external rotation in irreparable posterosuperior rotator cuff tear patients, accompanied by reduced complications, shorter surgical durations, and improved preservation of internal rotation. LDT has the potential to provide enhanced ER gains from a low baseline; however, it is characterized by increased invasiveness and technical complexity. Prosthetic lateralization is a biomechanically effective method for restoring external rotation in patients with rotator cuff arthropathy and external rotation deficits.
- Open Access
- 3 July 2025
- Published by Elsevier in JSES Reviews, Reports, and Techniques
- Vol. 5 (4) , 1154-1158
Benefits and limitations of diagnostic shoulder arthroscopy for painful anatomical shoulder arthroplasty investigation
- 3 July 2025
- Published by Elsevier in JSES Reviews, Reports, and Techniques
- Vol. 5 (4) , 1154-1158
Open AccessBenefits and limitations of diagnostic shoulder arthroscopy for painful anatomical shoulder arthroplasty investigation
- 25 March 2024
- Published by Elsevier in Journal of Shoulder and Elbow Surgery
- Vol. 33 (10) , 2159-2170
Scapulothoracic orientation has a significant influence on the clinical outcome after reverse total shoulder arthroplasty
- 25 March 2024
- Published by Elsevier in Journal of Shoulder and Elbow Surgery
- Vol. 33 (10) , 2159-2170
Scapulothoracic orientation has a significant influence on the clinical outcome after reverse total shoulder arthroplasty
- 1 April 2013
- Published by International Society for Horticultural Science (ISHS) in Acta Horticulturae
- No. 983,p. 337-343
EFFECTS OF LOCATION AND GENOTYPE ON SOME QUALITY CHARACTERISTICS OF HEADS IN GLOBE ARTICHOKE DURING HARVEST TIME
ISHS VIII International Symposium on Artichoke, Cardoon and their Wild Relatives EFFECTS OF LOCATION AND GENOTYPE ON SOME QUALITY CHARACTERISTICS OF HEADS IN GLOBE ARTICHOKE DURING HARVEST TIME
- 1 April 2013
- Published by International Society for Horticultural Science (ISHS) in Acta Horticulturae
- No. 983,p. 337-343
EFFECTS OF LOCATION AND GENOTYPE ON SOME QUALITY CHARACTERISTICS OF HEADS IN GLOBE ARTICHOKE DURING HARVEST TIME
ISHS VIII International Symposium on Artichoke, Cardoon and their Wild Relatives EFFECTS OF LOCATION AND GENOTYPE ON SOME QUALITY CHARACTERISTICS OF HEADS IN GLOBE ARTICHOKE DURING HARVEST TIME
- 1 January 2007
- Published by International Society for Horticultural Science (ISHS) in Acta Horticulturae
- No. 730,p. 195-199
CASEINOLYTIC ACTIVITY EXPRESSION IN FLOWERS OF CYNARA CARDUNCULUS L.
ISHS VI International Symposium on Artichoke, Cardoon and Their Wild Relatives CASEINOLYTIC ACTIVITY EXPRESSION IN FLOWERS OF CYNARA CARDUNCULUS L.
- 1 January 2007
- Published by International Society for Horticultural Science (ISHS) in Acta Horticulturae
- No. 730,p. 195-199
CASEINOLYTIC ACTIVITY EXPRESSION IN FLOWERS OF CYNARA CARDUNCULUS L.
ISHS VI International Symposium on Artichoke, Cardoon and Their Wild Relatives CASEINOLYTIC ACTIVITY EXPRESSION IN FLOWERS OF CYNARA CARDUNCULUS L.
- 1 December 2000
- Published by Elsevier in Journal of Molecular Catalysis B: Enzymatic
- Vol. 11 (2-3) , 63-69
Stabilization of a β-glucosidase from Aspergillus niger by binding to an amine agarose gel
- 1 December 2000
- Published by Elsevier in Journal of Molecular Catalysis B: Enzymatic
- Vol. 11 (2-3) , 63-69
Stabilization of a β-glucosidase from Aspergillus niger by binding to an amine agarose gel
- 1 January 1993
- Published by Wiley in Journal of Chemical Technology & Biotechnology
- Vol. 57 (4) , 379-385
Pectinlyase immobilization on epoxy supports for application in the food processing industry
The immobilization of a pectinlyase (PL, EC 4.2.2.3) contained in a commercial enzymic preparation was studied in view of its use for fruit pulp and juice processing. Two epoxy supports were tested for immobilization. These included Eupergit C (Rohm), a synthetic polymer, and γ‐alumina functionalized with γ‐glycidoxypropyltrimethoxysilane. In both biocatalysts, the catalytic response was not found to be high. The highest response in terms of immobilization yield and immobilized PL activity, however, was reported for Eupergit C (approx. 115 unit g−1 at optimum pH).
- 1 January 1993
- Published by Wiley in Journal of Chemical Technology & Biotechnology
- Vol. 57 (4) , 379-385
Pectinlyase immobilization on epoxy supports for application in the food processing industry
The immobilization of a pectinlyase (PL, EC 4.2.2.3) contained in a commercial enzymic preparation was studied in view of its use for fruit pulp and juice processing. Two epoxy supports were tested for immobilization. These included Eupergit C (Rohm), a synthetic polymer, and γ‐alumina functionalized with γ‐glycidoxypropyltrimethoxysilane. In both biocatalysts, the catalytic response was not found to be high. The highest response in terms of immobilization yield and immobilized PL activity, however, was reported for Eupergit C (approx. 115 unit g−1 at optimum pH).