Moustafa Elshafei
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Interests
Moustafa Elshafei has a total of 33 co-authors. Here are the top co-authors by number of shared publications:
- Mohammad Amro
Information & Computer Science Department (ICS), King Fahd University of Petroleum & Minerals (KFUPM), Dhahran 31261, Saudi Arabia
2 shared publications - Taha Fanoush
Computer Science Department, University of Benghazi, Benghazi, Libya
2 shared publications - Wasfi G. Al-Khatib
Information & Computer Science Department (ICS), King Fahd University of Petroleum & Minerals (KFUPM), Dhahran 31261, Saudi Arabia
2 shared publications - Abd AlKreem Bin Saleh Al-Zahrani
د. عبد الكريم الزهران
1 shared publication Abdalrahman M. Amer
British Univ, Zewail City Sci & Technol, Cairo, Egypt
1 shared publicationAbdelrahman Ibrahim
Zewail City of Science and Technology, 6th October City, Giza 12578, Egypt
1 shared publication
Latest Publications
- Open Access
- 19 October 2026
- Published by Elsevier in Results in Engineering
- Vol. 32
Machine-learning prediction of nitrogen oxides in a hydrogen-enriched industrial boiler
- 19 October 2026
- Published by Elsevier in Results in Engineering
- Vol. 32
Open AccessMachine-learning prediction of nitrogen oxides in a hydrogen-enriched industrial boiler
- Open Access
- 1 January 2025
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Access
- Vol. 13, 175047-175068
Mispronunciation Detection and Diagnosis for Young Arabic Learners Using Transfer Learning
- 1 January 2025
- Published by Institute of Electrical and Electronics Engineers (IEEE) in IEEE Access
- Vol. 13, 175047-175068
Open AccessMispronunciation Detection and Diagnosis for Young Arabic Learners Using Transfer Learning
- 18 December 2024
- Published by Springer Nature
- p. 28-40
Arabic Pronunciation Assessment for Saudi Arabian Students: Corpus Development and System Architecture
- 18 December 2024
- Published by Springer Nature
- p. 28-40
Arabic Pronunciation Assessment for Saudi Arabian Students: Corpus Development and System Architecture
- Open Access
- 27 May 2024
- Published by Springer Nature in Scientific Reports
- Vol. 14 (1) , 1-19
Network pharmacology, molecular docking, and dynamics analyses to predict the antiviral activity of ginger constituents against coronavirus infection
COVID-19 is a global pandemic that caused a dramatic loss of human life worldwide, leading to accelerated research for antiviral drug discovery. Herbal medicine is one of the most commonly used alternative medicine for the prevention and treatment of many conditions including respiratory system diseases. In this study, a computational pipeline was employed, including network pharmacology, molecular docking simulations, and molecular dynamics simulations, to analyze the common phytochemicals of ginger rhizomes and identify candidate constituents as viral inhibitors. Furthermore, experimental assays were performed to analyze the volatile and non-volatile compounds of ginger and to assess the antiviral activity of ginger oil and hydroalcoholic extract. Network pharmacology analysis showed that ginger compounds target human genes that are involved in related cellular processes to the viral infection. Docking analysis highlighted five pungent compounds and zingiberenol as potential inhibitors for the main protease (Mpro), spike receptor-binding domain (RBD), and human angiotensin-converting enzyme 2 (ACE2). Then, (6)-gingerdiacetate was selected for molecular dynamics (MD) simulations as it exhibited the best binding interactions and free energies over the three target proteins. Trajectories analysis of the three complexes showed that RBD and ACE2 complexes with the ligand preserved similar patterns of root mean square deviation (RMSD) and radius of gyration (Rg) values to their respective native structures. Finally, experimental validation of the ginger hydroalcoholic extract confirmed the existence of (6)-gingerdiacetate and revealed the strong antiviral activity of the hydroalcoholic extract with IC $$_{50}$$ of 2.727 $$\upmu \hbox {g}/\hbox {ml}$$ . Our study provides insights into the potential antiviral activity of (6)-gingerdiacetate that may enhance the host immune response and block RBD binding to ACE2, thereby, inhibiting SARS-CoV-2 infection.- 27 May 2024
- Published by Springer Nature in Scientific Reports
- Vol. 14 (1) , 1-19
Open AccessNetwork pharmacology, molecular docking, and dynamics analyses to predict the antiviral activity of ginger constituents against coronavirus infection
COVID-19 is a global pandemic that caused a dramatic loss of human life worldwide, leading to accelerated research for antiviral drug discovery. Herbal medicine is one of the most commonly used alternative medicine for the prevention and treatment of many conditions including respiratory system diseases. In this study, a computational pipeline was employed, including network pharmacology, molecular docking simulations, and molecular dynamics simulations, to analyze the common phytochemicals of ginger rhizomes and identify candidate constituents as viral inhibitors. Furthermore, experimental assays were performed to analyze the volatile and non-volatile compounds of ginger and to assess the antiviral activity of ginger oil and hydroalcoholic extract. Network pharmacology analysis showed that ginger compounds target human genes that are involved in related cellular processes to the viral infection. Docking analysis highlighted five pungent compounds and zingiberenol as potential inhibitors for the main protease (Mpro), spike receptor-binding domain (RBD), and human angiotensin-converting enzyme 2 (ACE2). Then, (6)-gingerdiacetate was selected for molecular dynamics (MD) simulations as it exhibited the best binding interactions and free energies over the three target proteins. Trajectories analysis of the three complexes showed that RBD and ACE2 complexes with the ligand preserved similar patterns of root mean square deviation (RMSD) and radius of gyration (Rg) values to their respective native structures. Finally, experimental validation of the ginger hydroalcoholic extract confirmed the existence of (6)-gingerdiacetate and revealed the strong antiviral activity of the hydroalcoholic extract with IC $$_{50}$$ of 2.727 $$\upmu \hbox {g}/\hbox {ml}$$ . Our study provides insights into the potential antiviral activity of (6)-gingerdiacetate that may enhance the host immune response and block RBD binding to ACE2, thereby, inhibiting SARS-CoV-2 infection. - Open Access
- 26 September 2021
- Published by Akademia Baru Publishing in Journal of Advanced Research in Fluid Mechanics and Thermal Sciences
- Vol. 87 (2) , 17-26
Numerical Investigation for The Valorization of Waste from HMD Cell Using Electrodialysis
The Hydromagnetic desalination (HMD) system is a continuous process with several advantages, including a high water recovery ratio, and can be favored economically by producing several industrial byproducts instead of discharging the highly concentrated brine to the environment. In the current work, the ions concentration in the Electrodialysis (ED) technique is simulated using COMSOL Multiphysics V.5.2 software. The ED cell simulated in this paper contains two selective membranes (anion and cation) with a width of 0.25 mm each. The salt is to be taken away in the middle domain. The cell operation has been simulated to separate the sodium and chlorine ions from the HMD brine waste solution at 40 or 55ºC temperatures at different voltages and concentrations. In this two-dimensional model, the Nernst-Plank equation has been used to describe ion flux and charge transport in the electrolyte solution. Secondary current distribution theory and the electroneutrality condition have been used in the mathematical model. Finally, Donnan equations have been used to provide the exact fulfillment of boundary conditions for constant voltage mode. The simulation shows that the highest efficiency is obtained at high temperatures and voltage with the lowest feed concentration. Finally, the results have been validated using experimental data from the literature, and a satisfying agreement has been found.
- 26 September 2021
- Published by Akademia Baru Publishing in Journal of Advanced Research in Fluid Mechanics and Thermal Sciences
- Vol. 87 (2) , 17-26
Open AccessNumerical Investigation for The Valorization of Waste from HMD Cell Using Electrodialysis
The Hydromagnetic desalination (HMD) system is a continuous process with several advantages, including a high water recovery ratio, and can be favored economically by producing several industrial byproducts instead of discharging the highly concentrated brine to the environment. In the current work, the ions concentration in the Electrodialysis (ED) technique is simulated using COMSOL Multiphysics V.5.2 software. The ED cell simulated in this paper contains two selective membranes (anion and cation) with a width of 0.25 mm each. The salt is to be taken away in the middle domain. The cell operation has been simulated to separate the sodium and chlorine ions from the HMD brine waste solution at 40 or 55ºC temperatures at different voltages and concentrations. In this two-dimensional model, the Nernst-Plank equation has been used to describe ion flux and charge transport in the electrolyte solution. Secondary current distribution theory and the electroneutrality condition have been used in the mathematical model. Finally, Donnan equations have been used to provide the exact fulfillment of boundary conditions for constant voltage mode. The simulation shows that the highest efficiency is obtained at high temperatures and voltage with the lowest feed concentration. Finally, the results have been validated using experimental data from the literature, and a satisfying agreement has been found.
- Open Access
- 12 April 2021
- Published by Wiley in Journal of Energy
- Vol. 2021, 1-17
Study of Massive Floating Solar Panels over Lake Nasser
Recently, the technology of floating photovoltaic panels has demonstrated several advantages over land installations, including faster deployment, less maintenance cost, and higher efficiency. Lake Nasser is the second largest man-made freshwater lake in the world with a surface area of almost 5000 square km. Being in one of the hottest areas in the world, evaporation of water causes loss of very precious and scarce resources: freshwater. Fortunately, the lake is also located in a very rich area in solar energy. This paper presents a study to utilize Lake Nassers surface for massive production of solar energy, while significantly reducing the loss of water by evaporation from the lake surface. The project has the potential to be one of the largest producers of low-cost clean electric energy in the world for Europe and the Middle East and North Africa (MENA) region, especially with the ongoing efforts to connect the North African countries with the European super power grid. The study shows that the first phase of the project is expected to deliver about 16 of European need of electricity and save about 3 billion m3 of freshwater. The subsequent phases will provide low-cost green energy to replace the combustible fuels in Europe by 2045, while saving up to 10-12 billion m3 of freshwater lost by evaporation from Lake Nasser.
- 12 April 2021
- Published by Wiley in Journal of Energy
- Vol. 2021, 1-17
Open AccessStudy of Massive Floating Solar Panels over Lake Nasser
Recently, the technology of floating photovoltaic panels has demonstrated several advantages over land installations, including faster deployment, less maintenance cost, and higher efficiency. Lake Nasser is the second largest man-made freshwater lake in the world with a surface area of almost 5000 square km. Being in one of the hottest areas in the world, evaporation of water causes loss of very precious and scarce resources: freshwater. Fortunately, the lake is also located in a very rich area in solar energy. This paper presents a study to utilize Lake Nassers surface for massive production of solar energy, while significantly reducing the loss of water by evaporation from the lake surface. The project has the potential to be one of the largest producers of low-cost clean electric energy in the world for Europe and the Middle East and North Africa (MENA) region, especially with the ongoing efforts to connect the North African countries with the European super power grid. The study shows that the first phase of the project is expected to deliver about 16 of European need of electricity and save about 3 billion m3 of freshwater. The subsequent phases will provide low-cost green energy to replace the combustible fuels in Europe by 2045, while saving up to 10-12 billion m3 of freshwater lost by evaporation from Lake Nasser.
- 1 July 2020
- Published by Desalination Publications in Desalination and Water Treatment
- Vol. 193, 11-18
Evaluation of capacitive deionization desalination technology for irrigation
- 1 July 2020
- Published by Desalination Publications in Desalination and Water Treatment
- Vol. 193, 11-18
Evaluation of capacitive deionization desalination technology for irrigation
- Open Access
- 2 October 2019
- Published by IntechOpen
Distributed Optimization of Multi-Robot Motion with Time-Energy Criterion
This paper is an application of a special case of distributed optimization problem. It is applied on optimizing the motion of multiple robot systems. The problem is decomposed into L subproblems with L being the number of robot systems. This decomposition reduces the problem to solving a single robot problem. The optimization problem is solved via a distributed algorithm, utilizing subgradient method. A global objective function is set as the sum of individual robot objectives in time and energy. Constraints are divided into two sets, namely, robot-individual constraints and robots’ interactions (collision) constraints. The approach is applied for the case of wheeled mobile robots: we are able to generate in parallel for each robot an optimized control input trajectory and then illustrate it in simulation examples.
- 2 October 2019
- Published by IntechOpen
Open AccessDistributed Optimization of Multi-Robot Motion with Time-Energy Criterion
This paper is an application of a special case of distributed optimization problem. It is applied on optimizing the motion of multiple robot systems. The problem is decomposed into L subproblems with L being the number of robot systems. This decomposition reduces the problem to solving a single robot problem. The optimization problem is solved via a distributed algorithm, utilizing subgradient method. A global objective function is set as the sum of individual robot objectives in time and energy. Constraints are divided into two sets, namely, robot-individual constraints and robots’ interactions (collision) constraints. The approach is applied for the case of wheeled mobile robots: we are able to generate in parallel for each robot an optimized control input trajectory and then illustrate it in simulation examples.