Alaa Al-Saruri
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Alaa Al-Saruri has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Abeer M. Mahmoud
Division of Endocrinology, Department of Medicine, University of Illinois Chicago, Chicago, IL 60612, USA
1 shared publication - Emily Sible
Centre International de Recherche en Infectiologie, CIRI, Inserm, U1111, 69007 Lyon, France
1 shared publication - Hasan Mohamad Bamahros
University of Hail
1 shared publication - Umaima Al-Alem
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, Illinois, United States of America
1 shared publication - Uzma Hasan
Centre International de recherche en Infectiologie, CIRI, Inserm, U1111, Lyon, France
1 shared publication
Latest Publications
- Open Access
Understanding the Role of Toll-Like Receptors 9 in Breast Cancer
Breast cancer is a significant global issue, ranking as the second most common cancer among women worldwide and a leading cause of cancer-related deaths. Although the exact causes of this increase remain unclear, factors such as genetics, epigenetics, obesity, sedentary lifestyle, tobacco use, and vitamin D deficiency have been implicated. The Toll-like receptor 9 (TLR9) is recognized for its role in inflammation and innate immunity; however, its specific involvement in breast cancer pathogenesis requires further investigation. This study aims to systematically review the existing literature on TLR9 expression in normal and cancerous breast tissue, providing current knowledge and identifying gaps. Relevant articles in English were from PubMed, Scopus, and Google Scholar, with the inclusion criteria focusing on studies evaluating TLR9 mRNA and protein expression. The review found that TLR9 mRNA and protein exhibit variable expressions in both normal and cancerous breast tissue, highlighting the need for further research to clarify TLR9’s role in breast cancer.
Open AccessUnderstanding the Role of Toll-Like Receptors 9 in Breast Cancer
Breast cancer is a significant global issue, ranking as the second most common cancer among women worldwide and a leading cause of cancer-related deaths. Although the exact causes of this increase remain unclear, factors such as genetics, epigenetics, obesity, sedentary lifestyle, tobacco use, and vitamin D deficiency have been implicated. The Toll-like receptor 9 (TLR9) is recognized for its role in inflammation and innate immunity; however, its specific involvement in breast cancer pathogenesis requires further investigation. This study aims to systematically review the existing literature on TLR9 expression in normal and cancerous breast tissue, providing current knowledge and identifying gaps. Relevant articles in English were from PubMed, Scopus, and Google Scholar, with the inclusion criteria focusing on studies evaluating TLR9 mRNA and protein expression. The review found that TLR9 mRNA and protein exhibit variable expressions in both normal and cancerous breast tissue, highlighting the need for further research to clarify TLR9’s role in breast cancer.