Alexandra A. Seas
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Alexandra A. Seas has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Adarsha P. Malla
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
1 shared publication - Graeme F. Woodworth
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
1 shared publication - Jeffrey A. Winkles
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland
1 shared publication - Nima Sharifai
Department of Pathology, University of Maryland School of Medicine , Baltimore, MD
1 shared publication - Pavlos Anastasiadis
Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland
1 shared publication
Latest Publications
- Open Access
- 1 June 2024
- Published by MDPI AG in Biomedicines
- Vol. 12 (6) , 1230
Microbubble-Enhanced Focused Ultrasound for Infiltrating Gliomas
Infiltrating gliomas are challenging to treat, as the blood-brain barrier significantly impedes the success of therapeutic interventions. While some clinical trials for high-grade gliomas have shown promise, patient outcomes remain poor. Microbubble-enhanced focused ultrasound (MB-FUS) is a rapidly evolving technology with demonstrated safety and efficacy in opening the blood-brain barrier across various disease models, including infiltrating gliomas. Initially recognized for its role in augmenting drug delivery, the potential of MB-FUS to augment liquid biopsy and immunotherapy is gaining research momentum. In this review, we will highlight recent advancements in preclinical and clinical studies that utilize focused ultrasound to treat gliomas and discuss the potential future uses of image-guided precision therapy using focused ultrasound.
- 1 June 2024
- Published by MDPI AG in Biomedicines
- Vol. 12 (6) , 1230
Open AccessMicrobubble-Enhanced Focused Ultrasound for Infiltrating Gliomas
Infiltrating gliomas are challenging to treat, as the blood-brain barrier significantly impedes the success of therapeutic interventions. While some clinical trials for high-grade gliomas have shown promise, patient outcomes remain poor. Microbubble-enhanced focused ultrasound (MB-FUS) is a rapidly evolving technology with demonstrated safety and efficacy in opening the blood-brain barrier across various disease models, including infiltrating gliomas. Initially recognized for its role in augmenting drug delivery, the potential of MB-FUS to augment liquid biopsy and immunotherapy is gaining research momentum. In this review, we will highlight recent advancements in preclinical and clinical studies that utilize focused ultrasound to treat gliomas and discuss the potential future uses of image-guided precision therapy using focused ultrasound.