Haritha Pavuluri
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Haritha Pavuluri has a total of 4 co-authors. Here are the top co-authors by number of shared publications:
- Wayne J. G. Hellstrom
Department of Urology, Tulane University School of Medicine , New Orleans, LA 70112
2 shared publications - Brendan Chester King
Tulane University School of Medicine
1 shared publication - Manesh Kumar Panner Selvam
Tulane University School of Medicine
1 shared publication - Zahra Bakhtiary
Department of Urology, Tulane University School of Medicine, New Orleans, LA 70112, USA
1 shared publication
Latest Publications
- 1 September 2025
- Published by Springer Nature
- p. 69-74
Various Surgical Approaches for Penile Prosthesis
- 1 September 2025
- Published by Springer Nature
- p. 69-74
Various Surgical Approaches for Penile Prosthesis
- Top Cited PapersOpen Access
Oxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches
Infertility is a prevalent global issue affecting approximately 17.5% of adults, with sole male factor contributing to 20–30% of cases. Oxidative stress (OS) is a critical factor in male infertility, disrupting the balance between reactive oxygen species (ROS) and antioxidants. This imbalance detrimentally affects sperm function and viability, ultimately impairing fertility. OS also triggers molecular changes in sperm, including DNA damage, lipid peroxidation, and alterations in protein expression, further compromising sperm functionality and potential fertilization. Diagnostic tools discussed in this review offer insights into OS markers, antioxidant levels, and intracellular ROS concentrations. By accurately assessing these parameters, clinicians can diagnose male infertility more effectively and thus tailor treatment plans to individual patients. Additionally, this review explores various treatment options for males with OS-associated infertility, such as empirical drugs, antioxidants, nanoantioxidants, and lifestyle modifications. By addressing the root causes of male infertility and implementing targeted interventions, clinicians can optimize treatment outcomes and enhance the chances of conception for couples struggling with infertility.
Top Cited PapersOpen AccessOxidative Stress-Associated Male Infertility: Current Diagnostic and Therapeutic Approaches
Infertility is a prevalent global issue affecting approximately 17.5% of adults, with sole male factor contributing to 20–30% of cases. Oxidative stress (OS) is a critical factor in male infertility, disrupting the balance between reactive oxygen species (ROS) and antioxidants. This imbalance detrimentally affects sperm function and viability, ultimately impairing fertility. OS also triggers molecular changes in sperm, including DNA damage, lipid peroxidation, and alterations in protein expression, further compromising sperm functionality and potential fertilization. Diagnostic tools discussed in this review offer insights into OS markers, antioxidant levels, and intracellular ROS concentrations. By accurately assessing these parameters, clinicians can diagnose male infertility more effectively and thus tailor treatment plans to individual patients. Additionally, this review explores various treatment options for males with OS-associated infertility, such as empirical drugs, antioxidants, nanoantioxidants, and lifestyle modifications. By addressing the root causes of male infertility and implementing targeted interventions, clinicians can optimize treatment outcomes and enhance the chances of conception for couples struggling with infertility.