Laura Perez-Mayo
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Laura Perez-Mayo has a total of 19 co-authors. Here are the top co-authors by number of shared publications:
- Ana Calzada-Reyes
Department of Clinical Neurophysiology, Institute of Legal Medicine, Independence Avenue, Plaza, Havana City, Cuba
1 shared publication Annette Valdés-Virués
Hermanos Ameijeiras Hospital
1 shared publicationAntonio Caballero-Moreno
Psychiatric Clinic “Gali Garcia”, National Hospital
1 shared publication- Deirel Paz-Linares
The Clinical Hospital of Chengdu Brain Sciences, University of Electronic Science and Technology of China, Chengdu, China
1 shared publication - Eduardo Aubert-Vazquez
The Clinical Hospital of Chengdu Brain Sciences Institute, University of Electronic Science andTechnology of China
1 shared publication Janet Perodin Hernandez
Cuban Centre for Neurosciences
1 shared publication
Latest Publications
- Open Access
EEG Signatures of COVID-19 Survival compared to close contacts and the Cuban EEG normative database
Background The EEG constitutes a powerful neuroimaging technique for assessing functional brain impairment in COVID-19 patients. Objective The current investigation compared the EEG among COVID-19 survivors, close contacts and the Cuban EEG normative database, using semi-quantitative visual EEG inspection, quantitative and the current source density measures EEG analysis. Methods The resting-state EEG activity, quantitative QEEG, and VARETA inverse solution, were evaluated in 173 subjects: 87 patients confirmed cases by the positive reverse transcription polymerase chain reaction (RT-PCR), 86 close contacts (negative PCR) and the Cuban EEG normative database. All patients were physical, neurological, and clinically assessed using neurological retrospective survey and version 2.1 of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN). Results The GTE score showed significant differences in terms of frequency scores of backgrounds rhythmic activity, diffuse slow activity, and focal abnormality. The QEEG analysis showed a pattern of abnormality with respect to the Cuban EEG normative values, displaying an excess of alpha and beta activities in the fronto-central-parietal areas in both groups. The anomalies, of COVID-19 patients and close contacts, differs in the right fronto-centro parietal area. The COVID 19 group differed-s from the close control group in theta band of the right parieto-central. The symptomatic group of COVID-19 patients differs from asymptomatic patients in delta and theta activities of the parieto-central region. The sources of activation using VARETA showed a difference in cortical activation patterns at alpha and beta frequencies in the groups studied with respect to the normative EEG database. In beta frequency were localized in right middle temporal gyrus in both groups and right angular gyrus in Covid 19 group only. In alpha band, the regions were the left supramarginal gyrus for Covid 19 group and the left superior temporal gyrus for Control group. Greater activation was found in the right middle temporal gyrus at alpha frequency in COVID-19 patients than in their close contacts. Conclusions Brain functions are impaired in long COVID-19 patients. QEEG and VARETA permit us to comprehend the susceptibility of particular brain regions exposed to viral illness. Highlights Background frequency abnormalities diffuse slow activity and focal abnormality associated with a pattern of excess oftheta, alpha and beta energies in in the right fronto-centro-parietal regions in QEEG analysis characterizedCOVID-19 patients. Patients with COVID-19 show more alpha and beta EEG activities related to normative EEG database. Patients with COVID-19 and close contacts show high cortical activation in temporo-parietal areas in alpha and beta bands compared to normative EEG database. Patients with COVID-19 (positive PCR) have high activation in the right middle frontal gyrus for alpha band related to close contacts.
Open AccessEEG Signatures of COVID-19 Survival compared to close contacts and the Cuban EEG normative database
Background The EEG constitutes a powerful neuroimaging technique for assessing functional brain impairment in COVID-19 patients. Objective The current investigation compared the EEG among COVID-19 survivors, close contacts and the Cuban EEG normative database, using semi-quantitative visual EEG inspection, quantitative and the current source density measures EEG analysis. Methods The resting-state EEG activity, quantitative QEEG, and VARETA inverse solution, were evaluated in 173 subjects: 87 patients confirmed cases by the positive reverse transcription polymerase chain reaction (RT-PCR), 86 close contacts (negative PCR) and the Cuban EEG normative database. All patients were physical, neurological, and clinically assessed using neurological retrospective survey and version 2.1 of the Schedules for Clinical Assessment in Neuropsychiatry (SCAN). Results The GTE score showed significant differences in terms of frequency scores of backgrounds rhythmic activity, diffuse slow activity, and focal abnormality. The QEEG analysis showed a pattern of abnormality with respect to the Cuban EEG normative values, displaying an excess of alpha and beta activities in the fronto-central-parietal areas in both groups. The anomalies, of COVID-19 patients and close contacts, differs in the right fronto-centro parietal area. The COVID 19 group differed-s from the close control group in theta band of the right parieto-central. The symptomatic group of COVID-19 patients differs from asymptomatic patients in delta and theta activities of the parieto-central region. The sources of activation using VARETA showed a difference in cortical activation patterns at alpha and beta frequencies in the groups studied with respect to the normative EEG database. In beta frequency were localized in right middle temporal gyrus in both groups and right angular gyrus in Covid 19 group only. In alpha band, the regions were the left supramarginal gyrus for Covid 19 group and the left superior temporal gyrus for Control group. Greater activation was found in the right middle temporal gyrus at alpha frequency in COVID-19 patients than in their close contacts. Conclusions Brain functions are impaired in long COVID-19 patients. QEEG and VARETA permit us to comprehend the susceptibility of particular brain regions exposed to viral illness. Highlights Background frequency abnormalities diffuse slow activity and focal abnormality associated with a pattern of excess oftheta, alpha and beta energies in in the right fronto-centro-parietal regions in QEEG analysis characterizedCOVID-19 patients. Patients with COVID-19 show more alpha and beta EEG activities related to normative EEG database. Patients with COVID-19 and close contacts show high cortical activation in temporo-parietal areas in alpha and beta bands compared to normative EEG database. Patients with COVID-19 (positive PCR) have high activation in the right middle frontal gyrus for alpha band related to close contacts.