Daniel Alexandru Suru
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Daniel Alexandru Suru has a total of 11 co-authors. Here are the top co-authors by number of shared publications:
- Dan Alexandru Toc
Department of Microbiology, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania
1 shared publication - Eugenio Pin
Medical Emergency Service, Trieste University Hospital (ASUGI), 34125 Trieste, Italy
1 shared publication - Gianfranco Sanson
University of Trieste
1 shared publication - Jacopo Monticelli
Infectious Disease Unit, Trieste University Hospital, Trieste, Italy
1 shared publication - Lory Saveria Crocè
Clinical Department of Medical, Surgical and Health Sciences, Trieste University, 34129 Trieste, Italy
1 shared publication - Marina Busetti
Microbiology Unit, Trieste University Hospital (ASUGI), Trieste, Italy
1 shared publication
Latest Publications
- Open Access
- 27 June 2024
- Published by MDPI AG in Antibiotics
- Vol. 13 (7) , 601
Risk Factors for 30-Day Mortality in Nosocomial Enterococcal Bloodstream Infections
Enterococci commonly cause nosocomial bloodstream infections (BSIs), and the global incidence of vancomycin-resistant enterococci (VRE) BSIs is rising. This study aimed to assess the risk factors for enterococcal BSIs and 30-day mortality, stratified by Enterococcus species, vancomycin resistance, and treatment appropriateness. We conducted a retrospective cohort study (2014–2021) including all hospitalized adult patients with at least one blood culture positive for Enterococcus faecalis or Enterococcus faecium. We included 584 patients with enterococcal BSI: 93 were attributed to vancomycin-resistant E. faecium. The overall 30-day mortality was 27.5%; higher in cases of BSI due to vancomycin-resistant E. faecium (36.6%) and vancomycin-sensitive E. faecium (31.8%) compared to E. faecalis BSIs (23.2%) (p = 0.016). This result was confirmed by multivariable Cox analysis. Independent predictors of increased mortality included the PITT score, complicated bacteremia, and age (HR = 1.269, p < 0.001; HR = 1.818, p < 0.001; HR = 1.022, p = 0.005, respectively). Conversely, male gender, consultation with infectious disease (ID) specialists, and appropriate treatment were associated with reduced mortality (HR = 0.666, p = 0.014; HR = 0.504, p < 0.001; HR = 0.682, p = 0.026, respectively). In conclusion, vancomycin-resistant E. faecium bacteremia is independently associated with a higher risk of 30-day mortality.
- 27 June 2024
- Published by MDPI AG in Antibiotics
- Vol. 13 (7) , 601
Open AccessRisk Factors for 30-Day Mortality in Nosocomial Enterococcal Bloodstream Infections
Enterococci commonly cause nosocomial bloodstream infections (BSIs), and the global incidence of vancomycin-resistant enterococci (VRE) BSIs is rising. This study aimed to assess the risk factors for enterococcal BSIs and 30-day mortality, stratified by Enterococcus species, vancomycin resistance, and treatment appropriateness. We conducted a retrospective cohort study (2014–2021) including all hospitalized adult patients with at least one blood culture positive for Enterococcus faecalis or Enterococcus faecium. We included 584 patients with enterococcal BSI: 93 were attributed to vancomycin-resistant E. faecium. The overall 30-day mortality was 27.5%; higher in cases of BSI due to vancomycin-resistant E. faecium (36.6%) and vancomycin-sensitive E. faecium (31.8%) compared to E. faecalis BSIs (23.2%) (p = 0.016). This result was confirmed by multivariable Cox analysis. Independent predictors of increased mortality included the PITT score, complicated bacteremia, and age (HR = 1.269, p < 0.001; HR = 1.818, p < 0.001; HR = 1.022, p = 0.005, respectively). Conversely, male gender, consultation with infectious disease (ID) specialists, and appropriate treatment were associated with reduced mortality (HR = 0.666, p = 0.014; HR = 0.504, p < 0.001; HR = 0.682, p = 0.026, respectively). In conclusion, vancomycin-resistant E. faecium bacteremia is independently associated with a higher risk of 30-day mortality.