Arezoo Dehghani
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Arezoo Dehghani has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Ali Akbari
Solid Tumor Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran
1 shared publication Gholam Reza Mahdavinia
Polymer Research Laboratory, Department of Chemistry, Faculty of Science University of Maragheh Maragheh Iran
1 shared publicationHessam Jafari
Polymer Research Laboratory, Department of Chemistry, Faculty of Science University of Maragheh Maragheh Iran
1 shared publicationKhashayar Najafzadeh
Tchnology Unit of Tarbiat Modares Science and Technology Park Farvardin Group Tehran Iran
1 shared publicationParisa Labib
Polymer Research Laboratory, Department of Chemistry, Faculty of Science University of Maragheh Maragheh Iran
1 shared publication- Raoofeh Sattari Nobarzad
Polymer Research Laboratory, Department of Chemistry, Faculty of Science University of Maragheh Maragheh Iran
1 shared publication
Latest Publications
- 24 June 2024
- Published by Wiley in Applied Organometallic Chemistry
- Vol. 38 (9)
Chitosan‐based pH‐sensitive antibacterial bionanocomposites with laponite immobilized silver nanoparticles for delivery of sunitinib maleate to breast cancers
In this work, new pH‐sensitive and antibacterial drug carrier systems based on silver nanoparticles (AgNPs) embedded in the interlayer of laponite (Lap) in the presence of chitosan (CTS) for the controllable release of sunitinib maleate (STM) were developed. Silver ions and sunitinib maleate were first loaded into Lap, and the CTS‐based hybrid bionanocomposite carrier (Lap@CTS@AgNPs@STM) was obtained in the presence of citric acid as a cross‐linker agent. The successful preparation of nanocarrier and Ag NPs formation was thoroughly confirmed using techniques such as FTIR, XRD, TGA, SEM, and TEM. TEM images illustrated the excellent distribution of Ag NPs in the structure of Lap@CTS@AgNPs. The as‐prepared samples showed a pH‐sensitive anticancer drug release behavior. The STM release mechanism was studied using Korsmeyer–Peppas and Higuchi kinetic models. Furthermore, the in vitro cytotoxicity and antibacterial tests were carried out against both bacteria S. aureus and E. coli and MCF‐7 cell lines, respectively, to prove the effectiveness of synthesized samples as multifunctional carrier systems for biomedical applications.
- 24 June 2024
- Published by Wiley in Applied Organometallic Chemistry
- Vol. 38 (9)
Chitosan‐based pH‐sensitive antibacterial bionanocomposites with laponite immobilized silver nanoparticles for delivery of sunitinib maleate to breast cancers
In this work, new pH‐sensitive and antibacterial drug carrier systems based on silver nanoparticles (AgNPs) embedded in the interlayer of laponite (Lap) in the presence of chitosan (CTS) for the controllable release of sunitinib maleate (STM) were developed. Silver ions and sunitinib maleate were first loaded into Lap, and the CTS‐based hybrid bionanocomposite carrier (Lap@CTS@AgNPs@STM) was obtained in the presence of citric acid as a cross‐linker agent. The successful preparation of nanocarrier and Ag NPs formation was thoroughly confirmed using techniques such as FTIR, XRD, TGA, SEM, and TEM. TEM images illustrated the excellent distribution of Ag NPs in the structure of Lap@CTS@AgNPs. The as‐prepared samples showed a pH‐sensitive anticancer drug release behavior. The STM release mechanism was studied using Korsmeyer–Peppas and Higuchi kinetic models. Furthermore, the in vitro cytotoxicity and antibacterial tests were carried out against both bacteria S. aureus and E. coli and MCF‐7 cell lines, respectively, to prove the effectiveness of synthesized samples as multifunctional carrier systems for biomedical applications.