Victoria K. Lam
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Victoria K. Lam has a total of 3 co-authors. Here are the top co-authors by number of shared publications:
- Donna Cerabona
University of Notre Dame; Notre Dame, IN USA
1 shared publication - Robert A. Schulz
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
1 shared publication - Tsuyoshi Tokusumi
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
1 shared publication
Latest Publications
- Open Access
- 27 October 2010
- Published by Taylor & Francis in Fly
- Vol. 4 (4) , 338-343
Specific cell ablation in Drosophila using the toxic viral protein M2(H37A)
The expression of toxic viral proteins for the purpose of eliminating distinct populations of cells, while leaving the rest of an organism unaffected, is a valuable method for analyzing development. Using the Gal4-UAS system, we employed the M2(H37A) toxic ion channel of the influenza-A virus to selectively ablate the Drosophila eye-antennal imaginal discs, hemocytes, dorsal vessel and nervous tissue, and comparatively monitored the effects of expressing the apoptosis-promoting protein Reaper in identical cell populations. In this report, we demonstrate the effectiveness of M2(H37A)-mediated ablation as a new means to selectively eliminate cells of interest during Drosophila development.
- 27 October 2010
- Published by Taylor & Francis in Fly
- Vol. 4 (4) , 338-343
Open AccessSpecific cell ablation in Drosophila using the toxic viral protein M2(H37A)
The expression of toxic viral proteins for the purpose of eliminating distinct populations of cells, while leaving the rest of an organism unaffected, is a valuable method for analyzing development. Using the Gal4-UAS system, we employed the M2(H37A) toxic ion channel of the influenza-A virus to selectively ablate the Drosophila eye-antennal imaginal discs, hemocytes, dorsal vessel and nervous tissue, and comparatively monitored the effects of expressing the apoptosis-promoting protein Reaper in identical cell populations. In this report, we demonstrate the effectiveness of M2(H37A)-mediated ablation as a new means to selectively eliminate cells of interest during Drosophila development.