Current Organizations / Institutes

The organizations/institutes from the scholar's latest article


Cheng-Yu Wang has a total of 9 co-authors. Here are the top co-authors by number of shared publications:


Latest Publications

  • Open Access

    Fabrication of a Microfluidic-Based Device Coated with Polyelectrolyte-Capped Titanium Dioxide to Couple High-Performance Liquid Chromatography with Inductively Coupled Plasma Mass Spectrometry for Mercury Speciation

    by Ji-Hao Chen, Yu-Ting Luo, Yi-An Su, Yan-Ren Ke, Ming-Jay Deng, Wei-Yu Chen, Cheng-Yu Wang, Jia-Lin Tsai, Cheng-Hsing Lin, Tsung-Ting Shih

    Mercury (Hg) is a toxic element which impacts on biological systems and ecosystems. Because the toxicity of Hg species is highly dependent on their concentration levels and chemical forms, the sensitive identification of the chemical forms of Hg—i.e., Hg speciation—is of major significance in providing meaningful information about the sources of Hg exposure. In this study, a microfluidic-based device made of high-clarity poly(methyl methacrylate) (PMMA) was fabricated. Then, titanium dioxide nanoparticles (nano-TiO2s) were attached to the treated channel’s interior with the aid of poly(diallyldimethylammonium chloride) (PDADMAC). After coupling the nano-TiO2-coated microfluidic-based photocatalyst-assisted reduction device (the nano-TiO2-coated microfluidic-based PCARD) with high-performance liquid chromatography (HPLC) and inductively coupled plasma mass spectrometry (ICP-MS), a selective and sensitive, hyphenated system for Hg speciation was established. Validation procedures demonstrated that the method could be satisfactorily applied to the determination of mercury ions (Hg2+) and methylmercury ions (CH3Hg+) in both human urine and water samples. Remarkably, the zeta potential measured clearly indicated that the PDADMAC-capped nano-TiO2s with a predominance of positive charges indeed provided a steady force for firm attachment to the negatively charged device channel. The cause of the durability of the nano-TiO2-coated microfluidic-based PCARD was clarified thus.


  • Open Access

    Fabrication of a Microfluidic-Based Device Coated with Polyelec-Trolyte-Capped-Titanium Dioxide to Couple High-Performance Liquid Chromatography with Inductively Coupled Plasma-Mass Spectrometry for Mercury Speciation

    by Ji-Hao Chen, Yu-Ting Luo, Yi-An Su, Yan-Ren Ke, Ming-Jay Deng, Wei-Yu Chen, Cheng-Yu Wang, Jia-Lin Tsai, Cheng-Hsing Lin, Tsung-Ting Shih

    Mercury (Hg) is a toxic element impacting on biological systems and ecosystems. Because the toxicity of Hg species is highly dependent on concentration levels and chemical forms, sensitive identification of chemical forms for Hg, i.e., Hg speciation, is of major significance in providing meaningful information about the source of Hg exposure. In this study, a microfluidic-based device made of high clarity poly(methyl methacrylate) (PMMA) was fabricated. Then titanium dioxide nanoparticles (nano-TiO2) were attached to the treated channel interior with the aid of poly(diallyldimethylammonium chloride) (PDADMAC). After coupling the nano-TiO2-coated microfluidic-based photocatalyst-assisted reduction device (the nano-TiO2-coated microfluid-ic-based PCARD) with high-performance liquid chromatography (HPLC) and inductively coupled plasma-mass spectrometry (ICP-MS), a selective and sensitive hyphenated system for Hg specia-tion was established. Validation procedures demonstrated that the method could be satisfactorily applied to the determination of mercuric ion (Hg2+) and methylmercury ion (CH3Hg+) in both human urine and water samples. Remarkably, the zeta potential measured clearly indicated the PDADMAC-capped nano-TiO2 with predominance of positive charges indeed provided steady force for firm attachment to the negatively charged device channel. The cause for the durability of the nano-TiO2-coated microfluidic-based PCARD was clarified thus.