Mubarak Nasir M. Almulhim
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Mubarak Nasir M. Almulhim has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Ali Mohammed A. Aljeshi
College of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia
1 shared publication - Asmaa Fady Sharif
Forensic Medicine and Clinical Toxicology Department, Faculty of medicine, Tanta University, Tanta, Egypt
1 shared publication - Hadi Mohamed A. Almosabeh
College of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia
1 shared publication - Khalid A. Al-Mulhim
Emergency Medicine Department, King Fahad Medical City, Sulimaniyah, Riyadh 12231, Saudi Arabia
1 shared publication - Mohammed Essam A. Alshammasy
College of Medicine, Dar AL-Uloom University, Al Falah, Riyadh 13314, Saudi Arabia
1 shared publication - Shahd AlNasser
Saudi Food and Drug Authority, Hittin, Riyadh 13513, Saudi Arabia
1 shared publication
Latest Publications
- Open Access
Predictors of Serotonin Syndrome in Acute Poisoning with 5-Hydroxytryptamine Modulators
5-Hydroxytryptamine (5-HT) modulators are commonly prescribed medications with potentially life-threatening outcomes, particularly serotonin syndrome (SS). Early prediction of SS is critical not only to avoid lethal drug combinations but also to initiate appropriate treatment. The present work aimed to recognize the significant predictors of SS through a retrospective cross-sectional study that was conducted among patients exposed to an overdose of 5-HT modulators and admitted to a poison control center where 112 patients were enrolled. Of them, 21 patients were diagnosed with SS, and 66.7% of patients with SS were exposed to long-term co-ingestion. There was a noticeable surge in SS between April and May, and 52.4% of patients who suffered from SS were admitted after suicidal exposure (p < 0.05). Patients with SS showed severe presentation indicated by high-grade poison severity scores (PSS) and low Glasgow coma scales (GCS). PSS was a significant predictor of SS with an area under the curve of 0.879. PCO2, pulse, GCS, HCO3, and erythrocytic count were other significant predictors of SS. Combinations of serotonergic agents increase the likelihood of developing SS. Clinicians should be vigilant when prescribing a combination of serotonergic therapy, particularly for patients on illicit sympathomimetic and over-the-counter medications like dextromethorphan.
Open AccessPredictors of Serotonin Syndrome in Acute Poisoning with 5-Hydroxytryptamine Modulators
5-Hydroxytryptamine (5-HT) modulators are commonly prescribed medications with potentially life-threatening outcomes, particularly serotonin syndrome (SS). Early prediction of SS is critical not only to avoid lethal drug combinations but also to initiate appropriate treatment. The present work aimed to recognize the significant predictors of SS through a retrospective cross-sectional study that was conducted among patients exposed to an overdose of 5-HT modulators and admitted to a poison control center where 112 patients were enrolled. Of them, 21 patients were diagnosed with SS, and 66.7% of patients with SS were exposed to long-term co-ingestion. There was a noticeable surge in SS between April and May, and 52.4% of patients who suffered from SS were admitted after suicidal exposure (p < 0.05). Patients with SS showed severe presentation indicated by high-grade poison severity scores (PSS) and low Glasgow coma scales (GCS). PSS was a significant predictor of SS with an area under the curve of 0.879. PCO2, pulse, GCS, HCO3, and erythrocytic count were other significant predictors of SS. Combinations of serotonergic agents increase the likelihood of developing SS. Clinicians should be vigilant when prescribing a combination of serotonergic therapy, particularly for patients on illicit sympathomimetic and over-the-counter medications like dextromethorphan.