Igor Cordeiro Fernandes
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Igor Cordeiro Fernandes has a total of 15 co-authors. Here are the top co-authors by number of shared publications:
- Aldo Venuti
HPV-UNIT-UOSD Tumor Immunology and Immunotherapy, IRCCS Regina Elena National Cancer Institute, 00144 Rome, Italy
1 shared publication - Ana Pavla Almeida Diniz Gurgel
Laboratory of Molecular Genetics (LAGEM), Department of Engineering and Environment, Federal, University of Paraiba, Rio Tinto, 58297-000 Paraiba, Brazil, Brazil
1 shared publication - Anderson Felix dos Santos
Posgraduate Program in Therapeutical Innovation, Federal University of Pernambuco, 50670-901, Recife, Brazil, Brazil
1 shared publication - André Luiz dos Santos Jesus
Biotecnology and Diversity Post-Graduate Program, Federal Institut of Mato Grosso, Cuiabá, 78043-409 Mato Grosso, Brazil, Brazil
1 shared publication - Antonio Carlos de Freitas
Laboratory of Molecular Studies and Experimental Therapy—LEMTE, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, Brazil
1 shared publication - Douglas de Lucena Silva
Molecular and Celular Biology Post-Graduate Program, (PPGBCM), Federal, University of Paraiba, João Pessoa, 58297-000 Paraíba, Brazil, Brazil
1 shared publication
Latest Publications
- Open Access
- 14 August 2024
- Published by MDPI AG in Preprints.org
Detection of Human Papillomavirus (HPV) and Bovine Leukemia Virus (BLV) in Breast Cancer Patients from Northeastern Brazil
This study evaluated the presence of Human Papillomavirus (HPV) and Bovine Leukemia Virus (BLV) DNA in breast cancer (BC) samples from women in Northeastern Brazil. We analyzed 186 formalin-fixed, paraffin-embedded tissue block samples using PCR and qPCR to detect HPV and BLV DNA. BLV DNA was not detected in any BC patients. However, HPV DNA was found in 46.2\% of the BC samples: 44.6\% were positive for HPV16, 3.5\% for HPV31, and 2\% were coinfected with HPV16 and HPV31. Additionally, we found an association between HPV-positive BC and Ki-67 expression (P=0.03, OR=1.85; CI=1.02-3.34), as well as between HPV31-positive BC and mitotic index (P=0.047). Although BLV was not detected in BC patients from Northeastern Brazil, the association between HPV and cell proliferation markers warrants further investigation, as HPV may contribute to the aggressiveness of BC in these patients.
- 14 August 2024
- Published by MDPI AG in Preprints.org
Open AccessDetection of Human Papillomavirus (HPV) and Bovine Leukemia Virus (BLV) in Breast Cancer Patients from Northeastern Brazil
This study evaluated the presence of Human Papillomavirus (HPV) and Bovine Leukemia Virus (BLV) DNA in breast cancer (BC) samples from women in Northeastern Brazil. We analyzed 186 formalin-fixed, paraffin-embedded tissue block samples using PCR and qPCR to detect HPV and BLV DNA. BLV DNA was not detected in any BC patients. However, HPV DNA was found in 46.2\% of the BC samples: 44.6\% were positive for HPV16, 3.5\% for HPV31, and 2\% were coinfected with HPV16 and HPV31. Additionally, we found an association between HPV-positive BC and Ki-67 expression (P=0.03, OR=1.85; CI=1.02-3.34), as well as between HPV31-positive BC and mitotic index (P=0.047). Although BLV was not detected in BC patients from Northeastern Brazil, the association between HPV and cell proliferation markers warrants further investigation, as HPV may contribute to the aggressiveness of BC in these patients.