Hafsa Mguild
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Hafsa Mguild has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Aboubakr Khazaz
Molecular Bacteriology Laboratory, Institut Pasteur du Maroc, Casablanca 20360, Morocco
2 shared publications - Amine Aiddi
Microbiology Unit, Laboratory of Ecology and Environment, Department of Biology, Faculty of Sciences Ben M’sik, Hassan II University, Casablanca, Morocco
2 shared publications - Ilham Zerdani
Ecology and Environment Laboratory, Faculty of Sciences Ben M’sik, Hassan II University of Casablanca, Casablanca, Morocco
2 shared publications - Kaotar Nayme
Laboratoire de bactériologie moléculaire , Institut Pasteur du Maroc , Casablanca , Morocco , pasteur.ma
2 shared publications - Adil El Hamouchi
Genomic Sequencing Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco, pasteur.ma
1 shared publication - Fatna Bourjilat
Institut Pasteur du Maroc
1 shared publication
Latest Publications
- Open Access
- 1 January 2026
- Published by Wiley in International Journal of Microbiology
- Vol. 2026 (1) , 6271074
Global High‐Risk Escherichia coli Clones in Moroccan Aquatic Settings: Genomic Evidence of Environmental Dissemination
Background: Globally disseminated high‐risk Escherichia coli ( E. coli ) clones are major drivers of multidrug resistance (MDR) and severe clinical infections. Their presence in aquatic ecosystems represents a growing One Health concern, particularly in regions where wastewater management remains limited. Objective: This study aimed to investigate the environmental circulation and genomic characteristics of high‐risk E. coli in Moroccan aquatic environments. Methods: Water samples were collected between February and June 2024 from seven major rivers and three wastewater treatment plants (WWTPs) across eight Moroccan cities. A total of 22 E. coli isolates were recovered and analyzed by whole‐genome sequencing to determine their sequence types (STs), antimicrobial resistance genes, virulence factors, and plasmid replicon profiles. Results: Sixteen isolates originated from rivers (72.7%) and six from WWTPs (27.3%). Thirteen distinct STs were identified, dominated by the globally disseminated high‐risk clones ST44 ( n = 4; 18.2%), ST410 ( n = 4; 18.2%), and ST131 ( n = 3; 13.6%). The most frequent extended‐spectrum β ‐lactamase (ESBL) gene was bla CTX-M-15 ( n = 13; 59.1%). Carbapenemase genes were found in five isolates (22.7%), including bla NDM-5 ( n = 2; 9.1%), bla OXA-48 ( n = 1; 4.5%), bla OXA-181 ( n = 1; 4.5%), bla OXA-484 ( n = 2; 9.1%), and bla OXA-244 ( n = 1; 4.5%), whereas mcr-1.1 was detected in one isolate (4.5%). Plasmid profiling showed a predominance of IncF‐type replicons (IncFIB 81.8%, IncFII 77.3%, and IncFIA 68.2%), along with IncI (36.4%), IncX (13.6%), and IncHI (9.1%). Conclusion: This study provides the first genomic evidence of clinically relevant high‐risk E. coli clones and mobile resistance determinants circulating in Moroccan aquatic environments. These findings highlight the urgent need to strengthen integrated One Health surveillance to prevent environmental dissemination and reduce the public health impact of antimicrobial resistance.
- 1 January 2026
- Published by Wiley in International Journal of Microbiology
- Vol. 2026 (1) , 6271074
Open AccessGlobal High‐Risk Escherichia coli Clones in Moroccan Aquatic Settings: Genomic Evidence of Environmental Dissemination
Background: Globally disseminated high‐risk Escherichia coli ( E. coli ) clones are major drivers of multidrug resistance (MDR) and severe clinical infections. Their presence in aquatic ecosystems represents a growing One Health concern, particularly in regions where wastewater management remains limited. Objective: This study aimed to investigate the environmental circulation and genomic characteristics of high‐risk E. coli in Moroccan aquatic environments. Methods: Water samples were collected between February and June 2024 from seven major rivers and three wastewater treatment plants (WWTPs) across eight Moroccan cities. A total of 22 E. coli isolates were recovered and analyzed by whole‐genome sequencing to determine their sequence types (STs), antimicrobial resistance genes, virulence factors, and plasmid replicon profiles. Results: Sixteen isolates originated from rivers (72.7%) and six from WWTPs (27.3%). Thirteen distinct STs were identified, dominated by the globally disseminated high‐risk clones ST44 ( n = 4; 18.2%), ST410 ( n = 4; 18.2%), and ST131 ( n = 3; 13.6%). The most frequent extended‐spectrum β ‐lactamase (ESBL) gene was bla CTX-M-15 ( n = 13; 59.1%). Carbapenemase genes were found in five isolates (22.7%), including bla NDM-5 ( n = 2; 9.1%), bla OXA-48 ( n = 1; 4.5%), bla OXA-181 ( n = 1; 4.5%), bla OXA-484 ( n = 2; 9.1%), and bla OXA-244 ( n = 1; 4.5%), whereas mcr-1.1 was detected in one isolate (4.5%). Plasmid profiling showed a predominance of IncF‐type replicons (IncFIB 81.8%, IncFII 77.3%, and IncFIA 68.2%), along with IncI (36.4%), IncX (13.6%), and IncHI (9.1%). Conclusion: This study provides the first genomic evidence of clinically relevant high‐risk E. coli clones and mobile resistance determinants circulating in Moroccan aquatic environments. These findings highlight the urgent need to strengthen integrated One Health surveillance to prevent environmental dissemination and reduce the public health impact of antimicrobial resistance.
- Open Access
- 21 May 2024
- Published by AOSIS in Journal of Public Health in Africa
- Vol. 15 (1) , 3
First report of blaOXA-48 producing Klebsiella pneumoniae isolates from wastewater in Morocco
The Journal of Public Health in Africa (JPHiA) is a peer-reviewed, academic journal that focuses on health issues in the African continent. The journal editors seek high quality original articles on public health related issues, reviews, comments and more. The aim of the journal is to move public health discourse from the background to the forefront. The success of Africa’s struggle against disease depends on public health approaches.
- 21 May 2024
- Published by AOSIS in Journal of Public Health in Africa
- Vol. 15 (1) , 3
Open AccessFirst report of blaOXA-48 producing Klebsiella pneumoniae isolates from wastewater in Morocco
The Journal of Public Health in Africa (JPHiA) is a peer-reviewed, academic journal that focuses on health issues in the African continent. The journal editors seek high quality original articles on public health related issues, reviews, comments and more. The aim of the journal is to move public health discourse from the background to the forefront. The success of Africa’s struggle against disease depends on public health approaches.