Guilherme Henrique
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Guilherme Henrique has a total of 14 co-authors. Here are the top co-authors by number of shared publications:
- Bruna Monteiro Alves
Laboratório de Endocrinologia Molecular e Translacional (LEMT), Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo 04039-032, SP, Brazil
1 shared publication - Caroline Serrano-Nascimento
Department of Biological Sciences, Laboratory of Thyroid Physiology and Pathophysiology (LaFFT), Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF), Federal University of São Paulo (UNIFESP), Rua Professor Arthur Riedel, 275, 09972-270, SP, Brazil; Department of Medicine, Laboratory of Molecular and Translational Endocrinology (LEMT), Federal University of São Paulo (UNIFESP), Rua Pedro de Toledo, 669 - 11° andar - L11E, 04039-032, SP, Brazil
1 shared publication - Evelyn Franciny Cardoso Tavares
Laboratório de Endocrinologia Molecular e Translacional (LEMT), Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo 04039-032, SP, Brazil
1 shared publication - Gisele Giannocco
Molecular and Translational Endocrinology Laboratory, Thyroid Disease Center, Division of Endocrinology, Department of Medicine, Universidade Federal de São Paulo (UNIFESP), São Paulo 04039-032, SP, Brazil
1 shared publication - João Anthony Araújo Pinto
Laboratório de Endocrinologia Molecular e Translacional (LEMT), Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo 04039-032, SP, Brazil
1 shared publication - Kelly Cristina de Oliveira
Laboratório de Endocrinologia Molecular e Translacional (LEMT), Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo 04039-032, SP, Brazil
1 shared publication
Latest Publications
- Open Access
- 19 September 2024
- Published by MDPI AG in Endocrines
- Vol. 5 (3) , 430-453
Thyroid under Attack: The Adverse Impact of Plasticizers, Pesticides, and PFASs on Thyroid Function
Endocrine-disrupting chemicals (EDCs) are synthetic or natural compounds that interfere with the endocrine system, inducing harmful effects on organisms depending on the dose and period of exposure. Numerous studies have identified concerning amounts of EDCs in environmental and human samples. The thyroid gland is essential for thyroid hormone production and controls several body functions. Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years. Some studies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products. Although the impact of human exposure to these EDCs is controversial, numerous epidemiological, in vivo, and in vitro studies have indicated their harmful effects on thyroid function. Given the critical role of thyroid function and hormone production in growth, metabolism, and development, this review summarizes the consequences of exposure to thyroid disruptors for human health.
- 19 September 2024
- Published by MDPI AG in Endocrines
- Vol. 5 (3) , 430-453
Open AccessThyroid under Attack: The Adverse Impact of Plasticizers, Pesticides, and PFASs on Thyroid Function
Endocrine-disrupting chemicals (EDCs) are synthetic or natural compounds that interfere with the endocrine system, inducing harmful effects on organisms depending on the dose and period of exposure. Numerous studies have identified concerning amounts of EDCs in environmental and human samples. The thyroid gland is essential for thyroid hormone production and controls several body functions. Several EDCs have been classified as thyroid disruptors, impairing thyroid hormone production, synthesis, metabolism, transport, and/or actions. Notably, thyroid disorders are the second most prevalent endocrine disease worldwide, with incidence increasing significantly in recent years. Some studies have correlated this rise in thyroid dysfunctions and cancers with increased exposure to EDCs. Although many EDCs are linked to thyroid dysfunction, this review focuses on the deleterious effects of plasticizers, organochlorine pesticides, and per- and poly-fluoroalkyl substances on thyroid function. These contaminants are commonly found in food, water, and everyday products. Although the impact of human exposure to these EDCs is controversial, numerous epidemiological, in vivo, and in vitro studies have indicated their harmful effects on thyroid function. Given the critical role of thyroid function and hormone production in growth, metabolism, and development, this review summarizes the consequences of exposure to thyroid disruptors for human health.