Kyung Mi Kim
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Kyung Mi Kim has a total of 5 co-authors. Here are the top co-authors by number of shared publications:
- Jee Min Kim
Department of BioNano Technology, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam 13120, Gyeonggi-do, Republic of Korea
1 shared publication - Jin Woo Park
BioActs BM&S Co., Ltd., 80-59, Golden Root-Ro, Juchon-Myeon, Gimhae 50969, Gyeongsangnam-do, Republic of Korea
1 shared publication - Moon Il Kim
Environmental Microbial and Food Safety Laboratory, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, U.S.A.
1 shared publication - Phuong Thy Nguyen
Department of BioNano Technology, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam 13120, Republic of Korea
1 shared publication - Seung Hoo Song
Department of BioNano Technology, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam 13120, Gyeonggi-do, Republic of Korea
1 shared publication
Latest Publications
- Open Access
- 20 September 2024
- Published by MDPI AG in Chemosensors
- Vol. 12 (9) , 193
Chemiluminescence Immunoassay for Sensitive Detection of C-reactive Protein Using Graphene Oxide–Gold Nanoparticle–Luminol Hybrids as Enhanced Luminogenic Molecules
This study presents the development of luminol and gold nanoparticle co-functionalized graphene oxide (GO-AuNPs-L) hybrids as enhanced luminogenic signaling molecules in the chemiluminescence immunoassay (CLIA) for detecting C-reactive protein (CRP), a key biomarker of inflammation and cardiovascular diseases. When compared to free luminol, the GO-AuNPs-L hybrids significantly increased and prolonged the CL signal based on their synergistic enhancement in electron transfer during CL production. Based on the performance, the hybrids were employed as signaling molecules in both well plate-based and lateral flow CLIA platforms, showing substantial improvements in signal intensity and sensitivity in CRP detection. These results highlight the potential of GO-AuNPs-L hybrids as versatile and highly sensitive luminogenic molecules for immunological CRP detection, offering promising applications in clinical laboratory settings as well as in point-of-care diagnostics.
- 20 September 2024
- Published by MDPI AG in Chemosensors
- Vol. 12 (9) , 193
Open AccessChemiluminescence Immunoassay for Sensitive Detection of C-reactive Protein Using Graphene Oxide–Gold Nanoparticle–Luminol Hybrids as Enhanced Luminogenic Molecules
This study presents the development of luminol and gold nanoparticle co-functionalized graphene oxide (GO-AuNPs-L) hybrids as enhanced luminogenic signaling molecules in the chemiluminescence immunoassay (CLIA) for detecting C-reactive protein (CRP), a key biomarker of inflammation and cardiovascular diseases. When compared to free luminol, the GO-AuNPs-L hybrids significantly increased and prolonged the CL signal based on their synergistic enhancement in electron transfer during CL production. Based on the performance, the hybrids were employed as signaling molecules in both well plate-based and lateral flow CLIA platforms, showing substantial improvements in signal intensity and sensitivity in CRP detection. These results highlight the potential of GO-AuNPs-L hybrids as versatile and highly sensitive luminogenic molecules for immunological CRP detection, offering promising applications in clinical laboratory settings as well as in point-of-care diagnostics.