Liuxia Lin
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Liuxia Lin has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Amei Huang
College of Life Science, Tarim University, Alaer 843300, China
1 shared publication - Chen Wei
College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang 524088, China
1 shared publication - Chunmei Du
College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, China
1 shared publication - Jian Ma
College of Coastal Agricultural Sciences, Guangdong Ocean University, Zhanjiang, China
1 shared publication - Mengsi Xu
Institute of Animal Husbandry and Veterinary Medicine, Xinjiang Academy of Agricultural and Reclamation Science, Shihezi 832000, China
1 shared publication - Qinghua Gao
College of Animal Science and Technology, Tarim University, Alar 843300, China
1 shared publication
Latest Publications
- Open Access
Behavioral Assessment Reveals GnRH Immunocastration as a Better Alternative to Surgical Castration
Castration is often employed in animal management for reproductive control. However, it is important to evaluate its impact on animal welfare. In this study, we developed rat models for both surgical (n = 6) and GnRH immunocastration (n = 6) to assess the effects of these castration methods on physiological and behavioral characteristics. The novel GnRH-based vaccine significantly increased serum GnRH antibody levels and drastically reduced testosterone, with the testes shrinking to one-fifth the size of those in the control group, thereby halting spermatogenesis at the secondary spermatocyte stage. Behavioral evaluations demonstrated that sexual behavior was significantly suppressed in both surgically and immunologically castrated groups compared to the control, confirming the effectiveness of both methods. However, psychological tests revealed significant signs of depression and social deficits in the surgically castrated group, whereas the behavior of the GnRH-immunocastrated group did not significantly differ from the control. Furthermore, no significant differences in learning and memory were observed among the three groups in the water maze test. Compared to surgical castration, GnRH immunocastration offers effective results and better animal welfare, providing a more humane alternative for livestock management.
Open AccessBehavioral Assessment Reveals GnRH Immunocastration as a Better Alternative to Surgical Castration
Castration is often employed in animal management for reproductive control. However, it is important to evaluate its impact on animal welfare. In this study, we developed rat models for both surgical (n = 6) and GnRH immunocastration (n = 6) to assess the effects of these castration methods on physiological and behavioral characteristics. The novel GnRH-based vaccine significantly increased serum GnRH antibody levels and drastically reduced testosterone, with the testes shrinking to one-fifth the size of those in the control group, thereby halting spermatogenesis at the secondary spermatocyte stage. Behavioral evaluations demonstrated that sexual behavior was significantly suppressed in both surgically and immunologically castrated groups compared to the control, confirming the effectiveness of both methods. However, psychological tests revealed significant signs of depression and social deficits in the surgically castrated group, whereas the behavior of the GnRH-immunocastrated group did not significantly differ from the control. Furthermore, no significant differences in learning and memory were observed among the three groups in the water maze test. Compared to surgical castration, GnRH immunocastration offers effective results and better animal welfare, providing a more humane alternative for livestock management.