Dae Hyeok An
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Dae Hyeok An has a total of 7 co-authors. Here are the top co-authors by number of shared publications:
- Hee Cheol Kang
Department of Materials Science and Engineering, Soongsil University, 369 Sangdo-Ro, Dongjak-Gu, Seoul 06978, Republic of Korea
1 shared publication - Hojin Lee
Soongsil University
1 shared publication - Jae Hyun Jeong
Department of Chemical Engineering, Soongsil University, Seoul 06978, Republic of Korea
1 shared publication - Jae Woo Chung
Department of Materials Science and Engineering, Soongsil University, 369 Sangdo-Ro, Dongjak-Gu, Seoul 06978, Republic of Korea
1 shared publication - Jun Woo Lim
Department of Chemical Engineering, Soongsil University, 369 Sangdo-ro, Dongjak-gu, Seoul 06978, Republic of Korea
1 shared publication - Junho Kim
Department of Convergence IT Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea
1 shared publication
Latest Publications
- Open Access
- 28 October 2024
- Published by MDPI AG in Micromachines
- Vol. 15 (11) , 1309
Fabrication and Characterization of Biocompatible Multilayered Elastomer Hybrid with Enhanced Water Permeation Resistance for Packaging of Implantable Biomedical Devices
This study presents the synthesis and characterization of hexadecyl-modified SiO2 (HD-SiO2) nanoparticles and their application in the fabrication of a multilayered elastomer hybrid sheet to enhance water resistance in implantable biomedical devices. The surface modification of SiO2 nanoparticles was confirmed via FT-IR and TGA analyses, showing the successful grafting of hydrophobic hexadecyl groups. FE-SEM and DLS analyses revealed spherical HD-SiO2 nanoparticles with an average size of 360 nm. A multilayered elastomer hybrid sheet, consisting of a PDMS-based circuit-protecting body, a water resistance layer of HD-SiO2, a planarization layer, and a biocompatible layer of polydopamine, was fabricated and characterized. The water resistance layer exhibited superhydrophobic properties, with a water contact angle of 154.7° and a 27% reduction in water vapor transmission rate (WVTR) compared to the circuit-protecting body alone. The device packaged with both the circuit-protecting body and water resistance layer demonstrated a tenfold increase in operational lifespan in water medium compared to the device without the water resistance layer. Cytotoxicity and cell proliferation tests on human dermal fibroblast cells (HDFn) confirmed the biocompatibility of the multilayered sheet, with no significant cytotoxicity observed over 48 h.
- 28 October 2024
- Published by MDPI AG in Micromachines
- Vol. 15 (11) , 1309
Open AccessFabrication and Characterization of Biocompatible Multilayered Elastomer Hybrid with Enhanced Water Permeation Resistance for Packaging of Implantable Biomedical Devices
This study presents the synthesis and characterization of hexadecyl-modified SiO2 (HD-SiO2) nanoparticles and their application in the fabrication of a multilayered elastomer hybrid sheet to enhance water resistance in implantable biomedical devices. The surface modification of SiO2 nanoparticles was confirmed via FT-IR and TGA analyses, showing the successful grafting of hydrophobic hexadecyl groups. FE-SEM and DLS analyses revealed spherical HD-SiO2 nanoparticles with an average size of 360 nm. A multilayered elastomer hybrid sheet, consisting of a PDMS-based circuit-protecting body, a water resistance layer of HD-SiO2, a planarization layer, and a biocompatible layer of polydopamine, was fabricated and characterized. The water resistance layer exhibited superhydrophobic properties, with a water contact angle of 154.7° and a 27% reduction in water vapor transmission rate (WVTR) compared to the circuit-protecting body alone. The device packaged with both the circuit-protecting body and water resistance layer demonstrated a tenfold increase in operational lifespan in water medium compared to the device without the water resistance layer. Cytotoxicity and cell proliferation tests on human dermal fibroblast cells (HDFn) confirmed the biocompatibility of the multilayered sheet, with no significant cytotoxicity observed over 48 h.