Karessa Manning
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Karessa Manning has a total of 20 co-authors. Here are the top co-authors by number of shared publications:
- Fredrick Dolislager
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
14 shared publications Usdoe
14 shared publications- Debra Stewart
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
12 shared publications Katie Noto
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
12 shared publications- Janou Milligan
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
8 shared publications - Anthony Armstrong
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
5 shared publications
Latest Publications
- Open Access
- 1 September 2025
- Published by Office of Scientific and Technical Information (OSTI)
Technical Background and Validation Report on the Residential Water Inhalation Risk Calculator Presented in the Risk Assessment Information System
Indoor air quality (IAQ) is critical for human health. Poor IAQ is linked to respiratory issues, cardiovascular diseases, and cancer. Indoor pollutants are emitted by typical household items such as cleaning products, personal care items, building materials, and tap water - an understudied volatile organic compound (VOC) source. This document presents the Residential Water Inhalation Risk Calculator (RWIRC), which estimates daily VOC exposure concentrations from various household water uses, such as showering and dishwashing, to assess exposure risks for the most vulnerable occupant. Integrated into the Risk Assessment Information System (RAIS) and sponsored by the US Department of Energy (DOE), the calculator divides a house into three compartments: shower, bathroom, and other spaces, accounting for daily water usage patterns and calculating VOC concentrations. Exposure data generated using the calculator can assist health assessors in estimating excess lifetime cancer risk (ELCR) and hazard index (HI) from VOC inhalation. Unlike traditional exposure models that utilize Andelman’s constant, the RWIRC continuously assesses variability in VOC concentrations and environmental conditions using differential equations to track VOC concentrations and air exchange between compartments. The calculator also provides unique volatilization fractions for each chemical and appliance, enhancing accuracy of the exposure concentration estimation. The RWIRC is accessible online and allows users to customize parameters (i.e., number of bathrooms, water temperature, and exhaust fan conditions) and input VOC characteristics (i.e., tap water and ambient air concentrations). This document provides a step-by-step guide on implementing the calculator. It also provides comparisons with the ATSDR-SHOWER calculator, using eight VOCs with varying physicochemical properties to reveal differences in algorithms and output concentrations. Simulations also assess how bathroom door positions and exhaust fan usage affect VOC exposure. The calculator results can enhance EPA risk screening levels for inhalation exposure to VOCs from tap water, offering a sophisticated tool for assessing inhalation risks and improving public health protection.
- 1 September 2025
- Published by Office of Scientific and Technical Information (OSTI)
Open AccessTechnical Background and Validation Report on the Residential Water Inhalation Risk Calculator Presented in the Risk Assessment Information System
Indoor air quality (IAQ) is critical for human health. Poor IAQ is linked to respiratory issues, cardiovascular diseases, and cancer. Indoor pollutants are emitted by typical household items such as cleaning products, personal care items, building materials, and tap water - an understudied volatile organic compound (VOC) source. This document presents the Residential Water Inhalation Risk Calculator (RWIRC), which estimates daily VOC exposure concentrations from various household water uses, such as showering and dishwashing, to assess exposure risks for the most vulnerable occupant. Integrated into the Risk Assessment Information System (RAIS) and sponsored by the US Department of Energy (DOE), the calculator divides a house into three compartments: shower, bathroom, and other spaces, accounting for daily water usage patterns and calculating VOC concentrations. Exposure data generated using the calculator can assist health assessors in estimating excess lifetime cancer risk (ELCR) and hazard index (HI) from VOC inhalation. Unlike traditional exposure models that utilize Andelman’s constant, the RWIRC continuously assesses variability in VOC concentrations and environmental conditions using differential equations to track VOC concentrations and air exchange between compartments. The calculator also provides unique volatilization fractions for each chemical and appliance, enhancing accuracy of the exposure concentration estimation. The RWIRC is accessible online and allows users to customize parameters (i.e., number of bathrooms, water temperature, and exhaust fan conditions) and input VOC characteristics (i.e., tap water and ambient air concentrations). This document provides a step-by-step guide on implementing the calculator. It also provides comparisons with the ATSDR-SHOWER calculator, using eight VOCs with varying physicochemical properties to reveal differences in algorithms and output concentrations. Simulations also assess how bathroom door positions and exhaust fan usage affect VOC exposure. The calculator results can enhance EPA risk screening levels for inhalation exposure to VOCs from tap water, offering a sophisticated tool for assessing inhalation risks and improving public health protection.
- Open Access
- 1 October 2024
- Published by Office of Scientific and Technical Information (OSTI)
Identification and Reclassification of Mutagenic Chemicals for Improved Human Health Screening Levels
The U.S. Department of Energy's Office of Scientific and Technical Information
- 1 October 2024
- Published by Office of Scientific and Technical Information (OSTI)
Open AccessIdentification and Reclassification of Mutagenic Chemicals for Improved Human Health Screening Levels
The U.S. Department of Energy's Office of Scientific and Technical Information