Apoorva Mishra

Objective: This review aims to provide a comprehensive overview of omics fields – including genomics, epigenomics, transcriptomics, proteomics, metabolomics, single- -cell multiomics, microbiomics, and radiomics – and to highlight the significance of integrating these datasets to tackle complex biological questions in systems biology and precision medicine.Methods: The review analyzes current literature across various omics domains, focusing on their individual contributions to cellular functions and their integration challenges. It discusses successful integration examples and addresses issues like data heterogeneity across databases.Results: Omics integration significantly enhances our understanding of biological systems, with each field offering unique insights. Despite challenges with data inconsistencies, successful cases show the potential of integrated omics in advancing personalized medicine, drug discovery, and disease research.Conclusions: Advancing omics integration is essential for breakthroughs in personalized medicine and complex disease studies. Interdisciplinary collaboration will be crucial to overcoming data challenges and realizing the full potential of omics in biomedical advancements.

Surveillance work was initiated to study the presence of highly infectious diseases like Ebola-Reston, Marburg, Nipah and other possible viruses that are known to be found in the bat species and responsible for causing diseases in humans. A novel adenovirus was isolated from a common species of fruit bat (Rousettus leschenaultii) captured in Maharashtra State, India. Partial sequence analysis of the DNA polymerase gene shows this isolate to be a newly recognized member of the genus Mastadenovirus (family Adenoviridae), approximately 20% divergent at the nucleotide level from Japanese BatAdV, its closest known relative.