Edith Schlagenhauf
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Edith Schlagenhauf has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Alexandros Georgios Sotiropoulos
Centre for Crop Health and School of Science, Engineering and Digital Technologies, University of Southern Queensland, Toowoomba, Australia
1 shared publication - Alina Pfammatter
University of Zürich
1 shared publication - Aline Herger
Department of Plant and Microbial Biology, University of Zürich, Zürich, Switzerland
1 shared publication - Carlotta Marie Wehrkamp
University of Zürich
1 shared publication - Johannes Graf
Department of Plant and Microbial Biology, University of Zürich, Zürich, Switzerland
1 shared publication Jonatan Isaksson
University of Zürich
1 shared publication
Latest Publications
- Open Access
A reference metagenome sequence of the lichen Cladonia rangiformis
Summary: ● Lichens are an ancient symbiosis comprising the thalli of lichen-forming fungi, their photoautotrophic partners and their microbiome. So far, they were poorly studied at the genome sequence level. Here, we present a reference metagenome for the holobiont of Cladonia rangiformis . ● Using long read sequences from an entire symbiotic complex, plus short read libraries from 28 additional diverse European lichen samples, we were able to separate genome sequences of 20 individual species. ● We constructed chromosome-scale assemblies of the C. rangiformis fungus and its trebouxioid green algal photobiont Asterochloris mediterranea . The genome of the fungus comprises ∼22% transposable elements and is highly compartmentalized into genic regions and large TE-derived segments which show extensive signatures of repeat-induced point mutations (RIP). We found that A. mediterranea centromeres are predominantly derived from two interacting retrotransposon families. We also identified strong candidates for genes that were horizontally transferred from bacteria to both alga and fungus. Furthermore, we isolated 18 near-complete bacterial genomes, of which 13 are enriched in the lichen compared to surrounding soil. ● Our study revealed that the thalli of C. rangiformis have a highly complex microbiome, comprising a mix of species that may include opportunists, ecologically obligate symbionts and possibly even lichen-beneficial bacteria.
Open AccessA reference metagenome sequence of the lichen Cladonia rangiformis
Summary: ● Lichens are an ancient symbiosis comprising the thalli of lichen-forming fungi, their photoautotrophic partners and their microbiome. So far, they were poorly studied at the genome sequence level. Here, we present a reference metagenome for the holobiont of Cladonia rangiformis . ● Using long read sequences from an entire symbiotic complex, plus short read libraries from 28 additional diverse European lichen samples, we were able to separate genome sequences of 20 individual species. ● We constructed chromosome-scale assemblies of the C. rangiformis fungus and its trebouxioid green algal photobiont Asterochloris mediterranea . The genome of the fungus comprises ∼22% transposable elements and is highly compartmentalized into genic regions and large TE-derived segments which show extensive signatures of repeat-induced point mutations (RIP). We found that A. mediterranea centromeres are predominantly derived from two interacting retrotransposon families. We also identified strong candidates for genes that were horizontally transferred from bacteria to both alga and fungus. Furthermore, we isolated 18 near-complete bacterial genomes, of which 13 are enriched in the lichen compared to surrounding soil. ● Our study revealed that the thalli of C. rangiformis have a highly complex microbiome, comprising a mix of species that may include opportunists, ecologically obligate symbionts and possibly even lichen-beneficial bacteria.