Aditya Agita Sembiring
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Aditya Agita Sembiring has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Amiliana Mardiani Soesanto
Division of Non‐Invasive Diagnostic and Cardiovascular Imaging, Department of Cardiology and Vascular Medicine, Faculty of Medicine Universitas Indonesia, National Cardiovascular Center Harapan Kita Jakarta Indonesia
1 shared publication - Amin Al-Ahmad
Texas Cardiac Arrhythmia Research Foundation, Austin, Texas, USA
1 shared publication - Dicky Armein Hanafy
National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
1 shared publication - Dony Yugo Hermanto
National Cardiovascular Center Harapan Kita, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia
1 shared publication - Emir Yonas
Faculty of Medicine, Universitas YARSI, Jakarta, Indonesia
1 shared publication - Muhammad Rizky Felani
Cardiologist, Department of Cardiology and Vascular, Mohammad Hoesin General Hospital/Department of Cardiology and Vascular, Hermina Hospital, Palembang, Indonesia
1 shared publication
Latest Publications
- Open Access
- 15 January 2025
- Published by Springer Nature in Journal of Interventional Cardiac Electrophysiology
- Vol. 68 (6) , 1189-1196
Right ventricular subclinical dysfunction in high-burden idiopathic outflow tract premature ventricular contraction population
Background The relationship between premature ventricular contractions (PVC) and right ventricular (RV) function is not widely known. Left ventricular (LV) dysfunction due to PVC is known as PVC-induced cardiomyopathy (PIC) and suppressing the PVC substrate would improve LV function. The effect of PVC ablation on changes in RV function in patients with subtle RV subclinical dysfunction remains unknown. Objective Understanding the alterations in RV function parameters after PVC ablation. Method Basic and speckle-tracking echocardiography has been performed on 42 individuals with symptomatic idiopathic outflow tract PVC before and 1 month after a successful ablation. Result At the baseline of the study, there were 26 patients with RV subclinical dysfunction and 16 patients without RV dysfunction. Patients with RV subclinical dysfunction exhibited significantly higher PVC burden and QRS complex duration than those with normal RV function (p < 0.05). A PVC burden ≥ 21% (OR 9.11, 1.54–53.87, p = 0.015) and a QRS complex duration ≥ 138 ms (OR 5.74, 1.07–30.90, p = 0.042) were independently associated with RV subclinical dysfunction. In both groups, measurements of RV subclinical function before and after ablation, specifically by free wall longitudinal strain (FWLS) and global longitudinal strain (GLS), demonstrated significant changes. These improvements were more pronounced in the group with RV dysfunction (FWLS 9.7 ± 4.0, p < 0.001; GLS 7.5 ± 4.2, p < 0.001). Lower initial FWLS and GLS before ablation emerged as significant parameters in the multivariate analysis for the improvement of RV function post-ablation. Conclusion Patients with RV subclinical dysfunction had higher PVC burden and wider QRS duration. Patients with idiopathic outflow tract PVC with RV subclinical dysfunction may experience improvements in RV function after successful PVC ablation. Graphical Abstract
- 15 January 2025
- Published by Springer Nature in Journal of Interventional Cardiac Electrophysiology
- Vol. 68 (6) , 1189-1196
Open AccessRight ventricular subclinical dysfunction in high-burden idiopathic outflow tract premature ventricular contraction population
Background The relationship between premature ventricular contractions (PVC) and right ventricular (RV) function is not widely known. Left ventricular (LV) dysfunction due to PVC is known as PVC-induced cardiomyopathy (PIC) and suppressing the PVC substrate would improve LV function. The effect of PVC ablation on changes in RV function in patients with subtle RV subclinical dysfunction remains unknown. Objective Understanding the alterations in RV function parameters after PVC ablation. Method Basic and speckle-tracking echocardiography has been performed on 42 individuals with symptomatic idiopathic outflow tract PVC before and 1 month after a successful ablation. Result At the baseline of the study, there were 26 patients with RV subclinical dysfunction and 16 patients without RV dysfunction. Patients with RV subclinical dysfunction exhibited significantly higher PVC burden and QRS complex duration than those with normal RV function (p < 0.05). A PVC burden ≥ 21% (OR 9.11, 1.54–53.87, p = 0.015) and a QRS complex duration ≥ 138 ms (OR 5.74, 1.07–30.90, p = 0.042) were independently associated with RV subclinical dysfunction. In both groups, measurements of RV subclinical function before and after ablation, specifically by free wall longitudinal strain (FWLS) and global longitudinal strain (GLS), demonstrated significant changes. These improvements were more pronounced in the group with RV dysfunction (FWLS 9.7 ± 4.0, p < 0.001; GLS 7.5 ± 4.2, p < 0.001). Lower initial FWLS and GLS before ablation emerged as significant parameters in the multivariate analysis for the improvement of RV function post-ablation. Conclusion Patients with RV subclinical dysfunction had higher PVC burden and wider QRS duration. Patients with idiopathic outflow tract PVC with RV subclinical dysfunction may experience improvements in RV function after successful PVC ablation. Graphical Abstract