Wanying Geng

As a non-invasive, quantitative, and objective evaluation method, the analysis of bowel sounds has shown significant potential in clinical practice. In recent years, with the continuous advancement of signal processing techniques and analysis methods, research on bowel sounds has made significant progress. In this review, we discuss the main clinical applications of bowel sounds and summarize the commonly used analysis methods for bowel sounds at present. It is necessary to explore more comprehensive and effective signal processing technologies and methods in the future, and also establish a well-organized bowel sound database and scientific classification standards. This will promote better application of bowel sounds in clinical practice.

Non-alcoholic fatty liver disease (NAFLD) and its advanced form, non-alcoholic steatohepatitis (NASH), are the leading causes of chronic liver disease globally. They are driven by complex mechanisms where inflammation plays a pivotal role in disease progression. Current therapies, including lifestyle changes and pharmacological agents, are limited in efficacy, particularly in addressing the advanced stages of the disease. Emerging approaches targeting inflammation, metabolic dysfunction, and fibrosis offer promising new directions, though challenges such as treatment complexity and heterogeneity persist. This review concludes the main therapeutic targets and approaches to manage inflammation currently and emphasizes the critical need for future drug development and combination therapy for NAFLD/NASH management.