Tasneem Ali Odat
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Tasneem Ali Odat has a total of 14 co-authors. Here are the top co-authors by number of shared publications:
- Alaa AbuAwad
Department of Pharmaceutical Sciences and Pharmaceutics, Faculty of Pharmacy, Applied Science Private University (ASU), Amman 11937, Jordan
2 shared publications - Areen Alshweiat
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, The Hashemite University, Zarqa 13133, Jordan
2 shared publications - Irina Smirnova
Hamburg University of Technology
2 shared publications - Mohammad A. A. AL Najjar
Faculty of Pharmacy, Applied Science Private University, Amman, Jordan
2 shared publications - Raghad Garafat
Institute of Nanotechnology, Jordan University of Science and Technology, Irbid 22110, Jordan
2 shared publications - Razan Altarabeen
Institute of Thermal Separation Processes, Hamburg University of Technology, Eißendorfer Straße 38, 21073 Hamburg, Germany
2 shared publications
Latest Publications
- Open Access
Preparation and Characterization of Copper-Crosslinked Alginate–Hyaluronic Acid Aerogels as Potential Wound Dressing Materials with Enhanced Antibacterial Properties
The development of advanced wound dressing materials with enhanced antibacterial properties is critical for improving patient outcomes and reducing infection risks. This study introduces a novel bio-based aerogel composed of copper-crosslinked alginate and hyaluronic acid, synthesized using supercritical gel drying techniques. Alginate and hyaluronic acid polymers are widely used in the pharmaceutical and medical industries because of their nontoxicity, biodegradability, and biocompatibility. This study aimed to create an aerogel that could be used as a potential wound dressing material by crosslinking hyaluronic acid and alginate with copper. The bio-based aerogel was prepared by ionic gelation and supercritical gel drying. The prepared materials were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), BET surface area analysis, and energy-dispersive X-ray fluorescence (XRF). Moreover, the aerogel wound dressing properties were evaluated in terms of fluid uptake and antibacterial activity against S. aureus and E. coli. The physicochemical characterization of the prepared aerogels revealed their unique structural and morphological features, which are influenced by copper ion concentration and crosslinking time. Regarding their wound dressing evaluation, both aerogel and hydrogel were found to have antibacterial properties when tested on S. aureus with inhibition zones of (36 mm, 23 mm) and E. coli (31.6 mm, 21 mm) for hydrogel and aerogel, respectively. Also, excellent fluid uptake was found to reach up to 743%. These findings underscore the potential of copper-crosslinked alginate–hyaluronic acid aerogels as innovative wound dressing materials that combine superior antibacterial efficacy with excellent fluid management, paving the way for improved wound healing solutions.
Open AccessPreparation and Characterization of Copper-Crosslinked Alginate–Hyaluronic Acid Aerogels as Potential Wound Dressing Materials with Enhanced Antibacterial Properties
The development of advanced wound dressing materials with enhanced antibacterial properties is critical for improving patient outcomes and reducing infection risks. This study introduces a novel bio-based aerogel composed of copper-crosslinked alginate and hyaluronic acid, synthesized using supercritical gel drying techniques. Alginate and hyaluronic acid polymers are widely used in the pharmaceutical and medical industries because of their nontoxicity, biodegradability, and biocompatibility. This study aimed to create an aerogel that could be used as a potential wound dressing material by crosslinking hyaluronic acid and alginate with copper. The bio-based aerogel was prepared by ionic gelation and supercritical gel drying. The prepared materials were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), BET surface area analysis, and energy-dispersive X-ray fluorescence (XRF). Moreover, the aerogel wound dressing properties were evaluated in terms of fluid uptake and antibacterial activity against S. aureus and E. coli. The physicochemical characterization of the prepared aerogels revealed their unique structural and morphological features, which are influenced by copper ion concentration and crosslinking time. Regarding their wound dressing evaluation, both aerogel and hydrogel were found to have antibacterial properties when tested on S. aureus with inhibition zones of (36 mm, 23 mm) and E. coli (31.6 mm, 21 mm) for hydrogel and aerogel, respectively. Also, excellent fluid uptake was found to reach up to 743%. These findings underscore the potential of copper-crosslinked alginate–hyaluronic acid aerogels as innovative wound dressing materials that combine superior antibacterial efficacy with excellent fluid management, paving the way for improved wound healing solutions.
- Open Access
Investigation of the Antibacterial Activity of ZnO-Loaded Alginate/Hyaluronic Acid Aerogels for Wound Dressing Applications
The prevalence of bacterial infections in wounds is a significant challenge to successful wound healing. This study investigates the antibacterial effect of hyaluronic acid and alginate aerogel loaded with zinc oxide nanoparticles as a potential dressing for wound healing. The aerogel composite was synthesized via supercritical gel drying and characterized by scanning electron microscope, Fourier transform infrared spectroscopy, and nitrogen porosimetry. The absorptivity of the prepared aerogel was evaluated, as well as the antibacterial activity, which was evaluated against common wound pathogens, including Staphylococcus aureus and Escherichia coli, using the agar diffusion method. The results show the effective antibacterial properties of the prepared hydrogel and aerogel. Furthermore, the results show water absorption ability of 5791 and 1585% for loaded and unloaded aerogels, respectively. The ZnO released from the aerogel exhibited a rapid release followed by a slow and sustained release. These findings highlight the potential of aerogels based on hyaluronic acid and alginate and loaded with zinc oxide nanoparticles as an innovative antibacterial wound dressing material, which is expected to improve wound healing and reduce the risk of bacterial infections.
Open AccessInvestigation of the Antibacterial Activity of ZnO-Loaded Alginate/Hyaluronic Acid Aerogels for Wound Dressing Applications
The prevalence of bacterial infections in wounds is a significant challenge to successful wound healing. This study investigates the antibacterial effect of hyaluronic acid and alginate aerogel loaded with zinc oxide nanoparticles as a potential dressing for wound healing. The aerogel composite was synthesized via supercritical gel drying and characterized by scanning electron microscope, Fourier transform infrared spectroscopy, and nitrogen porosimetry. The absorptivity of the prepared aerogel was evaluated, as well as the antibacterial activity, which was evaluated against common wound pathogens, including Staphylococcus aureus and Escherichia coli, using the agar diffusion method. The results show the effective antibacterial properties of the prepared hydrogel and aerogel. Furthermore, the results show water absorption ability of 5791 and 1585% for loaded and unloaded aerogels, respectively. The ZnO released from the aerogel exhibited a rapid release followed by a slow and sustained release. These findings highlight the potential of aerogels based on hyaluronic acid and alginate and loaded with zinc oxide nanoparticles as an innovative antibacterial wound dressing material, which is expected to improve wound healing and reduce the risk of bacterial infections.