MAMercy Egrina Adiniko

Mercy Egrina Adiniko

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Mercy Egrina Adiniko has a total of 21 co-authors. Here are the top co-authors by number of shared publications:

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    Detection and molecular characterization of dengue among patients suspected of having malaria in Timika, Central Papua, Indonesia

    by Leily Trianty, Bunga Rana, Mercy Egrina Adiniko, Marsha Sinditia Santoso, Agatha Mia Puspitasari, Ristya Amalia, Pak Prayoga, Jeanne Rini Poespoprodjo, Enny Kenangalem, Dionisius Denis, et al.

    Background: Dengue and malaria are major public health problems in Indonesia. Dengue is hyperendemic nationwide, while malaria remains endemic in specific regions, especially in eastern Indonesia. Timika in Central Papua province is a highly malaria-endemic area; however, this city is historically known as a low endemic area for dengue. With the increasing incidence of dengue in Papua, this study aimed to assess dengue prevalence, possible co-infection and to molecularly characterize the dengue virus (DENV) in patients suspected of having malaria. Methods: Archived samples of patients suspected of having malaria were screened for dengue using RT-PCR. Dengue serological and antigen detection was performed and whole genome sequencing was employed to determine the genetic characteristics of viruses. Detection of other arboviruses was also performed. Results: Among 119 patients, 30 (25.2%) were positive for dengue. Most samples (n=29) were infected by DENV-3, while one was positive for DENV-2. Dengue and malaria co-infections were found in six patients. Phylogenetic analysis classified DENV-2 as the Cosmopolitan genotype that is closely related to strains from the Indonesian city of Makassar, while DENV-3 was classified as Genotype I, which is closely related to a strain from Singapore. Conclusions: Dengue significantly contributes to febrile illness among patients suspected of having malaria in Timika, Central Papua. Virus importation from surrounding regions is likely to contribute to the dispersion of DENV into eastern parts of Indonesia. Our findings reveal the underestimation of this viral disease in a highly malaria-endemic area.

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    Sensitivity and Specificity of an All-in-one Cartridge-based Dengue Real-time Reverse Transcription-PCR for Point-of-care Detection and Serotyping of Dengue Virus in Samples from Indonesian Patients

    by Marsha S. Santoso, Eggi Arguni, Bunga Rana, Mercy E. Adiniko, Dionisius Denis, Endah Supriyati, Citra Indriani, Leily Trianty, Riris Andono Ahmad, Rintis Noviyanti, et al.

    Marsha S. Santoso, M.D, M.I.P.H., Eggi Arguni, M.D, Ph.D., Bunga Rana, M.Sc., Mercy E. Adiniko, M.Sc., Dionisius Denis, M.Sc., Endah Supriyati, M.Sc., Citra Indriani, M.D, M.P.H., Leily Trianty, Ph.D., Riris Andono Ahmad, M.D, Ph.D., Rintis Noviyanti, Ph.D., and R. Tedjo Sasmono, Ph.D.. Ann Lab Med -0001;0:. https://doi.org/10.3343/alm.2024.0558

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