Miquel Sendra
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Miquel Sendra has a total of 10 co-authors. Here are the top co-authors by number of shared publications:
- Miguel Torres
Affiliations Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain, Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain
2 shared publications Jorge Mañes
Cardiovascular Regeneration Program, Centro Nacional de Investigaciones Cardiovasculares (CNIC)
1 shared publicationJorge N. Domínguez
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), 28029 Madrid, Spain; Department of Experimental Biology, Faculty of Health Sciences University of Jaén, Jaén 23071, Spain
1 shared publication- Jorge Nicolás Dominguez
Department of Experimental Biology, Faculty of Experimental Sciences, University of Jaén
1 shared publication Juan de Dios Hourcade
Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain
1 shared publicationKatie McDole
MRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK
1 shared publication
Latest Publications
- Open Access
- 27 May 2025
- Published by Elsevier in Developmental Cell
- Vol. 60 (18) , 2434-2444.e5
Myocardium and endocardium of the early mammalian heart tube arise from independent multipotent lineages specified at the primitive streak
- 27 May 2025
- Published by Elsevier in Developmental Cell
- Vol. 60 (18) , 2434-2444.e5
Open AccessMyocardium and endocardium of the early mammalian heart tube arise from independent multipotent lineages specified at the primitive streak
- 12 July 2022
- Published by MyJove Corporation in Journal of Visualized Experiments
- No. 185,p. e64273
Live Imaging of Early Cardiac Progenitors in the Mouse Embryo
The first steps of heart development imply drastic changes in cell behavior and differentiation. While analysis of fixed embryos allows studying in detail specific developmental stages in a still snapshot, live imaging captures dynamic morphogenetic events, such as cell migration, shape changes, and differentiation, by imaging the embryo as it develops. This complements fixed analysis and expands the understanding of how organs develop during embryogenesis. Despite its advantages, live imaging is rarely used in mouse models because of its technical challenges. Early mouse embryos are sensitive when cultured ex vivo and require efficient handling. To facilitate a broader use of live imaging in mouse developmental research, this paper presents a detailed protocol for two-photon live microscopy that allows long-term acquisition in mouse embryos. In addition to the protocol, tips are provided on embryo handling and culture optimization. This will help understand key events in early mouse organogenesis, enhancing the understanding of cardiovascular progenitor biology.
- 12 July 2022
- Published by MyJove Corporation in Journal of Visualized Experiments
- No. 185,p. e64273
Live Imaging of Early Cardiac Progenitors in the Mouse Embryo
The first steps of heart development imply drastic changes in cell behavior and differentiation. While analysis of fixed embryos allows studying in detail specific developmental stages in a still snapshot, live imaging captures dynamic morphogenetic events, such as cell migration, shape changes, and differentiation, by imaging the embryo as it develops. This complements fixed analysis and expands the understanding of how organs develop during embryogenesis. Despite its advantages, live imaging is rarely used in mouse models because of its technical challenges. Early mouse embryos are sensitive when cultured ex vivo and require efficient handling. To facilitate a broader use of live imaging in mouse developmental research, this paper presents a detailed protocol for two-photon live microscopy that allows long-term acquisition in mouse embryos. In addition to the protocol, tips are provided on embryo handling and culture optimization. This will help understand key events in early mouse organogenesis, enhancing the understanding of cardiovascular progenitor biology.