Junchao Qi
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
Junchao Qi has a total of 3 co-authors. Here are the top co-authors by number of shared publications:
- Fengshou Wu
Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Key Laboratory of Novel Biomass-Based Environmental and Energy Materials in Petroleum and Chemical Industry, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan, 430072, PR China
1 shared publication - Long Tian
Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Key Laboratory of Novel Biomass-Based Environmental and Energy Materials in Petroleum and Chemical Industry, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430072, China
1 shared publication - Yudong Pang
Hubei Key Laboratory of Novel Reactor and Green Chemical Technology, Key Laboratory of Novel Biomass-Based Environmental and Energy Materials in Petroleum and Chemical Industry, School of Chemical Engineering and Pharmacy, Wuhan Institute of Technology, Wuhan 430072, China
1 shared publication
Latest Publications
- Open Access
Manganese Phthalocyanine-Based Magnetic Core–Shell Composites with Peroxidase Mimetic Activity for Colorimetric Detection of Ascorbic Acid and Glutathione
Ascorbic acid (AA) and glutathione (GSH) play a pivotal role in health assessment, drug development, and quality control of nutritional supplements. The development of a new and efficient method for their detection is highly desired. In this work, we fabricated magnetic core–shell nanocomposites (Fe3O4@MnPc-NDs) by a one-pot hydrothermal method with citric acid and manganese tetraamino phthalocyanine (MnTAPc) as precursors. Fe3O4@MnPc-NDs exhibited enhanced peroxidase activity compared to bare Fe3O4 nanoparticles, enabling catalytic oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue ox-TMB in the presence of H2O2. Leveraging the antioxidant properties of AA/GSH to reduce ox-TMB, a colorimetric assay achieved a low detection limit of 0.161 μM for AA and 0.188 μM for GSH with broad linear ranges. Moreover, this method displayed high specificity against 12 interfering substances and excellent recyclability (>90% activity after five cycles). Finally, the Fe3O4@MnPc-NDs could act as an efficient colorimetric sensor for accurately detecting AA in genuine VC tablets and GSH in whitening serums with high accuracy. Therefore, Fe3O4@MnPc-NDs exhibited great potential in bioassay applications, benefiting from their outstanding sensitivity and high recycling rate.
Open AccessManganese Phthalocyanine-Based Magnetic Core–Shell Composites with Peroxidase Mimetic Activity for Colorimetric Detection of Ascorbic Acid and Glutathione
Ascorbic acid (AA) and glutathione (GSH) play a pivotal role in health assessment, drug development, and quality control of nutritional supplements. The development of a new and efficient method for their detection is highly desired. In this work, we fabricated magnetic core–shell nanocomposites (Fe3O4@MnPc-NDs) by a one-pot hydrothermal method with citric acid and manganese tetraamino phthalocyanine (MnTAPc) as precursors. Fe3O4@MnPc-NDs exhibited enhanced peroxidase activity compared to bare Fe3O4 nanoparticles, enabling catalytic oxidation of colorless 3,3′,5,5′-tetramethylbenzidine (TMB) to blue ox-TMB in the presence of H2O2. Leveraging the antioxidant properties of AA/GSH to reduce ox-TMB, a colorimetric assay achieved a low detection limit of 0.161 μM for AA and 0.188 μM for GSH with broad linear ranges. Moreover, this method displayed high specificity against 12 interfering substances and excellent recyclability (>90% activity after five cycles). Finally, the Fe3O4@MnPc-NDs could act as an efficient colorimetric sensor for accurately detecting AA in genuine VC tablets and GSH in whitening serums with high accuracy. Therefore, Fe3O4@MnPc-NDs exhibited great potential in bioassay applications, benefiting from their outstanding sensitivity and high recycling rate.