Lijian Li

Recently, prototype learning has emerged in semi-supervised medical image segmentation and achieved remarkable performance. However, the scarcity of labeled data limits the expressiveness of prototypes in previous methods, potentially hindering the complete representation of prototypes for class embedding. To overcome this issue, we propose an efficient prototype consistency learning via joint uncertainty quantification and data augmentation (EPCL-JUDA) to enhance the semantic expression of prototypes based on the framework of Mean-Teacher. The concatenation of original and augmented labeled data is fed into student network to generate expressive prototypes. Then, a joint uncertainty quantification method is devised to optimize pseudo-labels and generate reliable prototypes for original and augmented unlabeled data separately. High-quality global prototypes for each class are formed by fusing labeled and unlabeled prototypes, which are utilized to generate prototype-to-features to conduct consistency learning. Notably, a prototype network is proposed to reduce high memory requirements brought by the introduction of augmented data. Extensive experiments on Left Atrium, Pancreas-NIH, Type B Aortic Dissection datasets demonstrate EPCL-JUDA's superiority over previous state-of-the-art approaches, confirming the effectiveness of our framework. The code will be released soon.

Existing semi-supervised medical segmentation co-learning frameworks have realized that model performance can be diminished by the biases in model recognition caused by low-quality pseudo-labels. Due to the averaging nature of their pseudo-label integration strategy, they fail to explore the reliability of pseudo-labels from different sources. In this paper, we propose a mutual evidential deep learning (MEDL) framework that offers a potentially viable solution for pseudo-label generation in semi-supervised learning from two perspectives. First, we introduce networks with different architectures to generate complementary evidence for unlabeled samples and adopt an improved class-aware evidential fusion to guide the confident synthesis of evidential predictions sourced from diverse architectural networks. Second, utilizing the uncertainty in the fused evidence, we design an asymptotic Fisher information-based evidential learning strategy. This strategy enables the model to initially focus on unlabeled samples with more reliable pseudo-labels, gradually shifting attention to samples with lower-quality pseudo-labels while avoiding over-penalization of mislabeled classes in high data uncertainty samples. Additionally, for labeled data, we continue to adopt an uncertainty-driven asymptotic learning strategy, gradually guiding the model to focus on challenging voxels. Extensive experiments on five mainstream datasets have demonstrated that MEDL achieves state-of-the-art performance.

Open-world long-tailed semi-supervised learning (OLSSL) has increasingly attracted attention. However, existing OLSSL algorithms generally assume that the distributions between known and novel categories are nearly identical. Against this backdrop, we construct a more \emph{Realistic Open-world Long-tailed Semi-supervised Learning} (\textbf{ROLSSL}) setting where there is no premise on the distribution relationships between known and novel categories. Furthermore, even within the known categories, the number of labeled samples is significantly smaller than that of the unlabeled samples, as acquiring valid annotations is often prohibitively costly in the real world. Under the proposed ROLSSL setting, we propose a simple yet potentially effective solution called dual-stage post-hoc logit adjustments. The proposed approach revisits the logit adjustment strategy by considering the relationships among the frequency of samples, the total number of categories, and the overall size of data. Then, it estimates the distribution of unlabeled data for both known and novel categories to dynamically readjust the corresponding predictive probabilities, effectively mitigating category bias during the learning of known and novel classes with more selective utilization of imbalanced unlabeled data. Extensive experiments on datasets such as CIFAR100 and ImageNet100 have demonstrated performance improvements of up to 50.1\%, validating the superiority of our proposed method and establishing a strong baseline for this task. For further researches, the anonymous link to the experimental code is at \href{https://github.com/heyuanpengpku/ROLSSL}{\textcolor{brightpink}{https://github.com/heyuanpengpku/ROLSSL}}

Recently, prototype learning has emerged in semi-supervised medical image segmentation and achieved remarkable performance. However, the scarcity of labeled data limits the expressiveness of prototypes in previous methods, potentially hindering the complete representation of prototypes for class embedding. To address this problem, we propose the Mixed Prototype Consistency Learning (MPCL) framework, which includes a Mean Teacher and an auxiliary network. The Mean Teacher generates prototypes for labeled and unlabeled data, while the auxiliary network produces additional prototypes for mixed data processed by CutMix. Through prototype fusion, mixed prototypes provide extra semantic information to both labeled and unlabeled prototypes. High-quality global prototypes for each class are formed by fusing two enhanced prototypes, optimizing the distribution of hidden embeddings used in consistency learning. Extensive experiments on the left atrium and type B aortic dissection datasets demonstrate MPCL's superiority over previous state-of-the-art approaches, confirming the effectiveness of our framework. The code will be released soon.

Strigolactones (SLs) are a novel class of plant hormones that play critical roles in regulating various developmental processes and stress tolerance. Although the SL biosynthetic and signaling genes were already determined in some plants such as Arabidopsis and rice, the information of SL-related genes in grapevine (Vitis vinifera L.) remains largely unknown. In this study, the SL-related genes were identified from the whole grapevine genome, and their expression patterns under salt and drought stresses were determined. The results indicated that the five genes that involved in the SL biosynthesis included one each of the D27, CCD7, CCD8, MAX1 and LBO genes, as well as the three genes that involved in the SL signaling included one each of the D14, MAX2, D53 genes. Phylogenetic analysis suggested that these SL-related proteins are highly conserved among different plant species. Promoter analysis showed that the prevalence of a variety of cis-acting elements associated with hormones and abiotic stress existed in the promoter regions of these SL-related genes. Furthermore, the transcription expression analysis demonstrated that most SL-related genes are involved in the salt and drought stresses response in grapevine. These findings provided valuable information for further investigation and functional analysis of SL biosynthetic and signaling genes in response to salt and drought stresses in grapevine.