Cruz-Botto Sara
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Cruz-Botto Sara has a total of 8 co-authors. Here are the top co-authors by number of shared publications:
- Natalia Villamizar
Universidad del Magdalena, Santa Marta, Colombia, Colombia
2 shared publications - Alejandro Reyes-Bermudez
Facultad de Ciencias Básicas, Programa de Biología, Universidad de la Amazonía
1 shared publication - Fanny Noisette
Institut des sciences de la mer de Rimouski, Université du Québec à Rimouski, Rimouski G5L 3A1, Québec, 310, Allée des Ursulines, C.P. 3300, Canada
1 shared publication - Guardiola Jose Luis
Universidad del Magdalena, Santa Marta 470004, Colombia
1 shared publication - Héctor Alejandro Rodríguez Cabal
Grupo de Biotecnología Vegetal, Facultad de Ciencias Agrarias, Universidad Nacional de Colombia Sede Medellín, Medellín 050034, Colombia
1 shared publication - Saeko Gaitán-Ibarra
University of Magdalena
1 shared publication
Latest Publications
- Open Access
- 8 July 2025
- Published by MDPI AG in Preprints.org
Synergistic Effect of Salinity and 17β-Estradiol on the Induced Feminization of Centropomus undecimalis: Histological, Hormonal, and Molecular Evaluation
The feminization of the protandric teleost Centropomus undecimalis was evaluated under contrasting salinity conditions using 17β-estradiol (E2) administered orally to juveniles and via implants to adults. Two factorial experiments were designed to assess the hormonal effect on histological, hormonal, molecular, and zootechnical indicators. A 100% feminization rate was achieved in both life stages, confirmed by histological analysis and the expression of female sex- and reproduction-related genes (foxl2a, cyp19a1a, zar1l, ddx5, and H2A), particularly in marine environments. Hormonal assays showed increased plasma vitellogenin and decreased 11-ketotestosterone in treated groups, indicating suppression of male endocrine pathways. Zootechnical performance was not significantly affected in adults, but juveniles reared in freshwater exhibited better feed conversion and protein efficiency, likely due to lower osmoregulatory demands. These findings demonstrate that E2-induced feminization is highly effective in C. undecimalis across different salinities, with improved physiological outcomes in freshwater conditions. This study provides valuable insight into the reproductive manipulation of a commercially important species and supporting its sustainable aquaculture.
- 8 July 2025
- Published by MDPI AG in Preprints.org
Open AccessSynergistic Effect of Salinity and 17β-Estradiol on the Induced Feminization of Centropomus undecimalis: Histological, Hormonal, and Molecular Evaluation
The feminization of the protandric teleost Centropomus undecimalis was evaluated under contrasting salinity conditions using 17β-estradiol (E2) administered orally to juveniles and via implants to adults. Two factorial experiments were designed to assess the hormonal effect on histological, hormonal, molecular, and zootechnical indicators. A 100% feminization rate was achieved in both life stages, confirmed by histological analysis and the expression of female sex- and reproduction-related genes (foxl2a, cyp19a1a, zar1l, ddx5, and H2A), particularly in marine environments. Hormonal assays showed increased plasma vitellogenin and decreased 11-ketotestosterone in treated groups, indicating suppression of male endocrine pathways. Zootechnical performance was not significantly affected in adults, but juveniles reared in freshwater exhibited better feed conversion and protein efficiency, likely due to lower osmoregulatory demands. These findings demonstrate that E2-induced feminization is highly effective in C. undecimalis across different salinities, with improved physiological outcomes in freshwater conditions. This study provides valuable insight into the reproductive manipulation of a commercially important species and supporting its sustainable aquaculture.