William Mannherz
Current Organizations / Institutes
The organizations/institutes from the scholar's latest article
Research Subjects
Research Interests
William Mannherz has a total of 13 co-authors. Here are the top co-authors by number of shared publications:
- Ankur Tiwari
Department of Surgery, University of Texas Health Science Center San Antonio
1 shared publication - Daniel Lee
Stanford University
1 shared publication - David E. Cantonwine
Division of Maternal-Fetal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA
1 shared publication - Henning Tiemeier
Department of Child and Adolescent Psychiatry/Psychology Erasmus University Medical Center Rotterdam The Netherlands
1 shared publication - James Selib Michaelson
Laboratory for Quantitative Medicine, and Departments of Pathology and Surgery, Massachusetts General Hospital, Department of Pathology, Harvard Medical School, Boston MA USA
1 shared publication - Jessica Su
Ultrasound Systems, Philips
1 shared publication
Latest Publications
- Open Access
The Binary Cellular Biology of Human Growth : I. Quantifying the Creation and Growth of the Body and its Parts
Assessing and understanding the Growth and Development of animals generally, and of human fetuses specifically, provides essential information for the management of the health of the newborn and its mother. Here we show that a consideration of the formation of the body, in units of numbers of cells, N , and the change in these numbers by the binary either/or decisions of cells to divide or not, an approach we call Binary Cellular Analysis , provides new insights and new equations for quantifying the growth and development of the body and its parts. These equations include: 1) The Binary Cellular Universal Growth Equation , which captures growth from conception to adulthood, and provides a method for biologically-based, data-driven, Growth Curves ; 2) The Binary Cellular Universal Mitotic Fraction Equation , which lies within the Binary Cellular Universal Growth Equation , and captures the mechanism of growth to adult size, control of cell division; 3) The Binary Cellular Allometric Growth Equation , which captures the creation and growth of the Tissues, Organs , and Anatomical Structures of the body, and how the embryo creates each Body Part from a Single Founder Cell ; and, 4) Binary Cellular Estimated Fetal Weight Equations , derived from the Binary Cellular Allometric Growth Equation , which captures the relationship between Ultrasound Measurement and the Size of the body as a whole. These equations capture the developmental process of Cellular Selection , resulting from Differential Cellular Proliferation , which molds the formation of the body from a single fertilized ovum into a multicellular animal. The parameters of these equations both capture the differences in Size and Growth between animals across the taxonomic spectrum, and between human fetuses, as well as identify the individual mechanisms of mitosis that drive Growth and Development . From the Binary Cellular Universal Growth Equation , the Growth of human fetuses can be measured, thus providing a much-needed tool for understanding the biological forces that cause a fetus to grow to Small, Average , or Large Size at birth, for providing the basis of biologically-based, data-driven, Growth Curves , and for assisting the management of the obstetric care of the fetus and its mother.
Open AccessThe Binary Cellular Biology of Human Growth : I. Quantifying the Creation and Growth of the Body and its Parts
Assessing and understanding the Growth and Development of animals generally, and of human fetuses specifically, provides essential information for the management of the health of the newborn and its mother. Here we show that a consideration of the formation of the body, in units of numbers of cells, N , and the change in these numbers by the binary either/or decisions of cells to divide or not, an approach we call Binary Cellular Analysis , provides new insights and new equations for quantifying the growth and development of the body and its parts. These equations include: 1) The Binary Cellular Universal Growth Equation , which captures growth from conception to adulthood, and provides a method for biologically-based, data-driven, Growth Curves ; 2) The Binary Cellular Universal Mitotic Fraction Equation , which lies within the Binary Cellular Universal Growth Equation , and captures the mechanism of growth to adult size, control of cell division; 3) The Binary Cellular Allometric Growth Equation , which captures the creation and growth of the Tissues, Organs , and Anatomical Structures of the body, and how the embryo creates each Body Part from a Single Founder Cell ; and, 4) Binary Cellular Estimated Fetal Weight Equations , derived from the Binary Cellular Allometric Growth Equation , which captures the relationship between Ultrasound Measurement and the Size of the body as a whole. These equations capture the developmental process of Cellular Selection , resulting from Differential Cellular Proliferation , which molds the formation of the body from a single fertilized ovum into a multicellular animal. The parameters of these equations both capture the differences in Size and Growth between animals across the taxonomic spectrum, and between human fetuses, as well as identify the individual mechanisms of mitosis that drive Growth and Development . From the Binary Cellular Universal Growth Equation , the Growth of human fetuses can be measured, thus providing a much-needed tool for understanding the biological forces that cause a fetus to grow to Small, Average , or Large Size at birth, for providing the basis of biologically-based, data-driven, Growth Curves , and for assisting the management of the obstetric care of the fetus and its mother.