Alica Valachová

*This is an algorithmically generated author record based on publicly available information.

Research Subjects

DNA Damage

Research Interests

Alica Valachová has a total of 31 co-authors. Here are the top co-authors by number of shared publications:

Alexander James Roy Bishop
Greehey Children’s Cancer Research Institute, University of Texas Health at San Antonio, San Antonio, USA
18 shared publications
Amber Yasmeen
Lady Davis Institute for Cancer Research, Jewish General Hospital, McGill University, Montreal, QC H3T1E2, Canada
18 shared publications
Anie Monast
McGill University 3 Rosalind & Morris Goodman Cancer Institute Montréal, Québec, Canada
18 shared publications
Azadeh Arabzadeh
Department of Biochemistry, McGill University, Montreal, Canada
18 shared publications
Brian Raught
Princess Margaret Cancer Centre, University Health Network, Toronto, Canada
18 shared publications
David G. Huntsman
Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada
18 shared publications

Latest Publications

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Open Access
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Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S10 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Characterization of the pathogenic variants of SMARCA4 retaining protein expression
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S10 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Characterization of the pathogenic variants of SMARCA4 retaining protein expression
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Table S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Top 31 compounds identified from the FDA drug screen in BIN-67 cells.
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- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Table S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Top 31 compounds identified from the FDA drug screen in BIN-67 cells.
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S6 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4 loss results in R-Loop accumulation
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- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S6 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4 loss results in R-Loop accumulation
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S11 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
BioID proximity-labeling identifies the association between SMARCA4 and PAF1C
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Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S11 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
BioID proximity-labeling identifies the association between SMARCA4 and PAF1C
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Table S3 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
TSS bound by Pol II and TSS-associated mRNAs significantly regulated by SMARCA4.
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Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Table S3 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
TSS bound by Pol II and TSS-associated mRNAs significantly regulated by SMARCA4.
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S9 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Removal of R-Loops in SCCOHT cells confers resistance to PARP inhibitors
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- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S9 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Removal of R-Loops in SCCOHT cells confers resistance to PARP inhibitors
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S5 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4-deficient ovarian cancer cells depend on BRCA1 for their survival
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- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S5 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4-deficient ovarian cancer cells depend on BRCA1 for their survival
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S4 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SCCOHT cells display homologous recombination repair impairment
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- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S4 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SCCOHT cells display homologous recombination repair impairment
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Differential drug responses of SCCOHT cells and ovarian controls.
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S1 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
Differential drug responses of SCCOHT cells and ovarian controls.
Open Access
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Figure S2 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4 modulates response to PARP inhibitors
Website
Google Scholar
- 15 August 2025
- Published by American Association for Cancer Research (AACR)
Open Access
Figure S2 from SMARCA4 Loss Increases RNA Polymerase II Pausing and Elevates R-Loops to Inhibit BRCA1-Mediated Repair in Ovarian Cancer
by Xianbing Zhu, Zheng Fu, Giulio Aceto, Jonathan St-Germain, Kexin Liu, Azadeh Arabzadeh, Yuxuan Qi, Yibo Xue, Leora Witkowski, Elise Graulich, et al.
SMARCA4 modulates response to PARP inhibitors

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