Ekaterina Kononova
Research Subjects
Research Interests
Ekaterina Kononova has a total of 6 co-authors. Here are the top co-authors by number of shared publications:
- Afshona Anoyatbekova
Laboratory of Biochemistry and Molecular Biology, Federal State Budget Scientific Institution “Federal Scientific Center VIEV” (FSC VIEV), Russia
1 shared publication Alexey Gulyukin
Federal State Budget Scientific Institution “Federal Scientific Center VIEV”, Moscow 109428, Russia
1 shared publication- Alina Komina
Federal State Budget Scientific Institution “Federal Scientific Center VIEV”, Moscow, Russia
1 shared publication - Anton G. Yuzhakov
Federal State Budget Scientific Institution “Federal Scientific Center VIEV” (FSC VIEV), Moscow, Russia
1 shared publication - Natalia N. Vlasova
Federal Scientific Center – All-Russian Research Institute of Experimental Veterinary Medicine named after K.I. Skryabin and Ya.O. Kovalenko, Russian Academy of Sciences
1 shared publication - Nikita Krasnikov
Federal State Budget Scientific Institution “Federal Scientific Center VIEV” (FSC VIEV), Moscow, Russia
1 shared publication
Latest Publications
- Open Access
- 1 June 2025
- Published by MDPI AG in Veterinary Sciences
- Vol. 12 (6) , 535
Molecular Detection of Porcine Parvovirus 5 in Domestic Pigs in Russia and Propagation of Field Isolates in Primary Porcine Testicular Cells
Porcine parvovirus 5 (PPV5) is a novel virus frequently detected in pigs worldwide. However, its identification and prevalence in domestic pigs in Russia have not been described. In this study, retrospectively, 984 serum samples collected between 2020 and 2023 were tested by qPCR. All samples were obtained from 20 pig farms located in 10 regions of Russia. PPV5 circulation was confirmed in 11 pig farms with the overall detection rate at 8.9%. The highest detection rate was estimated in the farms of the Belgorod Region (17.1%), followed by the Sverdlovsk Region (15.9%), the Republic of Buryatia (14.7%), and the Moscow Region (14.0%). It has been confirmed that PPV5 has been circulating in the swine population since at least 2021. The phylogenetic analysis revealed a high nucleotide identity of Russian isolates with strains from the USA, Colombia, and China. The Moscow-4060 strain was isolated in primary porcine testicular cells (PPTCs), and its continuous replication was confirmed by qPCR. During microscopy, cytoplasmic vacuolization, pyknosis, and other alterations were observed. The results demonstrate the evidence of PPV5 circulation in domestic pigs in Russia and the first isolation of the virus ever described. These findings serve as a first step for studying PPV5 in vivo.
- 1 June 2025
- Published by MDPI AG in Veterinary Sciences
- Vol. 12 (6) , 535
Open AccessMolecular Detection of Porcine Parvovirus 5 in Domestic Pigs in Russia and Propagation of Field Isolates in Primary Porcine Testicular Cells
Porcine parvovirus 5 (PPV5) is a novel virus frequently detected in pigs worldwide. However, its identification and prevalence in domestic pigs in Russia have not been described. In this study, retrospectively, 984 serum samples collected between 2020 and 2023 were tested by qPCR. All samples were obtained from 20 pig farms located in 10 regions of Russia. PPV5 circulation was confirmed in 11 pig farms with the overall detection rate at 8.9%. The highest detection rate was estimated in the farms of the Belgorod Region (17.1%), followed by the Sverdlovsk Region (15.9%), the Republic of Buryatia (14.7%), and the Moscow Region (14.0%). It has been confirmed that PPV5 has been circulating in the swine population since at least 2021. The phylogenetic analysis revealed a high nucleotide identity of Russian isolates with strains from the USA, Colombia, and China. The Moscow-4060 strain was isolated in primary porcine testicular cells (PPTCs), and its continuous replication was confirmed by qPCR. During microscopy, cytoplasmic vacuolization, pyknosis, and other alterations were observed. The results demonstrate the evidence of PPV5 circulation in domestic pigs in Russia and the first isolation of the virus ever described. These findings serve as a first step for studying PPV5 in vivo.